arr3b arrestin 3b, retinal (X-arrestin) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: arr3bprovided by ZNC
Official Full Name: arrestin 3b, retinal (X-arrestin)provided by ZNC
Primary source: ZFIN:ZDB-GENE-030616-74
See related: Ensembl:ENSDARG00000098475 AllianceGenome:ZFIN:ZDB-GENE-030616-74
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: arr3; zgc:73331; si:bz46j2.6
Summary: Predicted to enable G protein-coupled receptor binding activity. Predicted to be involved in G protein-coupled receptor internalization and visual perception. Predicted to act upstream of or within signal transduction. Is expressed in neural plate; optic primordium; optic vesicle; photoreceptor cell; and visual system. Human ortholog(s) of this gene implicated in myopia. Orthologous to human ARR3 (arrestin 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 14

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (32838163..32849528)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (32497801..32509214)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data show subfunctionalized expression of Arr3a in M- and L-cones, and Arr3b in S- and UV-cones, and suggest that Arr3a deficiency is sufficient to reduce temporal contrast sensitivity.
Title: Cone arrestin confers cone vision of high temporal resolution in zebrafish larvae.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables G protein-coupled receptor binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor internalization	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info
involved_in visual perception	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: arrestin 3b, retinal (X-arrestin)

Names: arrestin 3, retinal (X-arrestin)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200792.1 → NP_957086.1 arrestin 3b, retinal (X-arrestin)

See identical proteins and their annotated locations for NP_957086.1

Status: PROVISIONAL

Source sequence(s)

BC059650

UniProtKB/TrEMBL

A0A8M1PFS4, Q6PBM9

Related

ENSDARP00000141732.1, ENSDART00000158077.3

Conserved Domains (2) summary

smart01017
Location:192 → 353

Arrestin_C; Arrestin (or S-antigen), C-terminal domain

pfam00339
Location:16 → 172

Arrestin_N; Arrestin (or S-antigen), N-terminal domain