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EHMT1 euchromatic histone lysine methyltransferase 1 [ Homo sapiens (human) ]

Gene ID: 79813, updated on 8-May-2016
Official Symbol
EHMT1provided by HGNC
Official Full Name
euchromatic histone lysine methyltransferase 1provided by HGNC
Primary source
HGNC:HGNC:24650
See related
Ensembl:ENSG00000181090 HPRD:07383; MIM:607001; Vega:OTTHUMG00000020995
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GLP; GLP1; KMT1D; FP13812; EUHMTASE1; Eu-HMTase1; bA188C12.1
Summary
The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Orthologs
Location:
9q34.3
Exon count:
37
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 9 NC_000009.12 (137618992..137836127)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (140513444..140730579)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene zinc finger MYND-type containing 19 Neighboring gene ARRDC1 antisense RNA 1 Neighboring gene arrestin domain containing 1 Neighboring gene SET pseudogene 5 Neighboring gene EHMT1 intronic transcript 1 Neighboring gene forkhead box H1 pseudogene Neighboring gene uncharacterized LOC105376330 Neighboring gene uncharacterized LOC100133077 Neighboring gene microRNA 602 Neighboring gene calcium voltage-gated channel subunit alpha1 B

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Associated conditions

Description Tests
Chromosome 9q deletion syndrome
MedGen: C0795833 OMIM: 610253 GeneReviews: Kleefstra Syndrome
Compare labs

Copy number response

Description
Copy number response
Triplosensitivity

Little evidence for dosage pathogenicity (Last evaluated (2012-07-06)

ClinGen Genome Curation PagePubMed
Haploinsufficency

Sufficient evidence for dosage pathogenicity (Last evaluated (2012-07-06)

ClinGen Genome Curation PagePubMed
  • Cellular Senescence, organism-specific biosystem (from REACTOME)
    Cellular Senescence, organism-specific biosystemCellular senescence involves irreversible growth arrest accompanied by phenotypic changes such as enlarged morphology, reorganization of chromatin through formation of senescence-associated heterochr...
  • Cellular responses to stress, organism-specific biosystem (from REACTOME)
    Cellular responses to stress, organism-specific biosystemCells are subject to external molecular and physical stresses such as foreign molecules that perturb metabolic or signaling processes, and changes in temperature or pH. The ability of cells and tissu...
  • Chromatin modifying enzymes, organism-specific biosystem (from REACTOME)
    Chromatin modifying enzymes, organism-specific biosystemEukaryotic DNA is associated with histone proteins and organized into a complex nucleoprotein structure called chromatin. This structure decreases the accessibility of DNA but also helps to protect i...
  • Chromatin organization, organism-specific biosystem (from REACTOME)
    Chromatin organization, organism-specific biosystemChromatin organization refers to the composition and conformation of complexes between DNA, protein and RNA. It is determined by processes that result in the specification, formation or maintenance o...
  • Gene Expression, organism-specific biosystem (from REACTOME)
    Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
  • Generic Transcription Pathway, organism-specific biosystem (from REACTOME)
    Generic Transcription Pathway, organism-specific biosystemOVERVIEW OF TRANSCRIPTION REGULATION: Detailed studies of gene transcription regulation in a wide variety of eukaryotic systems has revealed the general principles and mechanisms by which cell- or t...
  • Longevity regulating pathway, organism-specific biosystem (from KEGG)
    Longevity regulating pathway, organism-specific biosystemRegulation of longevity depends on genetic and environmental factors. Caloric restriction (CR), that is limiting food intake, is recognized in mammals as the best characterized and most reproducible ...
  • Lysine degradation, organism-specific biosystem (from KEGG)
    Lysine degradation, organism-specific biosystem
    Lysine degradation
  • Lysine degradation, conserved biosystem (from KEGG)
    Lysine degradation, conserved biosystem
    Lysine degradation
  • PKMTs methylate histone lysines, organism-specific biosystem (from REACTOME)
    PKMTs methylate histone lysines, organism-specific biosystemLysine methyltransferases (KMTs) and arginine methyltransferases (RMTs) have a common mechanism of catalysis. Both families transfer a methyl group from a common donor, S-adenosyl-L-methionine (SAM),...
  • Regulation of TP53 Activity, organism-specific biosystem (from REACTOME)
    Regulation of TP53 Activity, organism-specific biosystemProtein stability and transcriptional activity of TP53 (p53) tumor suppressor are regulated by post-translational modifications that include ubiquitination, phosphorylation, acetylation, methylation,...
  • Regulation of TP53 Activity through Methylation, organism-specific biosystem (from REACTOME)
    Regulation of TP53 Activity through Methylation, organism-specific biosystemTP53 (p53) undergoes methylation on several lysine and arginine residues, which modulates its transcriptional activity.PRMT5, recruited to TP53 as part of the ATM-activated complex that includes TTC5...
  • Senescence-Associated Secretory Phenotype (SASP), organism-specific biosystem (from REACTOME)
    Senescence-Associated Secretory Phenotype (SASP), organism-specific biosystemThe culture medium of senescent cells in enriched in secreted proteins when compared with the culture medium of quiescent i.e. presenescent cells and these secreted proteins constitute the so-called ...
  • Transcriptional Regulation by TP53, organism-specific biosystem (from REACTOME)
    Transcriptional Regulation by TP53, organism-specific biosystemThe tumor suppressor TP53 (encoded by the gene p53) is a transcription factor. Under stress conditions, it recognizes specific responsive DNA elements and thus regulates the transcription of many gen...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ12879, KIAA1876, DKFZp667M072

