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    MYCBPAP MYCBP associated protein [ Homo sapiens ]

    Gene ID: 84073, updated on 11-May-2012
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    Summary

    Official Symbol
    MYCBPAPprovided by HGNC
    Official Full Name
    MYCBP associated proteinprovided by HGNC
    Primary source
    HGNC:19677
    See related
    Ensembl:ENSG00000136449; HPRD:11378; MIM:609835; Vega:OTTHUMG00000157184
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    AMAP1; AMAP-1; DKFZp434N1415
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    Genomic context

    Location :
    17q21.33
    Sequence :
    Chromosome: 17; NC_000017.10 (48585745..48608862)
    See MYCBPAP in Epigenomics, MapViewer

    Chromosome 17 - NC_000017.10Genomic Context describing neighboring genes Neighboring gene acyl-CoA synthetase family member 2 Neighboring gene chondroadherin Neighboring gene radical S-adenosyl methionine domain containing 1 Neighboring gene epsin 3 Neighboring gene spermatogenesis associated 20

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. IRES-mediated translational control of AMAP1 expression during differentiation of monocyte U937 cells. Miyata M, et al. Cell Cycle, 2008 Oct. PMID 18843202.
    2. Large-scale mapping of human protein-protein interactions by mass spectrometry. Ewing RM, et al. Mol Syst Biol, 2007. PMID 17353931.
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
    4. AMAP-1, a novel testis-specific AMY-1-binding protein, is differentially expressed during the course of spermatogenesis. Yukitake H, et al. Biochim Biophys Acta, 2002 Aug 19. PMID 12151104.
    5. Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. Wiemann S, et al. Genome Res, 2001 Mar. PMID 11230166.

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Results indicate that monocyte differentiation involves enhancement of IRES activity, by which protein levels of AMAP1 are primarily upregulated.
      Title: IRES-mediated translational control of AMAP1 expression during differentiation of monocyte U937 cells.
    2. sequence analysis of AMAP-1 and identification of AMY-1 as binding protein
      Title: AMAP-1, a novel testis-specific AMY-1-binding protein, is differentially expressed during the course of spermatogenesis.
    Submit: New GeneRIF Correction
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    Phenotypes

    Review eQTL and phenotype association data in this region using PheGenI

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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    AMAP 1 Q99417 MYCBP    HPRD  PubMed  
    AMAP 1 P13861 PRKAR2A    HPRD  PubMed  
    BioGRID:123868 BioGRID:107287 CASP4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:123868 BioGRID:116725 CDK19    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:123868 BioGRID:117673 MYCBP    BioGRID  PubMed Affinity Capture-Western; Two-hybrid 
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    General gene information

    Markers

    Genotypes

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    multicellular organismal development IEA
    Inferred from Electronic Annotation
    more info
    		  
    sensory perception of sound IEA
    Inferred from Electronic Annotation
    more info
    		  
    spermatogenesis IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    synaptic transmission ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Preferred Names
    MYCBP-associated protein
    Names
    MYCBP-associated protein
    AMAM-1
    AMY-1-binding protein 1
    AMY1-associating protein 1
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    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_032133.4 → NP_115509.4  MYCBP-associated protein

      Status: VALIDATED

      Source sequence(s)
      AB083068, AK303041
      Consensus CDS
      CCDS32680.2
      UniProtKB/TrEMBL
      B4DZQ1
      UniProtKB/Swiss-Prot
      Q8TBZ2
      Related
      ENSP00000323184, OTTHUMP00000211654, ENST00000323776, OTTHUMT00000347814

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000017.10 Reference GRCh37.p5 Primary Assembly

      Range
      48585745..48608862
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000149.1 Alternate HuRef

      Range
      43953661..43976856
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AC021491.16 (78014..100924) None
    genomic CH471109.2 EAW94608.1
      EAW94609.1
    mRNA AB083068.1 BAB88692.1
    mRNA AK127992.1 BAG54614.1
    mRNA AK303041.1 BAG64163.1
    mRNA AK314052.1 None
    mRNA AL136765.1 CAB66699.2
    mRNA AL832225.1 CAH56203.1
    mRNA BC028393.2 AAH28393.1
    mRNA BC036358.1 None
    mRNA BG718526.1 None
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q658Z8 GenPept UniProtKB/TrEMBL:Q658Z8
    Q8TBZ2.2 GenPept UniProtKB/Swiss-Prot:Q8TBZ2
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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