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Stxbp5 syntaxin binding protein 5 (tomosyn) [ Mus musculus (house mouse) ]

Gene ID: 78808, updated on 8-May-2016
Official Symbol
Stxbp5provided by MGI
Official Full Name
syntaxin binding protein 5 (tomosyn)provided by MGI
Primary source
MGI:MGI:1926058
See related
Ensembl:ENSMUSG00000019790 Vega:OTTMUSG00000033369
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
LGL3; AW742610; mKIAA1006; 0710001E20Rik; 4930565N16Rik
Orthologs
Location:
10; 10 A2
Exon count:
29
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 10 NC_000076.6 (9755547..9901227, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (9475345..9620838, complement)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 31471 Neighboring gene TIP41, TOR signalling pathway regulator-like pseudogene Neighboring gene predicted gene 28905 Neighboring gene predicted gene, 31904

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Rab GTPase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
syntaxin binding IPI
Inferred from Physical Interaction
more info
PubMed 
syntaxin-1 binding IDA
Inferred from Direct Assay
more info
PubMed 
syntaxin-1 binding IPI
Inferred from Physical Interaction
more info
PubMed 
syntaxin-1 binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
axonogenesis TAS
Traceable Author Statement
more info
PubMed 
exocytosis IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of exocytosis IDA
Inferred from Direct Assay
more info
PubMed 
protein transport IEA
Inferred from Electronic Annotation
more info
 
regulation of blood coagulation ISO
Inferred from Sequence Orthology
more info
 
regulation of exocytosis IDA
Inferred from Direct Assay
more info
PubMed 
regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
regulation of protein secretion IBA
Inferred from Biological aspect of Ancestor
more info
 
transport IEA
Inferred from Electronic Annotation
more info
 
vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
SNARE complex IBA
Inferred from Biological aspect of Ancestor
more info
 
acetylcholine-gated channel complex IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
secretory granule IBA
Inferred from Biological aspect of Ancestor
more info
 
secretory granule NAS
Non-traceable Author Statement
more info
PubMed 
Preferred Names
syntaxin-binding protein 5
Names
lethal(2) giant larvae protein homolog 3
tomosyn 1
tomosyn-1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081344.2NP_001074813.2  syntaxin-binding protein 5

    Status: VALIDATED

    Source sequence(s)
    AC122390
    Consensus CDS
    CCDS35837.2
    UniProtKB/TrEMBL
    D3Z079
    Related
    ENSMUSP00000123253, OTTMUSP00000045052, ENSMUST00000141722, OTTMUST00000083764
    Conserved Domains (4) summary
    pfam08366
    Location:273385
    LLGL; LLGL2
    COG2319
    Location:47275
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:62280
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd15893
    Location:10491109
    R-SNARE_STXBP5; SNARE domain of STXBP5

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000076.6 Reference GRCm38.p3 C57BL/6J

    Range
    9755547..9901227 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006512927.2XP_006512990.1  

    Conserved Domains (4) summary
    pfam08366
    Location:273385
    LLGL; LLGL2
    COG2319
    Location:47275
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:62280
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd15893
    Location:10691129
    R-SNARE_STXBP5; SNARE domain of STXBP5
  2. XM_006512926.2XP_006512989.1  

    See identical proteins and their annotated locations for XP_006512989.1

    UniProtKB/Swiss-Prot
    Q8K400
    Related
    ENSMUSP00000044535, OTTMUSP00000045051, ENSMUST00000038213, OTTMUST00000083763
    Conserved Domains (4) summary
    pfam08366
    Location:273385
    LLGL; LLGL2
    COG2319
    Location:47275
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:62280
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd15893
    Location:10851145
    R-SNARE_STXBP5; SNARE domain of STXBP5
  3. XM_006512928.2XP_006512991.1  

    UniProtKB/TrEMBL
    D3Z2Q2
    Related
    ENSMUSP00000121507, OTTMUSP00000045053, ENSMUST00000125200, OTTMUST00000083765
    Conserved Domains (4) summary
    pfam08366
    Location:273385
    LLGL; LLGL2
    COG2319
    Location:47275
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:62280
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd15893
    Location:10321092
    R-SNARE_STXBP5; SNARE domain of STXBP5
  4. XM_006512929.2XP_006512992.1  

    Conserved Domains (3) summary
    pfam08366
    Location:273385
    LLGL; LLGL2
    COG2319
    Location:65275
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:62280
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  5. XM_011243236.1XP_011241538.1  

    Conserved Domains (3) summary
    pfam08366
    Location:273385
    LLGL; LLGL2
    COG2319
    Location:65275
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:62280
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  6. XM_011243237.1XP_011241539.1  

    Conserved Domains (3) summary
    pfam08366
    Location:273385
    LLGL; LLGL2
    COG2319
    Location:65275
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:62280
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  7. XM_011243238.1XP_011241540.1  

    Conserved Domains (3) summary
    pfam08366
    Location:273385
    LLGL; LLGL2
    COG2319
    Location:47275
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:62280
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RNA

  1. XR_380092.2 RNA Sequence

  2. XR_380094.2 RNA Sequence

  3. XR_380096.2 RNA Sequence

Alternate Mm_Celera

Genomic

  1. AC_000032.1 Alternate Mm_Celera

    Range
    9659963..9805506 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_030191.1: Suppressed sequence

    Description
    NM_030191.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.