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Mdh2 malate dehydrogenase 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 81829, updated on 26-May-2016
Official Symbol
Mdh2provided by RGD
Official Full Name
malate dehydrogenase 2provided by RGD
Primary source
RGD:619719
See related
Ensembl:ENSRNOG00000001440
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
Mor1
Summary
catalyzes the conversion of pyruvate or oxaloacetate to malate [RGD, Feb 2006]
Orthologs
Location:
12q12
Exon count:
9
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (23941451..23954406, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 12 NC_005111.3 (25938703..25951658, complement)

Chromosome 12 - NC_005111.4Genomic Context describing neighboring genes Neighboring gene heat shock protein family B (small) member 1 Neighboring gene serine/arginine repetitive matrix 3 Neighboring gene serine/threonine/tyrosine interacting-like 1 Neighboring gene transmembrane protein 120A

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
L-malate dehydrogenase activity IDA
Inferred from Direct Assay
more info
PubMed 
L-malate dehydrogenase activity ISO
Inferred from Sequence Orthology
more info
 
malate dehydrogenase (NADP+) activity IDA
Inferred from Direct Assay
more info
PubMed 
malate dehydrogenase activity IDA
Inferred from Direct Assay
more info
PubMed 
poly(A) RNA binding IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein self-association IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
NADH metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
internal protein amino acid acetylation ISO
Inferred from Sequence Orthology
more info
 
internal protein amino acid acetylation ISS
Inferred from Sequence or Structural Similarity
more info
 
malate metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
malate metabolic process ISO
Inferred from Sequence Orthology
more info
 
oxaloacetate metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
tricarboxylic acid cycle IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
extracellular exosome IEA
Inferred from Electronic Annotation
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
 
mitochondrial matrix IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
myelin sheath IEA
Inferred from Electronic Annotation
more info
 
myelin sheath ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
malate dehydrogenase, mitochondrial
Names
malate dehydrogenase 2, NAD (mitochondrial)
NP_112413.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031151.2NP_112413.2  malate dehydrogenase, mitochondrial precursor

    See identical proteins and their annotated locations for NP_112413.2

    Status: PROVISIONAL

    Source sequence(s)
    BC063165
    UniProtKB/Swiss-Prot
    P04636
    Related
    ENSRNOP00000001958, ENSRNOT00000001958
    Conserved Domains (2) summary
    TIGR01772
    Location:26335
    MDH_euk_gproteo; malate dehydrogenase, NAD-dependent
    cd01337
    Location:26334
    MDH_glyoxysomal_mitochondrial; Glyoxysomal and mitochondrial malate dehydrogenases

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005111.4 Reference Rnor_6.0 Primary Assembly

    Range
    23941451..23954406 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000080.1 Alternate Rn_Celera

    Range
    22657034..22669988 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)