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ZNF703 zinc finger protein 703 [ Homo sapiens (human) ]

Gene ID: 80139, updated on 26-May-2016
Official Symbol
ZNF703provided by HGNC
Official Full Name
zinc finger protein 703provided by HGNC
Primary source
HGNC:HGNC:25883
See related
Ensembl:ENSG00000183779 HPRD:07855; Vega:OTTHUMG00000164001
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NLZ1; ZPO1; ZEPPO1; ZNF503L
Orthologs
Location:
8p11.23
Exon count:
2
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 8 NC_000008.11 (37695751..37700021)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (37553301..37556396)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105379378 Neighboring gene uncharacterized LOC105379380 Neighboring gene uncharacterized LOC101929622 Neighboring gene uncharacterized LOC102723701 Neighboring gene ER lipid raft associated 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Gene Expression, organism-specific biosystem (from REACTOME)
    Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
  • Generic Transcription Pathway, organism-specific biosystem (from REACTOME)
    Generic Transcription Pathway, organism-specific biosystemOVERVIEW OF TRANSCRIPTION REGULATION: Detailed studies of gene transcription regulation in a wide variety of eukaryotic systems has revealed the general principles and mechanisms by which cell- or t...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ14299

Gene Ontology Provided by GOA

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
repressing transcription factor binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
adherens junction assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to estradiol stimulus IDA
Inferred from Direct Assay
more info
PubMed 
mammary gland epithelial cell differentiation IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of homotypic cell-cell adhesion ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cell migration ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of epithelial to mesenchymal transition ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of mammary gland epithelial cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
regulation of canonical Wnt signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of cell cycle IDA
Inferred from Direct Assay
more info
PubMed 
regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
regulation of transforming growth factor beta receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
nuclear matrix IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
protein complex IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
zinc finger protein 703
Names
zinc finger elbow-related proline domain protein 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025069.2NP_079345.1  zinc finger protein 703

    See identical proteins and their annotated locations for NP_079345.1

    Status: VALIDATED

    Source sequence(s)
    AA527152, BC032534, BM770319, BY996877, DA936465
    Consensus CDS
    CCDS6094.1
    UniProtKB/Swiss-Prot
    Q9H7S9
    Related
    ENSP00000332325, OTTHUMP00000225524, ENST00000331569, OTTHUMT00000376683
    Conserved Domains (2) summary
    pfam12402
    Location:311339
    nlz1; NocA-like zinc-finger protein 1
    sd00017
    Location:458483
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p2 Primary Assembly

    Range
    37695751..37700021
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018919.2 Alternate CHM1_1.1

    Range
    37754705..37758975
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)