pykA-2 pyruvate kinase [Vibrio cholerae M66-2] - Gene

Summary

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Gene symbol: pykA-2
Gene description: pyruvate kinase
Locus tag: VCM66_A0666
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Vibrio cholerae M66-2 (strain: M66-2, serotype: O1)
Lineage: Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio

Genomic context

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Location :: country: Indonesia: Makassar, other: 1937, chromosome: II

Sequence :: Chromosome: II; NC_012580.1 (625258..626718)

Chromosome II - NC_012580.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence

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Bibliography

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GeneRIFs: Gene References Into Functions What's a GeneRIF?

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Pathways from BioSystems

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Adenine ribonucleotide biosynthesis, IMP => ADP,ATP, organism-specific biosystem (from KEGG)
Adenine ribonucleotide biosynthesis, IMP => ADP,ATP, organism-specific biosystemPathway module; Nucleotide and amino acid metabolism; Purine metabolism
Adenine ribonucleotide biosynthesis, IMP => ADP,ATP, conserved biosystem (from KEGG)
Adenine ribonucleotide biosynthesis, IMP => ADP,ATP, conserved biosystemPathway module; Nucleotide and amino acid metabolism; Purine metabolism
Biosynthesis of amino acids, organism-specific biosystem (from KEGG)
Biosynthesis of amino acids, organism-specific biosystem
Biosynthesis of amino acids
Biosynthesis of amino acids, conserved biosystem (from KEGG)
Biosynthesis of amino acids, conserved biosystem
Biosynthesis of amino acids
Biosynthesis of secondary metabolites, organism-specific biosystem (from KEGG)
Biosynthesis of secondary metabolites, organism-specific biosystem
Biosynthesis of secondary metabolites
Glycolysis / Gluconeogenesis, organism-specific biosystem (from KEGG)
Glycolysis / Gluconeogenesis, organism-specific biosystemGlycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabol...
Glycolysis / Gluconeogenesis, conserved biosystem (from KEGG)
Glycolysis / Gluconeogenesis, conserved biosystemGlycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabol...
Glycolysis, core module involving three-carbon compounds, organism-specific biosystem (from KEGG)
Glycolysis, core module involving three-carbon compounds, organism-specific biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Glycolysis, core module involving three-carbon compounds, conserved biosystem (from KEGG)
Glycolysis, core module involving three-carbon compounds, conserved biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Guanine ribonucleotide biosynthesis IMP => GDP,GTP, organism-specific biosystem (from KEGG)
Guanine ribonucleotide biosynthesis IMP => GDP,GTP, organism-specific biosystemPathway module; Nucleotide and amino acid metabolism; Purine metabolism
Guanine ribonucleotide biosynthesis IMP => GDP,GTP, conserved biosystem (from KEGG)
Guanine ribonucleotide biosynthesis IMP => GDP,GTP, conserved biosystemPathway module; Nucleotide and amino acid metabolism; Purine metabolism
Microbial metabolism in diverse environments, organism-specific biosystem (from KEGG)
Microbial metabolism in diverse environments, organism-specific biosystem
Microbial metabolism in diverse environments
Purine metabolism, organism-specific biosystem (from KEGG)
Purine metabolism, organism-specific biosystem
Purine metabolism
Purine metabolism, conserved biosystem (from KEGG)
Purine metabolism, conserved biosystem
Purine metabolism
Pyruvate metabolism, organism-specific biosystem (from KEGG)
Pyruvate metabolism, organism-specific biosystem
Pyruvate metabolism
Pyruvate metabolism, conserved biosystem (from KEGG)
Pyruvate metabolism, conserved biosystem
Pyruvate metabolism

General gene information

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General protein information

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Names: pyruvate kinase

YP_002812285.1

EC 2.7.1.4

catalyzes the formation of phosphoenolpyruvate from pyruvate

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_012580.1

Range

625258..626718

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

YP_002812285.1 pyruvate kinase II [Vibrio cholerae M66-2]

Status: PROVISIONAL

UniProtKB/TrEMBL

C3LVX3

Conserved Domains (2) summary

PRK05826
Location:1 – 468
Blast Score: 1677

PRK05826; pyruvate kinase; Provisional

cl17342
Location:3 – 476
Blast Score: 1208

Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...