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KATNAL2 katanin catalytic subunit A1 like 2 [ Homo sapiens (human) ]

Gene ID: 83473, updated on 12-May-2016
Official Symbol
KATNAL2provided by HGNC
Official Full Name
katanin catalytic subunit A1 like 2provided by HGNC
Primary source
HGNC:HGNC:25387
See related
Ensembl:ENSG00000167216 HPRD:13754; MIM:614697; Vega:OTTHUMG00000179408
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Orthologs
Location:
18q21.1
Exon count:
21
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 18 NC_000018.10 (46917602..47102243)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (44497565..44628614)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372097 Neighboring gene protein inhibitor of activated STAT 2 Neighboring gene ubiquitin specific peptidase 4 (proto-oncogene) pseudogene Neighboring gene transcription elongation factor B subunit 3C like 2 Neighboring gene transcription elongation factor B subunit 3C like Neighboring gene RNA polymerase II transcription factor SIII subunit A3-like Neighboring gene transcription elongation factor B subunit 3C Neighboring gene transcription elongation factor B subunit 3B Neighboring gene uncharacterized LOC105372098 Neighboring gene haloacid dehalogenase like hydrolase domain containing 2 Neighboring gene immediate early response 3 interacting protein 1

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC33211, DKFZp667C165

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
microtubule binding IEA
Inferred from Electronic Annotation
more info
 
microtubule-severing ATPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
cytoplasmic microtubule organization IBA
Inferred from Biological aspect of Ancestor
more info
 
microtubule severing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
microtubule IEA
Inferred from Electronic Annotation
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
katanin p60 ATPase-containing subunit A-like 2
Names
KATNAL2
katanin catalytic subunit A like 2
katanin p60 subunit A like 2
p60 katanin-like 2
NP_112593.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031303.2NP_112593.2  katanin p60 ATPase-containing subunit A-like 2

    Status: VALIDATED

    Source sequence(s)
    AC012254, BC034999, CA311572, CN303333
    Consensus CDS
    CCDS32828.1
    UniProtKB/Swiss-Prot
    Q8IYT4
    Related
    ENSP00000245121, OTTHUMP00000261295, ENST00000245121, OTTHUMT00000446138
    Conserved Domains (2) summary
    cd00009
    Location:185350
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    smart00382
    Location:214351
    AAA; ATPases associated with a variety of cellular activities

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p2 Primary Assembly

    Range
    46917602..47102243
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006722554.2XP_006722617.1  

    See identical proteins and their annotated locations for XP_006722617.1

    UniProtKB/Swiss-Prot
    Q8IYT4
    Related
    ENSP00000348478, OTTHUMP00000261414, ENST00000356157, OTTHUMT00000446326
    Conserved Domains (3) summary
    cd00009
    Location:257422
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    smart00667
    Location:2555
    LisH; Lissencephaly type-1-like homology motif
    smart00382
    Location:286423
    AAA; ATPases associated with a variety of cellular activities
  2. XM_005258357.3XP_005258414.1  

    Conserved Domains (3) summary
    cd00009
    Location:283448
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    smart00667
    Location:5181
    LisH; Lissencephaly type-1-like homology motif
    smart00382
    Location:312449
    AAA; ATPases associated with a variety of cellular activities
  3. XM_005258358.3XP_005258415.1  

    Conserved Domains (3) summary
    cd00009
    Location:282447
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    smart00667
    Location:5181
    LisH; Lissencephaly type-1-like homology motif
    smart00382
    Location:311448
    AAA; ATPases associated with a variety of cellular activities
  4. XM_011526220.1XP_011524522.1  

    Conserved Domains (3) summary
    cd00009
    Location:283446
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    smart00667
    Location:5181
    LisH; Lissencephaly type-1-like homology motif
    smart00382
    Location:312448
    AAA; ATPases associated with a variety of cellular activities
  5. XM_011526221.1XP_011524523.1  

    Conserved Domains (3) summary
    cd00009
    Location:283433
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    smart00667
    Location:5181
    LisH; Lissencephaly type-1-like homology motif
    smart00382
    Location:312441
    AAA; ATPases associated with a variety of cellular activities
  6. XM_011526223.1XP_011524525.1  

    Conserved Domains (3) summary
    cd00009
    Location:283427
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    smart00667
    Location:5181
    LisH; Lissencephaly type-1-like homology motif
    COG0464
    Location:264429
    SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
  7. XM_011526219.1XP_011524521.1  

    Conserved Domains (3) summary
    cd00009
    Location:283446
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    smart00667
    Location:5181
    LisH; Lissencephaly type-1-like homology motif
    COG0464
    Location:264429
    SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
  8. XM_011526222.1XP_011524524.1  

    Conserved Domains (2) summary
    cd00009
    Location:184349
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    smart00382
    Location:213350
    AAA; ATPases associated with a variety of cellular activities
  9. XM_005258361.2XP_005258418.1  

    Conserved Domains (2) summary
    cd00009
    Location:146311
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    smart00382
    Location:175312
    AAA; ATPases associated with a variety of cellular activities

Alternate CHM1_1.1

Genomic

  1. NC_018929.2 Alternate CHM1_1.1

    Range
    44453895..44623785
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)