ROGDI rogdi homolog (Drosophila) [Homo sapiens] - Gene

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Summary

Official Symbol: ROGDIprovided by HGNC
Official Full Name: rogdi homolog (Drosophila)provided by HGNC
Primary source: HGNC:29478
See related: Ensembl:ENSG00000067836; HPRD:13388; MIM:614574; Vega:OTTHUMG00000129479
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: KTZS; FLJ22386
Summary: This gene encodes a protein of unknown function. Loss-of-function mutation in this gene cause Kohlschutter-Tonz syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]

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Genomic context

Location :: 16p13.3

Sequence :: Chromosome: 16; NC_000016.9 (4846969..4852674, complement)

See ROGDI in Epigenomics, MapViewer

Chromosome 16 - NC_000016.9 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

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Phenotypes

Review eQTL and phenotype association data in this region using PheGenI

Products	Interactant	Other Gene	Source	Pubs	Description
Leucine zipper domain protein	Q7L5N1	COPS6	HPRD	PubMed
Leucine zipper domain protein	Q9P2H0	KIAA1377	HPRD	PubMed
BioGRID:122769	BioGRID:116176	COPS6	BioGRID	PubMed	Two-hybrid
BioGRID:122769	BioGRID:118061	DISC1	BioGRID	PubMed	Two-hybrid
BioGRID:122769	BioGRID:121617	KIAA1377	BioGRID	PubMed	Two-hybrid

Process	Evidence Code	Pubs
hemopoiesis	IEA Inferred from Electronic Annotation more info
positive regulation of cell proliferation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
intracellular	IDA Inferred from Direct Assay more info	PubMed

General protein information

Preferred Names: protein rogdi homolog

Names: protein rogdi homolog; leucine zipper domain protein

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NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

NG_032174.1 RefSeqGene

Range

5001..10989

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_024589.2 → NP_078865.1 protein rogdi homolog

Status: REVIEWED

Description

Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein.

Source sequence(s)

AA740842, AC020663, BC012901

Consensus CDS

CCDS10523.1

UniProtKB/Swiss-Prot

Q9GZN7

Related

ENSP00000322832, OTTHUMP00000159854, ENST00000322048, OTTHUMT00000251643

Conserved Domains (1) summary

pfam10259
Location:19 – 277
Blast Score: 663

Rogdi_lz; Rogdi leucine zipper containing protein

RNA

NR_046480.1 RNA Sequence

Description

Transcript Variant: This variant (2) lacks an internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

AA740842, AC020663, AK098348

RefSeqs of Annotated Genomes: Build 37.3

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh37.p5 Primary Assembly

Genomic

NC_000016.9 Reference GRCh37.p5 Primary Assembly

Range

4846969..4852674, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

AC_000148.1 Alternate HuRef

Range

4813167..4818872, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

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Related Sequences

Nucleotide		Protein
Heading	Accession and Version	Protein
genomic	AC020663.1 (89727..95710)	None
genomic	CH471112.2	EAW85258.1
		EAW85259.1
		EAW85260.1
		EAW85261.1
mRNA	AA740842.1	None
mRNA	AK026039.1	BAB15331.1
mRNA	AK054707.1	BAG51413.1
mRNA	AK098348.1	None
mRNA	AL136675.1	CAB66610.1
mRNA	BC012901.2	AAH12901.1
mRNA	CR457355.1	CAG33636.1
mRNA	CR533547.1	CAG38578.1
other-genetic	AM393155.1	CAL38033.1