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ugt5c2 UDP glucuronosyltransferase 5 family, polypeptide C2 [ Danio rerio (zebrafish) ]

Gene ID: 751669, updated on 27-Mar-2024

Summary

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Official Symbol
ugt5c2provided by ZNC
Official Full Name
UDP glucuronosyltransferase 5 family, polypeptide C2provided by ZNC
Primary source
ZFIN:ZDB-GENE-060825-206
See related
Ensembl:ENSDARG00000006372 AllianceGenome:ZFIN:ZDB-GENE-060825-206
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:153270; si:ch211-278n20.5
Summary
Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in eye; female organism; liver; male organism; and pleuroperitoneal region. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 18
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (40447447..40469536)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (40472253..40479338)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108180041 Neighboring gene semaphorin 6D Neighboring gene UDP glucuronosyltransferase 5 family, polypeptide C1 Neighboring gene zgc:101040 Neighboring gene UDP glucuronosyltransferase 5 family, polypeptide C3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Tissue-, sex- and development-specific transcription profiles of eight UDP-glucuronosyltransferase genes in zebrafish (Danio rerio) and their regulation by activator of aryl hydrocarbon receptor. Christen V, et al. Aquat Toxicol, 2014 May. PMID 24667232
  2. Characterization of the zebrafish Ugt repertoire reveals a new class of drug-metabolizing UDP glucuronosyltransferases. Wang Y, et al. Mol Pharmacol, 2014 Jul. PMID 24728488
  3. Cloning and comparative analyses of the zebrafish Ugt repertoire reveal its evolutionary diversity. Huang H, et al. PLoS One, 2010 Feb 10. PMID 20161780, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC153270

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP-glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glucuronosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
UDP glucuronosyltransferase 5 family, polypeptide C2
NP_001038851.1
XP_021323379.1
XP_021323380.1
XP_021323381.1
XP_021323382.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045386.1 → NP_001038851.1  UDP glucuronosyltransferase 5 family, polypeptide C2

    See identical proteins and their annotated locations for NP_001038851.1

    Status: PROVISIONAL

    Source sequence(s)
    BC122216
    UniProtKB/TrEMBL
    B2GQB2, F6NXG7, Q0P492
    Related
    ENSDARP00000082079.4, ENSDART00000087645.5
    Conserved Domains (2) summary
    PHA03392
    Location:288 → 528
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:49 → 551
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    40447447..40469536
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021467705.1 → XP_021323380.1  UDP glucuronosyltransferase 5 family, polypeptide C2 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PQD9
    Conserved Domains (1) summary
    pfam00201
    Location:43 → 545
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

  2. XM_021467707.1 → XP_021323382.1  UDP glucuronosyltransferase 5 family, polypeptide C2 isoform X4

    UniProtKB/TrEMBL
    A0A8M9P163
    Related
    ENSDARP00000082081.4, ENSDART00000087647.5
    Conserved Domains (1) summary
    pfam00201
    Location:28 → 530
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

  3. XM_021467704.1 → XP_021323379.1  UDP glucuronosyltransferase 5 family, polypeptide C2 isoform X1

    UniProtKB/TrEMBL
    A0A8M9PFK2
    Conserved Domains (1) summary
    pfam00201
    Location:43 → 545
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

  4. XM_021467706.1 → XP_021323381.1  UDP glucuronosyltransferase 5 family, polypeptide C2 isoform X3

    UniProtKB/TrEMBL
    A0A8M9PMA0
    Conserved Domains (1) summary
    pfam00201
    Location:34 → 536
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
Nucleotide Protein Strain
Heading Accession and Version

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