Display Settings:

Format

Send to:

Choose Destination

SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 [ Homo sapiens (human) ]

Gene ID: 81031, updated on 5-Jul-2015
Official Symbol
SLC2A10provided by HGNC
Official Full Name
solute carrier family 2 (facilitated glucose transporter), member 10provided by HGNC
Primary source
HGNC:HGNC:13444
See related
Ensembl:ENSG00000197496; HPRD:05851; MIM:606145; Vega:OTTHUMG00000032657
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ATS; GLUT10
Summary
This gene encodes a member of the class III facilitative glucose transporter family. The encoded protein plays a role in regulation of glucose homeostasis. Mutations in this gene have been associated with arterial tortuosity syndrome.[provided by RefSeq, Dec 2009]
Orthologs
See SLC2A10 in Epigenomics, MapViewer
Location:
20q13.1
Exon count:
8
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 20 NC_000020.11 (46708347..46736347)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (45338279..45364986)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene osteoclast stimulatory transmembrane protein Neighboring gene solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 Neighboring gene TP53 regulating kinase Neighboring gene ribosomal protein L13 pseudogene 14 Neighboring gene uncharacterized LOC101927355 Neighboring gene EYA transcriptional coactivator and phosphatase 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Clone Names

  • MGC126706

Gene Ontology Provided by GOA

Function Evidence Code Pubs
glucose transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
sugar:proton symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
sugar:proton symporter activity NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
glucose import IBA
Inferred from Biological aspect of Ancestor
more info
 
glucose transport NAS
Non-traceable Author Statement
more info
PubMed 
hexose transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
proton transport IBA
Inferred from Biological aspect of Ancestor
more info
 
proton transport NAS
Non-traceable Author Statement
more info
PubMed 
transmembrane transport TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
 
endomembrane system IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane NAS
Non-traceable Author Statement
more info
PubMed 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 
plasma membrane TAS
Traceable Author Statement
more info
 
Preferred Names
solute carrier family 2, facilitated glucose transporter member 10
Names
GLUT-10
glucose transporter type 10

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_016284.1 RefSeqGene

    Range
    5001..31708
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_030777.3NP_110404.1  solute carrier family 2, facilitated glucose transporter member 10

    See identical proteins and their annotated locations for NP_110404.1

    Status: REVIEWED

    Source sequence(s)
    AF248053, AF321240
    Consensus CDS
    CCDS13402.1
    UniProtKB/Swiss-Prot
    O95528
    Related
    ENSP00000352216, OTTHUMP00000031212, ENST00000359271, OTTHUMT00000079578
    Conserved Domains (2) summary
    cd06174
    Location:14497
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00879
    Location:4508
    SP; MFS transporter, sugar porter (SP) family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p2 Primary Assembly

    Range
    46708347..46736347
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011529064.1XP_011527366.1  

    Conserved Domains (2) summary
    cd06174
    Location:35351
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    COG0477
    Location:37344
    ProP; MFS family permease [Carbohydrate transport and metabolism, Amino acid transport and metabolism, Inorganic ion transport and metabolism, General function prediction only]
  2. XM_011529062.1XP_011527364.1  

    Conserved Domains (2) summary
    cd06174
    Location:35351
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    COG0477
    Location:37344
    ProP; MFS family permease [Carbohydrate transport and metabolism, Amino acid transport and metabolism, Inorganic ion transport and metabolism, General function prediction only]
  3. XM_011529063.1XP_011527365.1  

    Conserved Domains (2) summary
    cd06174
    Location:35351
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam00083
    Location:38498
    Sugar_tr; Sugar (and other) transporter
  4. XM_011529065.1XP_011527367.1  

    Conserved Domains (1) summary
    cd06174
    Location:35351
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
  5. XM_011529060.1XP_011527362.1  

    See identical proteins and their annotated locations for XP_011527362.1

    Conserved Domains (2) summary
    cd06174
    Location:35518
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00879
    Location:25529
    SP; MFS transporter, sugar porter (SP) family
  6. XM_011529061.1XP_011527363.1  

    Conserved Domains (2) summary
    cd06174
    Location:17500
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00879
    Location:1511
    SP; MFS transporter, sugar porter (SP) family

RNA

  1. XR_936641.1 RNA Sequence

Alternate CHM1_1.1

Genomic

  1. NC_018931.2 Alternate CHM1_1.1

    Range
    45241287..45267979
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)