RPS6KL1 ribosomal protein S6 kinase-like 1 [Homo sapiens] - Gene

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Summary

Official Symbol: RPS6KL1provided by HGNC
Official Full Name: ribosomal protein S6 kinase-like 1provided by HGNC
Primary source: HGNC:20222
See related: Ensembl:ENSG00000198208; HPRD:18004; Vega:OTTHUMG00000171484
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: FLJ35734; MGC11287

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Genomic context

Location :: 14q24.3

Sequence :: Chromosome: 14; NC_000014.8 (75370657..75389145, complement)

See RPS6KL1 in Epigenomics, MapViewer

Chromosome 14 - NC_000014.8 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

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Phenotypes

Review eQTL and phenotype association data in this region using PheGenI

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Function	Evidence Code	Pubs
ATP binding	IEA Inferred from Electronic Annotation more info
nucleotide binding	IEA Inferred from Electronic Annotation more info
protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
ribosome	IEA Inferred from Electronic Annotation more info

General protein information

Preferred Names: ribosomal protein S6 kinase-like 1

Names: ribosomal protein S6 kinase-like 1

NP_113652.2

EC 2.7.11.1

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NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_031464.4 → NP_113652.2 ribosomal protein S6 kinase-like 1

Status: VALIDATED

Source sequence(s)

AC006530, AK299846

Consensus CDS

CCDS9834.2

UniProtKB/TrEMBL

B4DSP6

UniProtKB/Swiss-Prot

Q9Y6S9

Related

ENSP00000351086, ENST00000358328

Conserved Domains (4) summary

cd02677
Location:48 – 120
Blast Score: 283

MIT_SNX15; MIT: domain contained within Microtubule Interacting and Trafficking molecules. This MIT domain sub-family is found in sorting nexin 15 and related proteins. The molecular function of the MIT domain is unclear.

cd05576
Location:384 – 539
Blast Score: 790

STKc_RPK118_like; Catalytic domain of the Protein Serine/Threonine Kinases, RPK118 and similar proteins

smart00745
Location:46 – 120
Blast Score: 243

MIT; Microtubule Interacting and Trafficking molecule domain

cl09925
Location:154 – 236
Blast Score: 379

PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: Build 37.3

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh37.p5 Primary Assembly

Genomic

NC_000014.8 Reference GRCh37.p5 Primary Assembly

Range

75370657..75389145, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

AC_000146.1 Alternate HuRef

Range

55538659..55557147, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

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Related Sequences

Nucleotide		Protein
Heading	Accession and Version	Protein
genomic	AC006530.4	AAD30182.1
genomic	CH471061.1	EAW81203.1
		EAW81204.1
		EAW81205.1
		EAW81206.1
mRNA	AK054800.1	BAB70808.1
mRNA	AK093053.1	None
mRNA	AK131532.1	None
mRNA	AK226137.1	None
mRNA	AK299846.1	BAG61708.1
mRNA	AL390152.1	CAH10661.1
mRNA	BC004540.2	AAH04540.1
mRNA	BC036574.2	None
other-genetic	DQ893012.2	ABM83938.1
other-genetic	EU176753.1	ABW03554.1