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NUAK2 NUAK family kinase 2 [ Homo sapiens (human) ]

Gene ID: 81788, updated on 8-May-2016
Official Symbol
NUAK2provided by HGNC
Official Full Name
NUAK family kinase 2provided by HGNC
Primary source
HGNC:HGNC:29558
See related
Ensembl:ENSG00000163545 HPRD:12172; MIM:608131; Vega:OTTHUMG00000037196
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SNARK
Orthologs
Location:
1q32.1
Exon count:
8
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 1 NC_000001.11 (205302059..205321791, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (205271191..205290883, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101929459 Neighboring gene transmembrane and coiled-coil domain family 2 Neighboring gene uncharacterized LOC105371696 Neighboring gene kelch domain containing 8A Neighboring gene small nuclear ribonucleoprotein polypeptide G pseudogene 10 Neighboring gene uncharacterized LOC105371698 Neighboring gene LEMD1 antisense RNA 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ90349, DKFZp434J037, DKFZp686F01113

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IDA
Inferred from Direct Assay
more info
PubMed 
magnesium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
actin cytoskeleton organization IDA
Inferred from Direct Assay
more info
PubMed 
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
cellular response to glucose starvation IDA
Inferred from Direct Assay
more info
PubMed 
intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
protein phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
NUAK family SNF1-like kinase 2
Names
NUAK family, SNF1-like kinase, 2
NUAK2
SNF1/AMP activated protein kinase
SNF1/AMP kinase-related kinase
omphalocele kinase 2
NP_112214.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030952.2NP_112214.2  NUAK family SNF1-like kinase 2

    See identical proteins and their annotated locations for NP_112214.2

    Status: VALIDATED

    Source sequence(s)
    AK303577, BC017306
    Consensus CDS
    CCDS1453.1
    UniProtKB/Swiss-Prot
    Q9H093
    UniProtKB/TrEMBL
    B4E0Y5
    Related
    ENSP00000356125, OTTHUMP00000035319, ENST00000367157, OTTHUMT00000090390
    Conserved Domains (2) summary
    smart00220
    Location:97347
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14161
    Location:93347
    STKc_NUAK2; Catalytic domain of the Serine/Threonine Kinase, novel (nua) kinase family NUAK 2

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p2 Primary Assembly

    Range
    205302059..205321791 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011510029.1XP_011508331.1  

    Conserved Domains (2) summary
    smart00220
    Location:38171
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:29171
    PKc_like; Protein Kinases, catalytic domain
  2. XM_005245515.3XP_005245572.1  

    Conserved Domains (1) summary
    cl21453
    Location:156
    PKc_like; Protein Kinases, catalytic domain

Alternate CHM1_1.1

Genomic

  1. NC_018912.2 Alternate CHM1_1.1

    Range
    206694514..206714241 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)