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Msi2 musashi RNA-binding protein 2 [ Mus musculus (house mouse) ]

Gene ID: 76626, updated on 10-May-2016
Official Symbol
Msi2provided by MGI
Official Full Name
musashi RNA-binding protein 2provided by MGI
Primary source
MGI:MGI:1923876
See related
Ensembl:ENSMUSG00000069769 Vega:OTTMUSG00000008130
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Msi2h; AI451722; AI563628; AW489193; 1700105C15Rik
Orthologs
Location:
11; 11 C
Exon count:
21
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 11 NC_000077.6 (88339382..88718267, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (88152884..88403661, complement)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 34366 Neighboring gene coiled-coil domain containing 182 Neighboring gene microRNA 378b Neighboring gene ribosomal protein L35A pseudogene Neighboring gene RIKEN cDNA 0610039H22 gene Neighboring gene RIKEN cDNA C030037D09 gene Neighboring gene RIKEN cDNA 4930556N13 gene Neighboring gene A kinase (PRKA) anchor protein 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • mRNA processing, organism-specific biosystem (from WikiPathways)
    mRNA processing, organism-specific biosystemAdapted from Reactome, see: [http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_1675.1 REACT 1675.1] This process describes the conversion of precursor messenger RNA into mature messenge...
  • mRNA surveillance pathway, organism-specific biosystem (from KEGG)
    mRNA surveillance pathway, organism-specific biosystemThe mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go ...
  • mRNA surveillance pathway, conserved biosystem (from KEGG)
    mRNA surveillance pathway, conserved biosystemThe mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go ...

Markers

Homology

Clone Names

  • MGC118040, MGC130496

Gene Ontology Provided by MGI

Function Evidence Code Pubs
RNA binding IEA
Inferred from Electronic Annotation
more info
 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
poly(U) RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
single-stranded RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
stem cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
polysome IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
RNA-binding protein Musashi homolog 2
Names
Musashi2
musashi-2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001201341.1NP_001188270.1  RNA-binding protein Musashi homolog 2 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) represents an alternate splice pattern in the 3' coding region and UTR, compared to variant 1. The resulting isoform (2) has a substantially shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AL645601
    Consensus CDS
    CCDS48882.1
    UniProtKB/TrEMBL
    B1AT13
    Related
    ENSMUSP00000103541, OTTMUSP00000008491, ENSMUST00000107908, OTTMUST00000018478
    Conserved Domains (2) summary
    smart00360
    Location:2292
    RRM; RNA recognition motif
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  2. NM_054043.3NP_473384.1  RNA-binding protein Musashi homolog 2 isoform 1

    See identical proteins and their annotated locations for NP_473384.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    BK001483, BQ174763
    Consensus CDS
    CCDS56796.1
    UniProtKB/Swiss-Prot
    Q920Q6
    UniProtKB/TrEMBL
    Q3TE41
    Related
    ENSMUSP00000090470, OTTMUSP00000008492, ENSMUST00000092794, OTTMUST00000018479
    Conserved Domains (3) summary
    smart00360
    Location:111182
    RRM; RNA recognition motif
    cd12323
    Location:111184
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p3 C57BL/6J

    Range
    88339382..88718267 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006534442.2XP_006534505.1  

    See identical proteins and their annotated locations for XP_006534505.1

    UniProtKB/Swiss-Prot
    Q920Q6
    UniProtKB/TrEMBL
    Q2M2Q8
    Related
    ENSMUSP00000103542, OTTMUSP00000008489, ENSMUST00000107909, OTTMUST00000018474
    Conserved Domains (3) summary
    smart00360
    Location:111182
    RRM; RNA recognition motif
    cd12323
    Location:111184
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  2. XM_011249302.1XP_011247604.1  

    See identical proteins and their annotated locations for XP_011247604.1

    Conserved Domains (3) summary
    smart00360
    Location:111182
    RRM; RNA recognition motif
    cd12323
    Location:111184
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  3. XM_006534440.2XP_006534503.1  

    Conserved Domains (3) summary
    smart00360
    Location:135206
    RRM; RNA recognition motif
    cd12323
    Location:135208
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  4. XM_006534434.2XP_006534497.1  

    Conserved Domains (3) summary
    smart00360
    Location:135206
    RRM; RNA recognition motif
    cd12323
    Location:135208
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  5. XM_006534435.2XP_006534498.1  

    Conserved Domains (3) summary
    smart00360
    Location:135206
    RRM; RNA recognition motif
    cd12323
    Location:135208
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  6. XM_006534438.2XP_006534501.1  

    Conserved Domains (3) summary
    smart00360
    Location:135206
    RRM; RNA recognition motif
    cd12323
    Location:135208
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  7. XM_006534439.2XP_006534502.1  

    Conserved Domains (3) summary
    smart00360
    Location:135206
    RRM; RNA recognition motif
    cd12323
    Location:135208
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  8. XM_006534431.2XP_006534494.1  

