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RNF26 ring finger protein 26 [ Homo sapiens (human) ]

Gene ID: 79102, updated on 8-May-2016
Official Symbol
RNF26provided by HGNC
Official Full Name
ring finger protein 26provided by HGNC
Primary source
HGNC:HGNC:14646
See related
Ensembl:ENSG00000173456 HPRD:05842; MIM:606130; Vega:OTTHUMG00000166171
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
The protein encoded by this intronless gene contains a C3HC5 type of RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. The expression of this gene was found to be upregulated in cancer cell lines derived from different types of cancer. [provided by RefSeq, Jul 2008]
Orthologs
Location:
11q23
Exon count:
1
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 11 NC_000011.10 (119334500..119337314)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (119205210..119208024)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene melanoma cell adhesion molecule Neighboring gene uncharacterized LOC105369590 Neighboring gene microRNA 6756 Neighboring gene C1q and tumor necrosis factor related protein 5 Neighboring gene membrane frizzled-related protein Neighboring gene ubiquitin specific peptidase 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Replication interactions

Interaction Pubs
Knockdown of ring finger protein 26 (RNF26) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells PubMed
Knockdown of ring finger protein 26 (RNF26) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells PubMed

Go to the HIV-1, Human Interaction Database

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC2642

Gene Ontology Provided by GOA

Function Evidence Code Pubs
zinc ion binding NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
RING finger protein 26
Names
ring finger protein with leucine zipper

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032015.4NP_114404.1  RING finger protein 26

    See identical proteins and their annotated locations for NP_114404.1

    Status: REVIEWED

    Source sequence(s)
    AP003396, CK821090
    Consensus CDS
    CCDS8419.1
    UniProtKB/Swiss-Prot
    Q9BY78
    Related
    ENSP00000312439, OTTHUMP00000232088, ENST00000311413, OTTHUMT00000388220
    Conserved Domains (1) summary
    cd00162
    Location:379425
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p2 Primary Assembly

    Range
    119334500..119337314
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018922.2 Alternate CHM1_1.1

    Range
    119091769..119094583
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)