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AHNAK AHNAK nucleoprotein [ Homo sapiens (human) ]

Gene ID: 79026, updated on 26-May-2016
Official Symbol
AHNAKprovided by HGNC
Official Full Name
AHNAK nucleoproteinprovided by HGNC
Primary source
HGNC:HGNC:347
See related
Ensembl:ENSG00000124942 HPRD:14684; MIM:103390; Vega:OTTHUMG00000167558
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AHNAKRS
Orthologs
Location:
11q12.2
Exon count:
9
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 11 NC_000011.10 (62433542..62546860, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (62201014..62314332, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene asparaginase like 1 Neighboring gene regulator of chromosome condensation 2 pseudogene 6 Neighboring gene uncharacterized LOC102723765 Neighboring gene uncharacterized LOC101929364 Neighboring gene secretoglobin family 1A member 1 Neighboring gene uncharacterized LOC101927617 Neighboring gene eukaryotic translation elongation factor 1 gamma Neighboring gene microRNA 6747 Neighboring gene terminal uridylyl transferase 1, U6 snRNA-specific

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.
NHGRI GWA Catalog
Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.
NHGRI GWA Catalog

Protein interactions

Protein Gene Interaction Pubs
Pr55(Gag) gag Cellular biotinylated neuroblast differentiation-associated protein AHNAK is incorporated into HIV-1 Gag virus-like particles PubMed

Go to the HIV-1, Human Interaction Database

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC5395

Gene Ontology Provided by GOA

Function Evidence Code Pubs
S100 protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
poly(A) RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
structural molecule activity conferring elasticity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
protein oligomerization ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
regulation of RNA splicing ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
regulation of voltage-gated calcium channel activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
T-tubule NAS
Non-traceable Author Statement
more info
PubMed 
actin cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
cell-cell contact zone IDA
Inferred from Direct Assay
more info
PubMed 
costamere ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
extracellular exosome IDA
Inferred from Direct Assay
more info
PubMed 
focal adhesion IDA
Inferred from Direct Assay
more info
PubMed 
lysosomal membrane IDA
Inferred from Direct Assay
more info
PubMed 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with membrane raft IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
nucleus NAS
Non-traceable Author Statement
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
sarcolemma IDA
Inferred from Direct Assay
more info
PubMed 
sarcolemma NAS
Non-traceable Author Statement
more info
PubMed 
vesicle IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
neuroblast differentiation-associated protein AHNAK
Names
AHNAK-related
desmoyokin

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001620.2NP_001611.1  neuroblast differentiation-associated protein AHNAK isoform 1

    See identical proteins and their annotated locations for NP_001611.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1, also known as L-AHNAK) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK300376, AP001363, BE873999, CB129722
    Consensus CDS
    CCDS31584.1
    UniProtKB/Swiss-Prot
    Q09666
    UniProtKB/TrEMBL
    B4DTV0
    Related
    ENSP00000367263, OTTHUMP00000236448, ENST00000378024, OTTHUMT00000395572
    Conserved Domains (2) summary
    COG2911
    Location:47265622
    TamB; Autotransporter translocation and assembly factor TamB [Intracellular trafficking, secretion, and vesicular transport]
    cl00117
    Location:2290
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
  2. NM_024060.3NP_076965.2  neuroblast differentiation-associated protein AHNAK isoform 2

    See identical proteins and their annotated locations for NP_076965.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2, also known as S-AHNAK) uses alternate 3' exons, compared to variant 1, resulting in a shorter isoform (2) with a unique C-terminus compared to isoform 1.
    Source sequence(s)
    BC000926, BC128460, CB129722, CN482151
    Consensus CDS
    CCDS44625.1
    UniProtKB/Swiss-Prot
    Q09666
    UniProtKB/TrEMBL
    Q9BVU3
    Related
    ENSP00000257247, OTTHUMP00000236155, ENST00000257247, OTTHUMT00000395014
    Conserved Domains (1) summary
    cl00117
    Location:2290
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p2 Primary Assembly

    Range
    62433542..62546860 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011545249.1XP_011543551.1  

    Conserved Domains (2) summary
    COG2911
    Location:45985494
    TamB; Autotransporter translocation and assembly factor TamB [Intracellular trafficking, secretion, and vesicular transport]
    cl00117
    Location:2290
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
  2. XM_005274242.1XP_005274299.1  

    Conserved Domains (2) summary
    COG2911
    Location:45985494
    TamB; Autotransporter translocation and assembly factor TamB [Intracellular trafficking, secretion, and vesicular transport]
    cl00117
    Location:2290
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
  3. XM_005274243.1XP_005274300.1  

    Conserved Domains (2) summary
    COG2911
    Location:45985494
    TamB; Autotransporter translocation and assembly factor TamB [Intracellular trafficking, secretion, and vesicular transport]
    cl00117
    Location:2290
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
  4. XM_011545250.1XP_011543552.1  

    Conserved Domains (2) summary
    COG2911
    Location:30484072
    TamB; Autotransporter translocation and assembly factor TamB [Intracellular trafficking, secretion, and vesicular transport]
    cl00117
    Location:2290
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
  5. XM_005274245.1XP_005274302.1  

    Conserved Domains (2) summary
    COG2911
    Location:41465170
    TamB; Autotransporter translocation and assembly factor TamB [Intracellular trafficking, secretion, and vesicular transport]
    cl00117
    Location:2290
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
  6. XM_005274244.1XP_005274301.1  

    Conserved Domains (2) summary
    COG2911
    Location:44705494
    TamB; Autotransporter translocation and assembly factor TamB [Intracellular trafficking, secretion, and vesicular transport]
    cl00117
    Location:2290
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
  7. XM_005274241.1XP_005274298.1  

    See identical proteins and their annotated locations for XP_005274298.1

    UniProtKB/Swiss-Prot
    Q09666
    Conserved Domains (2) summary
    COG2911
    Location:47265622
    TamB; Autotransporter translocation and assembly factor TamB [Intracellular trafficking, secretion, and vesicular transport]
    cl00117
    Location:2290
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
  8. XM_005274240.1XP_005274297.1  

    See identical proteins and their annotated locations for XP_005274297.1

    UniProtKB/Swiss-Prot
    Q09666
    Conserved Domains (2) summary
    COG2911
    Location:47265622
    TamB; Autotransporter translocation and assembly factor TamB [Intracellular trafficking, secretion, and vesicular transport]
    cl00117
    Location:2290
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

Alternate CHM1_1.1

Genomic

  1. NC_018922.2 Alternate CHM1_1.1

    Range
    62084072..62197372 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)