These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
Genomic
-
NG_017069.1 RefSeqGene
- Range
- 5000..16573
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001031717.3 → NP_001026887.1 cysteine-rich with EGF-like domain protein 1 isoform 1 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longer isoform (1).
- Source sequence(s)
-
AC018809, BC008720, BM674728
- Consensus CDS
-
CCDS33693.1
- UniProtKB/Swiss-Prot
-
Q96HD1
- Related
- ENSP00000321856, OTTHUMP00000207640, ENST00000326434, OTTHUMT00000339239
- Conserved Domains (3) summary
-
- cl00066
Location:210 – 245
Blast Score: 77
- FU; Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
- pfam11938
Location:46 – 143
Blast Score: 164
- DUF3456; TLR4 regulator and MIR-interacting MSAP
- cl09941
Location:305 – 336
Blast Score: 92
- EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
-
NM_001077415.2 → NP_001070883.1 cysteine-rich with EGF-like domain protein 1 isoform 2 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an exon in the 3' coding region, which results in a frameshift, compared to variant 1. The resulting protein (isoform 2) is shorter and has a distinct C-terminus, compared to isoform 1. Both variants 2 and 3 encode the same isoform (2)
- Source sequence(s)
-
AC018809, AF452623, BF182978, BM674728, DN996843
- Consensus CDS
-
CCDS2593.1
- UniProtKB/Swiss-Prot
-
Q96HD1
- Related
- ENSP00000393643, OTTHUMP00000207639, ENST00000452070, OTTHUMT00000339238
- Conserved Domains (3) summary
-
- cl00066
Location:210 – 245
Blast Score: 79
- FU; Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
- pfam11938
Location:46 – 143
Blast Score: 163
- DUF3456; TLR4 regulator and MIR-interacting MSAP
- cl09941
Location:305 – 336
Blast Score: 92
- EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
-
NM_015513.4 → NP_056328.2 cysteine-rich with EGF-like domain protein 1 isoform 2 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR and lacks an exon in the 3' coding region, which results in a frameshift, compared to variant 1. The resulting protein (isoform 2) is shorter and has a distinct C-terminus, compared to isoform 1. Both variants 2 and 3 encode the same isoform (2)
- Source sequence(s)
-
AC018809, AL050275, BM674728
- Consensus CDS
-
CCDS2593.1
- UniProtKB/Swiss-Prot
-
Q96HD1
- Related
- ENSP00000373322, OTTHUMP00000158826, ENST00000383811, OTTHUMT00000250533
- Conserved Domains (3) summary
-
- cl00066
Location:210 – 245
Blast Score: 79
- FU; Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
- pfam11938
Location:46 – 143
Blast Score: 163
- DUF3456; TLR4 regulator and MIR-interacting MSAP
- cl09941
Location:305 – 336
Blast Score: 92
- EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000003.11 Reference GRCh37.p5 Primary Assembly
- Range
- 9975524..9987097
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000135.1 Alternate HuRef
- Range
- 9911848..9923428
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)