IYO RPAP1-like, carboxy-terminal protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Gene symbol: IYO
Gene description: RPAP1-like, carboxy-terminal protein
Primary source: Araport:AT4G38440
Locus tag: AT4G38440
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F22I13.210; F22I13_210; MINIYO
Summary: Encodes MINIYO (IYO), a positive regulator of transcriptional elongation that is essential for cells to initiate differentiation.
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Genomic context

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See IYO in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 10

Sequence:: Chromosome: 4; NC_003075.7 (17989067..17994727)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The findings reveal IYO and QQT2 as cofactors for the assembly of Pol II, Pol IV, and Pol V and provide mechanistic insights into how RNA polymerases are assembled in plants.
Title: A Role for MINIYO and QUATRE-QUART2 in the Assembly of RNA Polymerases II, IV, and V in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_120006.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: RPAP1-like, carboxy-terminal protein

NP_195557.2

LOCATED IN: chloroplast; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: RNA polymerase II-associated protein 1, C-terminal (InterPro:IPR013929), RNA polymerase II-associated protein 1, N-terminal (InterPro:IPR013930); Has 276 Blast hits to 220 proteins in 102 species: Archae - 0; Bacteria - 2; Metazoa - 151; Fungi - 65; Plants - 41; Viruses - 0; Other Eukaryotes - 17 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

17989067..17994727

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_120006.3 → NP_195557.2 RPAP1-like, carboxy-terminal protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_195557.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8GYU3, Q9SVE1, Q9SZM5

UniProtKB/TrEMBL

A0A178UUS6, A0A654FWY4

Conserved Domains (2) summary

pfam08620
Location:318 → 396

RPAP1_C; RPAP1-like, C-terminal

pfam08621
Location:210 → 254

RPAP1_N; RPAP1-like, N-terminal