Ulbp1 UL16 binding protein 1 [Mus musculus] - Gene

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Summary

Official Symbol: Ulbp1provided by MGI
Official Full Name: UL16 binding protein 1provided by MGI
Primary source: MGI:1925027
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: MULT1; A430108B07Rik
Annotation information: Annotation category: suggests misassembly

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Genomic context

Location :: 10 A3; 10

Sequence :: Chromosome: 10; NC_000076.6 (7444873..7473477, complement)

See Ulbp1 in Epigenomics, MapViewer

Chromosome 10 - NC_000076.6 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results identify Mult1 as a target for the MARCH family of E3 ligases
Title: Stress-regulated targeting of the NKG2D ligand Mult1 by a membrane-associated RING-CH family E3 ligase.
Mouse cytomegalovirus (MCMV) molecule fcr-1 promotes a rapid down-regulation of NKG2D ligands murine UL16-binding protein like transcript (MULT)-1 and H60 from the cell surface.
Title: The herpesviral Fc receptor fcr-1 down-regulates the NKG2D ligands MULT-1 and H60.
MULT1 (UL16-binding protein-like transcript 1) is expressed in adult parenchyma, possesses MHC class I-like alpha 1 and alpha 2 domains and a large cytoplasmic domain, and binds NKG2D with high affinity. (MULT1)
Title: Cutting edge: murine UL16-binding protein-like transcript 1: a newly described transcript encoding a high-affinity ligand for murine NKG2D.

Submit: New GeneRIF Correction

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description
BioGRID:218913	BioGRID:113164	UBC		BioGRID	PubMed	Affinity Capture-Western

Function	Evidence Code	Pubs
natural killer cell lectin-like receptor binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
positive regulation of immune response to tumor cell	IDA Inferred from Direct Assay more info	PubMed
positive regulation of interferon-gamma production	IDA Inferred from Direct Assay more info	PubMed
positive regulation of macrophage activation	IDA Inferred from Direct Assay more info	PubMed
positive regulation of natural killer cell activation	IDA Inferred from Direct Assay more info	PubMed
positive regulation of nitric oxide biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
susceptibility to natural killer cell mediated cytotoxicity	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
external side of plasma membrane	IDA Inferred from Direct Assay more info	PubMed
integral to plasma membrane	IDA Inferred from Direct Assay more info	PubMed

General protein information

Preferred Names: NKG2D ligand 1

Names: NKG2D ligand 1; UL16-binding protein-like transcript 1

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NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_029975.2 → NP_084251.1 NKG2D ligand 1 precursor

Status: PROVISIONAL

Source sequence(s)

BC132072

UniProtKB/TrEMBL

Q8HWA3

RefSeqs of Annotated Genomes: Build 38.1

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38 C57BL/6J

Genomic

NC_000076.6 Reference GRCm38 C57BL/6J

Range

7444873..7473477, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

AC_000032.1 Alternate Mm_Celera

Range

7404171..7432757, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

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Related Sequences

Nucleotide		Protein	Strain
Heading	Accession and Version	Protein	Strain
genomic	AC159136.7	None
genomic	AC170753.7 (149943..178872)	None
genomic	CH466562.2	EDL03554.1	mixed
		EDL03555.1	mixed
mRNA	AK020784.1	BAB32211.1	C57BL/6J
mRNA	AK037408.1	None	C57BL/6J
mRNA	AK084712.1	BAC39260.1	C57BL/6J
mRNA	AK085119.1	None	C57BL/6J
mRNA	AY249021.1	AAP76223.1	C57BL/6
mRNA	BC104292.1	AAI04293.1
mRNA	BC104293.1	AAI04294.1
mRNA	BC114390.1	AAI14391.1
mRNA	BC114420.1	AAI14421.1
mRNA	BC127022.1	AAI27023.1
mRNA	BC127023.1	AAI27024.1
mRNA	BC132070.1	AAI32071.1
mRNA	BC132072.1	AAI32073.1
mRNA	EU047812.1	ABW08107.1	BALB/c

Protein Accession	Links
Protein Accession	GenPept Link	UniProtKB Link
Q330P3	GenPept	UniProtKB/TrEMBL:Q330P3
Q3MI26	GenPept	UniProtKB/TrEMBL:Q3MI26
Q8HWA3	GenPept	UniProtKB/TrEMBL:Q8HWA3
Q9D205	GenPept	UniProtKB/TrEMBL:Q9D205