Gene Ontology Provided by GOA

Function Evidence Code Pubs
C2H2 zinc finger domain binding IEA
Inferred from Electronic Annotation
more info
 
histone methyltransferase activity (H3-K27 specific) ISS
Inferred from Sequence or Structural Similarity
more info
 
histone methyltransferase activity (H3-K9 specific) ISS
Inferred from Sequence or Structural Similarity
more info
 
histone-lysine N-methyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
methyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
p53 binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein-lysine N-methyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
DNA methylation ISS
Inferred from Sequence or Structural Similarity
more info
 
chromatin modification IDA
Inferred from Direct Assay
more info
PubMed 
embryo development ISS
Inferred from Sequence or Structural Similarity
more info
 
histone H3-K27 methylation IEA
Inferred from Electronic Annotation
more info
 
histone H3-K9 methylation IEA
Inferred from Electronic Annotation
more info
 
histone methylation IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription, DNA-templated ISS
Inferred from Sequence or Structural Similarity
more info
 
peptidyl-lysine dimethylation IDA
Inferred from Direct Assay
more info
PubMed 
peptidyl-lysine monomethylation ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of signal transduction by p53 class mediator TAS
Traceable Author Statement
more info
 
response to fungicide IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
chromosome IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleoplasm TAS
Traceable Author Statement
more info
 
nucleus IC
Inferred by Curator
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
histone-lysine N-methyltransferase EHMT1
Names
G9a-like protein 1
H3-K9-HMTase 5
euchromatic histone-lysine N-methyltransferase 1
histone H3-K9 methyltransferase 5
histone-lysine N-methyltransferase, H3 lysine-9 specific 5
lysine N-methyltransferase 1D
NP_001138999.1
NP_079033.4

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_011776.1 RefSeqGene

    Range
    5001..222136
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001145527.1NP_001138999.1  histone-lysine N-methyltransferase EHMT1 isoform 2

    See identical proteins and their annotated locations for NP_001138999.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter and has a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AB028932, BC047504, BM681619
    Consensus CDS
    CCDS56595.1
    UniProtKB/Swiss-Prot
    Q9H9B1
    Related
    ENSP00000417328, OTTHUMP00000212228, ENST00000462484, OTTHUMT00000348982
    Conserved Domains (2) summary
    cd00204
    Location:742796
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam13637
    Location:742793
    Ank_4; Ankyrin repeats (many copies)
  2. NM_024757.4NP_079033.4  histone-lysine N-methyltransferase EHMT1 isoform 1

    See identical proteins and their annotated locations for NP_079033.4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AB028932, BC011608, BC047504, CA426038
    Consensus CDS
    CCDS7050.2
    UniProtKB/Swiss-Prot
    Q9H9B1
    Related
    ENSP00000417980, OTTHUMP00000022711, ENST00000460843, OTTHUMT00000055371
    Conserved Domains (7) summary
    smart00317
    Location:11261248
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cd00204
    Location:800926
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:772800
    Ank; Ankyrin repeat
    pfam05033
    Location:10131118
    Pre-SET; Pre-SET motif
    pfam12796
    Location:777870
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:742793
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:924979
    Ank_5; Ankyrin repeats (many copies)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p2 Primary Assembly

    Range
    137618992..137836127
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005266110.1XP_005266167.1  

    See identical proteins and their annotated locations for XP_005266167.1

    Conserved Domains (7) summary
    smart00317
    Location:10951217
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cd00204
    Location:769895
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:741769
    Ank; Ankyrin repeat
    pfam05033
    Location:9821087
    Pre-SET; Pre-SET motif
    pfam12796
    Location:746839
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:711762
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:893948
    Ank_5; Ankyrin repeats (many copies)
  2. XM_011519022.1XP_011517324.1  

    Conserved Domains (7) summary
    smart00317
    Location:11281250
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cd00204
    Location:802928
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:774802
    Ank; Ankyrin repeat
    pfam05033
    Location:10151120
    Pre-SET; Pre-SET motif
    pfam12796
    Location:779872
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:744795
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:926981
    Ank_5; Ankyrin repeats (many copies)
  3. XM_005266105.3XP_005266162.1  

    Conserved Domains (7) summary
    smart00317
    Location:11231245
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cd00204
    Location:797923
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:769797
    Ank; Ankyrin repeat
    pfam05033
    Location:10101115
    Pre-SET; Pre-SET motif
    pfam12796
    Location:774867
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:739790
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:921976
    Ank_5; Ankyrin repeats (many copies)
  4. XM_011519021.1XP_011517323.1  

