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USP9Y ubiquitin specific peptidase 9, Y-linked [ Homo sapiens (human) ]

Gene ID: 8287, updated on 6-Jul-2014
Official Symbol
USP9Yprovided by HGNC
Official Full Name
ubiquitin specific peptidase 9, Y-linkedprovided by HGNC
Primary source
HGNC:12633
See related
Ensembl:ENSG00000114374; HPRD:02449; MIM:400005; Vega:OTTHUMG00000036469
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DFFRY; SPGFY2
Summary
This gene is a member of the peptidase C19 family. It encodes a protein that is similar to ubiquitin-specific proteases, which cleave the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. [provided by RefSeq, Mar 2009]
See USP9Y in Epigenomics, MapViewer
Location:
Yq11.2
Exon count:
46
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) Y NC_000024.10 (12701231..12860843)
105 previous assembly GRCh37.p13 (GCF_000001405.25) Y NC_000024.9 (14813160..14972768)

Chromosome Y - NC_000024.10Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 14 pseudogene 1 Neighboring gene testis-specific transcript, Y-linked 15 (non-protein coding) Neighboring gene chromodomain protein, Y-linked 4 pseudogene Neighboring gene DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked Neighboring gene calcium/calmodulin-dependent serine protein kinase (MAGUK family) pseudogene 1

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Clone Names

  • FLJ33043

Gene Ontology Provided by GOA

Function Evidence Code Pubs
co-SMAD binding ISS
Inferred from Sequence or Structural Similarity
more info
 
cysteine-type peptidase activity TAS
Traceable Author Statement
more info
PubMed 
ubiquitin-specific protease activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
BMP signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
protein deubiquitination ISS
Inferred from Sequence or Structural Similarity
more info
 
spermatogenesis TAS
Traceable Author Statement
more info
PubMed 
transforming growth factor beta receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
probable ubiquitin carboxyl-terminal hydrolase FAF-Y
Names
probable ubiquitin carboxyl-terminal hydrolase FAF-Y
ubiquitin thioesterase FAF-Y
deubiquitinating enzyme FAF-Y
ubiquitin thiolesterase FAF-Y
fat facets protein-related, Y-linked
ubiquitin-specific protease 9, Y chromosome
ubiquitin-specific processing protease FAF-Y
ubiquitin-specific-processing protease FAF-Y
ubiquitin specific peptidase 9, Y-linked (fat facets-like, Drosophila)
NP_004645.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_008311.1 

    Range
    5001..164609
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_004654.3NP_004645.2  probable ubiquitin carboxyl-terminal hydrolase FAF-Y

    See proteins identical to NP_004645.2

    Status: REVIEWED

    Source sequence(s)
    AF000986, BI754571, CK823170, Y13618
    Consensus CDS
    CCDS14781.1
    UniProtKB/Swiss-Prot
    O00507
    Related
    ENSP00000342812, OTTHUMP00000034631, ENST00000338981, OTTHUMT00000088703
    Conserved Domains (2) summary
    cd02659
    Location:15571960
    Blast Score: 1204
    peptidase_C19C; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam00443
    Location:15581955
    Blast Score: 660
    UCH; Ubiquitin carboxyl-terminal hydrolase

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000024.10 

    Range
    12701231..12860843
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

  1. AC_000156.1 

    Range
    9466609..9625605
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)