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Amd1 adenosylmethionine decarboxylase 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 81640, updated on 8-May-2016
Official Symbol
Amd1provided by RGD
Official Full Name
adenosylmethionine decarboxylase 1provided by RGD
Primary source
RGD:2104
See related
Ensembl:ENSRNOG00000000585
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
Amd1a; Amd1b
Summary
ubiquitous enzyme found in nearly all mammalian cells; may be involved with cell growth [RGD, Feb 2006]
Orthologs
Location:
20q12
Exon count:
8
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (45384000..45399694, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 20 NC_005119.3 (47103749..47119386, complement)

Chromosome 20 - NC_005119.4Genomic Context describing neighboring genes Neighboring gene ribosome production factor 2 homolog Neighboring gene general transcription factor IIIC, polypeptide 6, alpha Neighboring gene 60S ribosomal protein L36a-like Neighboring gene hypothetical LOC100361424

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
adenosylmethionine decarboxylase activity IDA
Inferred from Direct Assay
more info
PubMed 
adenosylmethionine decarboxylase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
adenosylmethionine decarboxylase activity ISO
Inferred from Sequence Orthology
more info
 
putrescine binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
S-adenosylmethioninamine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
S-adenosylmethionine metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
S-adenosylmethionine metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
in utero embryonic development ISO
Inferred from Sequence Orthology
more info
 
polyamine metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
spermidine biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
spermidine biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
spermidine biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
spermine biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
spermine biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
spermine biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
S-adenosylmethionine decarboxylase proenzyme
Names
S-Adenosylmethionine decarboxylase 1B
S-adenosylmethionine decarboxylase 1
S-adenosylmethionine decarboxylase 1A
SAMDC
adoMetDC
NP_112273.3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031011.3NP_112273.3  S-adenosylmethionine decarboxylase proenzyme

    See identical proteins and their annotated locations for NP_112273.3

    Status: VALIDATED

    Source sequence(s)
    AABR07045373, FM031711, FM123317
    UniProtKB/Swiss-Prot
    P17708
    Related
    ENSRNOP00000000715, ENSRNOT00000000715
    Conserved Domains (1) summary
    pfam01536
    Location:2329
    SAM_decarbox; Adenosylmethionine decarboxylase

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005119.4 Reference Rnor_6.0 Primary Assembly

    Range
    45384000..45399694 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000088.1 Alternate Rn_Celera

    Range
    44399688..44415381 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)