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    UBL4A ubiquitin-like 4A [ Homo sapiens ]

    Gene ID: 8266, updated on 11-May-2012
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    Summary

    Official Symbol
    UBL4Aprovided by HGNC
    Official Full Name
    ubiquitin-like 4Aprovided by HGNC
    Primary source
    HGNC:12505
    Locus tag
    XX-FW89031B12.1
    See related
    Ensembl:ENSG00000102178; HPRD:02417; MIM:312070; Vega:OTTHUMG00000013370
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    GDX; G6PD; GET5; MDY2; UBL4; TMA24; DX254E; DXS254E
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    Genomic context

    Location :
    Xq28
    Sequence :
    Chromosome: X; NC_000023.10 (153712056..153714932, complement)
    See UBL4A in Epigenomics, MapViewer

    Chromosome X - NC_000023.10Genomic Context describing neighboring genes Neighboring gene plexin A3 Neighboring gene L antigen family, member 3 Neighboring gene solute carrier family 10 (sodium/bile acid cotransporter family), member 3 Neighboring gene family with sequence similarity 3, member A

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. Lee KA, et al. J Biol Chem, 2011 Dec 2. PMID 21987572.
    2. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. Wagner SA, et al. Mol Cell Proteomics, 2011 Oct. PMID 21890473.
    3. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. Danielsen JM, et al. Mol Cell Proteomics, 2011 Mar. PMID 21139048.
    4. Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.
    5. Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.

    See all (18) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Phenotypes

    Review eQTL and phenotype association data in this region using PheGenI

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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:113885 BioGRID:106931 ASNA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113885 BioGRID:113647 BAG6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113885 BioGRID:107459 CDK9    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113885 BioGRID:116806 FAF2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113885 BioGRID:119636 GET4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113885 BioGRID:115385 HUWE1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113885 BioGRID:120798 NPLOC4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113885 BioGRID:128397 PDE12    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113885 BioGRID:124834 RNF185    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113885 BioGRID:112347 SGTA    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113885 BioGRID:113164 UBC    BioGRID  PubMed Affinity Capture-MS; Reconstituted Complex 
    BioGRID:113885 BioGRID:113200 UFD1L    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113885 BioGRID:114465 USP13    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113885 BioGRID:124884 WDR20    BioGRID  PubMed Affinity Capture-MS 
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    General gene information

    Markers

    Genotypes

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    small conjugating protein ligase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    protein modification process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    tail-anchored membrane protein insertion into ER membrane IMP
    Inferred from Mutant Phenotype
    more info
    		  
    transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    BAT3 complex IDA
    Inferred from Direct Assay
    more info
    		  
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    cytosol IDA
    Inferred from Direct Assay
    more info
    		  
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    General protein information

    Preferred Names
    ubiquitin-like protein 4A
    Names
    ubiquitin-like protein 4A
    ubiquitin-like 4
    ubiquitin-like protein GDX
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    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_014235.3 → NP_055050.1  ubiquitin-like protein 4A

      Status: PROVISIONAL

      Source sequence(s)
      BC043346
      Consensus CDS
      CCDS14754.1
      UniProtKB/Swiss-Prot
      P11441
      Related
      ENSP00000358674, OTTHUMP00000015407, ENST00000369660, OTTHUMT00000037238
      Conserved Domains (2) summary
      TIGR02986
      Location:95 – 149
      Blast Score: 81
      restrict_Alw26I; type II restriction endonuclease, Alw26I/Eco31I/Esp3I family
      cd01807
      Location:1 – 65
      Blast Score: 294
      GDX_N; ubiquitin-like domain of GDX

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000023.10 Reference GRCh37.p5 Primary Assembly

      Range
      153712056..153714932, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000155.1 Alternate HuRef

      Range
      142288568..142290380, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BX664739.3 (3868..6744) None
    genomic CH471172.2 EAW72700.1
    genomic J03589.1 AAA36790.1
    genomic L44140.1 AAA92650.1
    mRNA AK000405.1 None
    mRNA AK293227.1 BAG56766.1
    mRNA BC020254.1 None
    mRNA BC043346.2 AAH43346.1
    mRNA BC053589.1 AAH53589.1
    mRNA M35604.1 None
    other-genetic HQ448528.1 ADQ33007.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    P11441.1 GenPept UniProtKB/Swiss-Prot:P11441
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Medical
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