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    MLF2 myeloid leukemia factor 2 [ Homo sapiens ]

    Gene ID: 8079, updated on 11-May-2012

    Summary

    Official Symbol
    MLF2provided by HGNC
    Official Full Name
    myeloid leukemia factor 2provided by HGNC
    Primary source
    HGNC:7126
    See related
    Ensembl:ENSG00000089693; HPRD:03238; MIM:601401; Vega:OTTHUMG00000168717
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    NTN4

    Genomic context

    Location :
    12p13
    Sequence :
    Chromosome: 12; NC_000012.11 (6857158..6862636, complement)
    See MLF2 in Epigenomics, MapViewer

    Chromosome 12 - NC_000012.11Genomic Context describing neighboring genes Neighboring gene chromosome 12 open reading frame 53 Neighboring gene COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis) Neighboring gene parathymosin Neighboring gene lymphocyte-activation gene 3

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:113752 BioGRID:111783 ABCD3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113752 BioGRID:114579 AIFM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113752 BioGRID:114908 BAG2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113752 BioGRID:114791 CIAO1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113752 BioGRID:971788 EBNA-LP    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113752 BioGRID:119656 FAM96B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113752 BioGRID:122103 MMS19    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113752 BioGRID:115897 PMVK    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113752 BioGRID:111550 PRKAA2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113752 BioGRID:114161 RGS20    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:113752 BioGRID:113164 UBC    BioGRID  PubMed Affinity Capture-MS 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    defense response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    myeloid leukemia factor 2
    Names
    myeloid leukemia factor 2
    myelodysplasia-myeloid leukemia factor 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_005439.2NP_005430.1  myeloid leukemia factor 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) is the protein-coding variant.
      Source sequence(s)
      AK289869, BC002340
      Consensus CDS
      CCDS8559.1
      UniProtKB/TrEMBL
      A8K1F4
      UniProtKB/Swiss-Prot
      Q15773
      UniProtKB/TrEMBL
      Q5U0N1
      Related
      ENSP00000403941, ENST00000435120
      Conserved Domains (1) summary
      pfam10248
      Location:26200
      Blast Score: 546
      Mlf1IP; Myelodysplasia-myeloid leukemia factor 1-interacting protein

    RNA

    1. NR_026581.1 RNA Sequence

      Description
      Transcript Variant: This variant (2) has a short ORF upstream of the longer one annotated on NM_005439.2. The short ORF has a strong Kozak sequence and would likely prevent translation from any downstream AUG. Therefore, this transcript variant is thought to be noncoding.
      Source sequence(s)
      BC002340, BI544309

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000012.11 Reference GRCh37.p5 Primary Assembly

      Range
      6857158..6862636, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000144.1 Alternate HuRef

      Range
      6710655..6716132, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AC125494.2 (45312..50419) None
    genomic CH471116.2 EAW88743.1
      EAW88744.1
    mRNA AF070539.1 AAC28632.1
    mRNA AK289869.1 BAF82558.1
    mRNA AK313998.1 BAG36710.1
    mRNA BC000898.2 AAH00898.1
    mRNA BC002340.2 AAH02340.1
    mRNA BI544309.1 None
    mRNA BT019393.1 AAV38200.1
    mRNA BT019432.1 AAV38239.1
    mRNA CR541700.1 CAG46501.1
    mRNA U57342.1 AAB08988.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q15773.1 GenPept UniProtKB/Swiss-Prot:Q15773
    Q5U0N1 GenPept UniProtKB/TrEMBL:Q5U0N1

      Supplemental Content

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