    Conserved Domains (7) summary
    smart00317
    Location:11291251
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cd00204
    Location:803929
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:775803
    Ank; Ankyrin repeat
    pfam05033
    Location:10161121
    Pre-SET; Pre-SET motif
    pfam12796
    Location:780873
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:745796
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:927982
    Ank_5; Ankyrin repeats (many copies)
  5. XM_011519026.1XP_011517328.1  

    Conserved Domains (7) summary
    smart00317
    Location:10811203
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cd00204
    Location:755881
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:727755
    Ank; Ankyrin repeat
    pfam05033
    Location:9681073
    Pre-SET; Pre-SET motif
    pfam12796
    Location:732825
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:697748
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:879934
    Ank_5; Ankyrin repeats (many copies)
  6. XM_011519024.1XP_011517326.1  

    Conserved Domains (7) summary
    smart00317
    Location:11031225
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cd00204
    Location:777903
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:749777
    Ank; Ankyrin repeat
    pfam05033
    Location:9901095
    Pre-SET; Pre-SET motif
    pfam12796
    Location:754847
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:719770
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:901956
    Ank_5; Ankyrin repeats (many copies)
  7. XM_011519023.1XP_011517325.1  

    Conserved Domains (7) summary
    smart00317
    Location:11221244
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cd00204
    Location:796922
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:768796
    Ank; Ankyrin repeat
    pfam05033
    Location:10091114
    Pre-SET; Pre-SET motif
    pfam12796
    Location:773866
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:738789
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:920975
    Ank_5; Ankyrin repeats (many copies)
  8. XM_011519033.1XP_011517335.1  

    Conserved Domains (7) summary
    smart00317
    Location:10741196
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cd00204
    Location:748874
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:720748
    Ank; Ankyrin repeat
    pfam05033
    Location:9611066
    Pre-SET; Pre-SET motif
    pfam12796
    Location:725818
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:690741
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:872927
    Ank_5; Ankyrin repeats (many copies)
  9. XM_011519027.1XP_011517329.1  

    Conserved Domains (3) summary
    cd00204
    Location:775896
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:813906
    Ank_2; Ankyrin repeats (3 copies)
    cl02529
    Location:745796
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
  10. XM_011519028.1XP_011517330.1  

    Conserved Domains (2) summary
    cd00204
    Location:745799
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam13637
    Location:745796
    Ank_4; Ankyrin repeats (many copies)
  11. XM_011519025.1XP_011517327.1  

    See identical proteins and their annotated locations for XP_011517327.1

    Conserved Domains (7) summary
    smart00317
    Location:10951217
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cd00204
    Location:769895
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:741769
    Ank; Ankyrin repeat
    pfam05033
    Location:9821087
    Pre-SET; Pre-SET motif
    pfam12796
    Location:746839
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:711762
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:893948
    Ank_5; Ankyrin repeats (many copies)
  12. XM_006717288.2XP_006717351.1  

    Conserved Domains (7) summary
    smart00317
    Location:11201242
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cd00204
    Location:794920
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:766794
    Ank; Ankyrin repeat
    pfam05033
    Location:10071112
    Pre-SET; Pre-SET motif
    pfam12796
    Location:771864
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:736787
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:918973
    Ank_5; Ankyrin repeats (many copies)
  13. XM_011519029.1XP_011517331.1  

    Conserved Domains (7) summary
    smart00317
    Location:603725
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cd00204
    Location:277403
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:249277
    Ank; Ankyrin repeat
    pfam05033
    Location:490595
    Pre-SET; Pre-SET motif
    pfam12796
    Location:254347
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:219270
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:401456
    Ank_5; Ankyrin repeats (many copies)
  14. XM_011519030.1XP_011517332.1  

    Conserved Domains (6) summary
    smart00317
    Location:387509
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cd00204
    Location:61187
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:199231
    Ank; Ankyrin repeat
    pfam05033
    Location:274379
    Pre-SET; Pre-SET motif
    pfam12796
    Location:71164
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:5487
    Ank_4; Ankyrin repeats (many copies)
  15. XM_011519031.1XP_011517333.1  

    See identical proteins and their annotated locations for XP_011517333.1

    Conserved Domains (5) summary
    smart00317
    Location:316438
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cd00204
    Location:23149
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:126
    Ank; Ankyrin repeat
    pfam05033
    Location:203308
    Pre-SET; Pre-SET motif
    pfam12796
    Location:193
    Ank_2; Ankyrin repeats (3 copies)
  16. XM_011519032.1XP_011517334.1  

    See identical proteins and their annotated locations for XP_011517334.1

    Conserved Domains (5) summary
    smart00317
    Location:316438
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cd00204
    Location:23149
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:126
    Ank; Ankyrin repeat
    pfam05033
    Location:203308
    Pre-SET; Pre-SET motif
    pfam12796
    Location:193
    Ank_2; Ankyrin repeats (3 copies)

Alternate CHM1_1.1

Genomic

  1. NC_018920.2 Alternate CHM1_1.1

    Range
    140662174..140878710
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)