Display Settings:

Format

Send to:

Choose Destination

Erap1 endoplasmic reticulum aminopeptidase 1 [ Mus musculus (house mouse) ]

Gene ID: 80898, updated on 24-Jan-2015
Official Symbol
Erap1provided by MGI
Official Full Name
endoplasmic reticulum aminopeptidase 1provided by MGI
Primary source
MGI:MGI:1933403
See related
Ensembl:ENSMUSG00000021583
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Arts1; ERAAP; PILSA; PILSAP
Orthologs
See Erap1 in MapViewer
Location:
13 C1; 13
Exon count:
20
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 13 NC_000079.6 (74639628..74691882)

Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene upstream binding transcription factor, RNA polymerase I pseudogene Neighboring gene stomatin (Epb7.2)-like 2 pseudogene Neighboring gene predicted gene, 30656 Neighboring gene calpastatin Neighboring gene heterogeneous nuclear ribonucleoprotein A1 pseudogene Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like 2, pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
aminopeptidase activity IDA
Inferred from Direct Assay
more info
PubMed 
aminopeptidase activity ISO
Inferred from Sequence Orthology
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
interleukin-6 receptor binding ISO
Inferred from Sequence Orthology
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
metalloexopeptidase activity ISO
Inferred from Sequence Orthology
more info
 
metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
peptidase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
tumor necrosis factor receptor binding ISO
Inferred from Sequence Orthology
more info
 
zinc ion binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
immune system process IEA
Inferred from Electronic Annotation
more info
 
membrane protein ectodomain proteolysis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
proteolysis IDA
Inferred from Direct Assay
more info
PubMed 
proteolysis IMP
Inferred from Mutant Phenotype
more info
PubMed 
proteolysis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum lumen ISO
Inferred from Sequence Orthology
more info
 
extracellular region ISO
Inferred from Sequence Orthology
more info
 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
endoplasmic reticulum aminopeptidase 1
Names
endoplasmic reticulum aminopeptidase 1
A-LAP
ARTS-1
PILS-AP
aminopeptidase PILS
VEGF-induced aminopeptidase
adipocyte-derived leucine aminopeptidase
puromycin-insensitive leucyl-specific aminopeptidase
type 1 tumor necrosis factor receptor shedding aminopeptidase regulator

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030711.4NP_109636.1  endoplasmic reticulum aminopeptidase 1 precursor

    See proteins identical to NP_109636.1

    Status: PROVISIONAL

    Source sequence(s)
    AC138120
    Consensus CDS
    CCDS26647.1
    UniProtKB/Swiss-Prot
    Q9EQH2
    Related
    ENSMUSP00000133166, ENSMUST00000169114
    Conserved Domains (3) summary
    cd09601
    Location:50520
    M1_APN_2; Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ)
    COG0308
    Location:42917
    PepN; Aminopeptidase N [Amino acid transport and metabolism]
    pfam11838
    Location:586905
    ERAP1_C; ERAP1-like C-terminal domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000079.6 

    Range
    74639628..74691882
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006517476.1XP_006517539.1  

    See proteins identical to XP_006517539.1

    UniProtKB/Swiss-Prot
    Q9EQH2
    Conserved Domains (3) summary
    cd09601
    Location:50520
    M1_APN_2; Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ)
    COG0308
    Location:42917
    PepN; Aminopeptidase N [Amino acid transport and metabolism]
    pfam11838
    Location:586905
    ERAP1_C; ERAP1-like C-terminal domain

Alternate Mm_Celera

Genomic

  1. AC_000035.1 

    Range
    76970386..77021970
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)