    Conserved Domains (3) summary
    smart00360
    Location:135206
    RRM; RNA recognition motif
    cd12323
    Location:135208
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  9. XM_006534432.2XP_006534495.1  

    Conserved Domains (3) summary
    smart00360
    Location:135206
    RRM; RNA recognition motif
    cd12323
    Location:135208
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  10. XM_006534441.2XP_006534504.1  

    Conserved Domains (3) summary
    smart00360
    Location:135206
    RRM; RNA recognition motif
    cd12323
    Location:135208
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  11. XM_011249303.1XP_011247605.1  

    See identical proteins and their annotated locations for XP_011247605.1

    Conserved Domains (3) summary
    smart00360
    Location:107178
    RRM; RNA recognition motif
    cd12323
    Location:107180
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:1993
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  12. XM_011249305.1XP_011247607.1  

    See identical proteins and their annotated locations for XP_011247607.1

    Conserved Domains (2) summary
    smart00360
    Location:2697
    RRM; RNA recognition motif
    cd12323
    Location:2699
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
  13. XM_006534443.2XP_006534506.1  

    Conserved Domains (3) summary
    smart00360
    Location:135206
    RRM; RNA recognition motif
    cd12323
    Location:135208
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  14. XM_011249304.1XP_011247606.1  

    Conserved Domains (3) summary
    smart00360
    Location:135206
    RRM; RNA recognition motif
    cd12323
    Location:135208
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins

RNA

  1. XR_879764.1 RNA Sequence

  2. XR_388550.2 RNA Sequence

Reference GRCm38.p3 NOD/ShiLtJ

Genomic

  1. NT_187003.1 Reference GRCm38.p3 NOD/ShiLtJ

    Range
    1483786..1862559 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006536469.1XP_006536532.1  

    See identical proteins and their annotated locations for XP_006536532.1

    UniProtKB/Swiss-Prot
    Q920Q6
    UniProtKB/TrEMBL
    Q2M2Q8
    Conserved Domains (3) summary
    smart00360
    Location:111182
    RRM; RNA recognition motif
    cd12323
    Location:111184
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  2. XM_011251962.1XP_011250264.1  

    Conserved Domains (3) summary
    smart00360
    Location:111182
    RRM; RNA recognition motif
    cd12323
    Location:111184
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  3. XM_011251959.1XP_011250261.1  

    Conserved Domains (3) summary
    smart00360
    Location:111182
    RRM; RNA recognition motif
    cd12323
    Location:111184
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  4. XM_011251949.1XP_011250251.1  

    See identical proteins and their annotated locations for XP_011250251.1

    Conserved Domains (3) summary
    smart00360
    Location:111182
    RRM; RNA recognition motif
    cd12323
    Location:111184
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  5. XM_011251969.1XP_011250271.1  

    Conserved Domains (3) summary
    smart00360
    Location:111182
    RRM; RNA recognition motif
    cd12323
    Location:111184
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  6. XM_011251961.1XP_011250263.1  

    See identical proteins and their annotated locations for XP_011250263.1

    Conserved Domains (3) summary
    smart00360
    Location:107178
    RRM; RNA recognition motif
    cd12323
    Location:107180
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:1993
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  7. XM_011251970.1XP_011250272.1  

    See identical proteins and their annotated locations for XP_011250272.1

    Conserved Domains (2) summary
    smart00360
    Location:2697
    RRM; RNA recognition motif
    cd12323
    Location:2699
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
  8. XM_011251972.1XP_011250274.1  

    Conserved Domains (2) summary
    smart00360
    Location:1662
    RRM; RNA recognition motif
    cl17169
    Location:1664
    RRM_SF; RNA recognition motif (RRM) superfamily
  9. XM_006536464.2XP_006536527.2  

    Conserved Domains (3) summary
    smart00360
    Location:111182
    RRM; RNA recognition motif
    cd12323
    Location:111184
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  10. XM_011251971.1XP_011250273.1  

    Conserved Domains (3) summary
    smart00360
    Location:111182
    RRM; RNA recognition motif
    cd12323
    Location:111184
    RRM2_MSI; RNA recognition motif 2 in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  11. XM_011251978.1XP_011250280.1  

    See identical proteins and their annotated locations for XP_011250280.1

    UniProtKB/TrEMBL
    Q32LZ4
    Conserved Domains (2) summary
    smart00360
    Location:2292
    RRM; RNA recognition motif
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins
  12. XM_011251973.1XP_011250275.1  

    Conserved Domains (2) summary
    smart00360
    Location:2292
    RRM; RNA recognition motif
    cd12576
    Location:2397
    RRM1_MSI; RNA recognition motif 1 in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins

RNA

  1. XR_888314.1 RNA Sequence

Alternate Mm_Celera

Genomic

  1. AC_000033.1 Alternate Mm_Celera

    Range
    97951761..98327494 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)