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SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 [ Bos taurus (cattle) ]

Gene ID: 781282, updated on 5-Mar-2024

Summary

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Official Symbol
SVEP1provided by VGNC
Official Full Name
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1provided by VGNC
Primary source
VGNC:VGNC:56985
See related
Ensembl:ENSBTAG00000020243
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
48
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 8 NC_037335.1 (99898020..100106648, complement)

Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132346006 Neighboring gene thioredoxin Neighboring gene thioredoxin domain containing 8 Neighboring gene uncharacterized LOC132346007 Neighboring gene muscle associated receptor tyrosine kinase Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene lysophosphatidic acid receptor 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of complement activation, classical pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037335.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    99898020..100106648 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010808239.4 → XP_010806541.2  sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1

    UniProtKB/TrEMBL
    F1MNH3
    Related
    ENSBTAP00000001939.7, ENSBTAT00000001939.7
    Conserved Domains (11) summary
    cd00033
    Location:440 → 496
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00032
    Location:1691 → 1744
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    smart00179
    Location:1746 → 1784
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:1232 → 1268
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam02494
    Location:562 → 644
    HYR; HYR domain
    pfam00084
    Location:1629 → 1686
    Sushi; Sushi repeat (SCR repeat)
    pfam00092
    Location:86 → 260
    VWA; von Willebrand factor type A domain
    pfam07699
    Location:1114 → 1161
    Ephrin_rec_like; Putative ephrin-receptor like
    cl03620
    Location:670 → 724
    DUF5011; Domain of unknown function (DUF5011)
    cl22861
    Location:1420 → 1622
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cl27761
    Location:1790 → 2018
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
Nucleotide Protein Strain
Heading Accession and Version

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