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Trps1 trichorhinophalangeal syndrome I (human) [ Mus musculus (house mouse) ]

Gene ID: 83925, updated on 21-May-2016
Official Symbol
Trps1provided by MGI
Official Full Name
trichorhinophalangeal syndrome I (human)provided by MGI
Primary source
MGI:MGI:1927616
See related
Ensembl:ENSMUSG00000038679 Vega:OTTMUSG00000044609
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AI115454; AI447310; D15Ertd586e
Orthologs
Location:
15 C; 15 19.18 cM
Exon count:
12
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 15 NC_000081.6 (50654757..50890747, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (50486303..50721587, complement)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene ribosomal protein L17 pseudogene Neighboring gene predicted gene, 41318 Neighboring gene microRNA 1907 Neighboring gene predicted gene, 34446 Neighboring gene predicted gene, 19303

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Chemically induced (ENU) (1) 
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC46754, MGC107472

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
RNA polymerase II transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
transcription factor activity, sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding IBA
Inferred from Biological aspect of Ancestor
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
anatomical structure formation involved in morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
cell development IBA
Inferred from Biological aspect of Ancestor
more info
 
cell fate commitment IBA
Inferred from Biological aspect of Ancestor
more info
 
chondrocyte differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
digestive tract development IBA
Inferred from Biological aspect of Ancestor
more info
 
hair follicle development IMP
Inferred from Mutant Phenotype
more info
PubMed 
heart development IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription, DNA-templated IPI
Inferred from Physical Interaction
more info
PubMed 
organ morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of chondrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transmembrane receptor protein serine/threonine kinase signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
nuclear chromatin ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
transcription factor complex IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
zinc finger transcription factor Trps1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310481.1NP_001297410.1  zinc finger transcription factor Trps1 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC155307, AK142355, CN667090, DV651380
    Consensus CDS
    CCDS79370.1
    UniProtKB/TrEMBL
    Q3UQJ9, V9GX74
    Conserved Domains (2) summary
    smart00401
    Location:895938
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd00202
    Location:899955
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
  2. NM_001310485.1NP_001297414.1  zinc finger transcription factor Trps1 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) is alternatively spliced in the 5' region and contains an additional in-frame exon compared to variant 1. The resulting isoform (3) is shorter than isoform 1.
    Source sequence(s)
    AC155307, AK142355, CN667090, DV651380
    Consensus CDS
    CCDS79371.1
    UniProtKB/TrEMBL
    Q3UQJ9, V9GXE9
    Conserved Domains (2) summary
    smart00401
    Location:706749
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd00202
    Location:710766
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
  3. NM_032000.2NP_114389.2  zinc finger transcription factor Trps1 isoform 2

    See identical proteins and their annotated locations for NP_114389.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) is alternatively spliced at the 5' end and uses an in-frame, downstream start codon compared to variant 1. The resulting isoform (2) has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AC142245, AC155307, DV651380
    Consensus CDS
    CCDS27460.1
    UniProtKB/TrEMBL
    G3UW90
    Related
    ENSMUSP00000129779, OTTMUSP00000065620, ENSMUST00000165201, OTTMUST00000117346
    Conserved Domains (2) summary
    smart00401
    Location:891934
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd00202
    Location:895951
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p3 C57BL/6J

    Range
    50654757..50890747 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011245780.1XP_011244082.1  

    See identical proteins and their annotated locations for XP_011244082.1

    Conserved Domains (2) summary
    smart00401
    Location:902945
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd00202
    Location:906962
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
  2. XM_011245776.1XP_011244078.1  

    See identical proteins and their annotated locations for XP_011244078.1

    Conserved Domains (2) summary
    smart00401
    Location:902945
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd00202
    Location:906962
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
  3. XM_011245778.1XP_011244080.1  

    See identical proteins and their annotated locations for XP_011244080.1

    Conserved Domains (2) summary
    smart00401
    Location:902945
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd00202
    Location:906962
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
  4. XM_006521562.2XP_006521625.1  

    Related
    ENSMUSP00000139115, OTTMUSP00000065623, ENSMUST00000183997, OTTMUST00000117349
    Conserved Domains (2) summary
    smart00401
    Location:706749
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd00202
    Location:710766
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
  5. XM_006521563.2XP_006521626.1  

    Related
    ENSMUSP00000138905, OTTMUSP00000065624, ENSMUST00000184885, OTTMUST00000117350
    Conserved Domains (2) summary
    smart00401
    Location:695738
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd00202
    Location:699755
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
  6. XM_006521560.2XP_006521623.1  

    Conserved Domains (2) summary
    smart00401
    Location:906949
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd00202
    Location:910966
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
  7. XM_006521561.2XP_006521624.1  

    Related
    ENSMUSP00000139017, OTTMUSP00000065622, ENSMUST00000183757, OTTMUST00000117348
    Conserved Domains (2) summary
    smart00401
    Location:895938
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd00202
    Location:899955
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
  8. XM_011245779.1XP_011244081.1  

    See identical proteins and their annotated locations for XP_011244081.1

    Conserved Domains (2) summary
    smart00401
    Location:902945
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd00202
    Location:906962
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
  9. XM_011245777.1XP_011244079.1  

    See identical proteins and their annotated locations for XP_011244079.1

    Conserved Domains (2) summary
    smart00401
    Location:902945
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd00202
    Location:906962
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

Alternate Mm_Celera

Genomic

  1. AC_000037.1 Alternate Mm_Celera

    Range
    52221354..52433937 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)