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Klrg2 killer cell lectin-like receptor subfamily G, member 2 [ Mus musculus (house mouse) ]

Gene ID: 74253, updated on 5-Mar-2024

Summary

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Official Symbol
Klrg2provided by MGI
Official Full Name
killer cell lectin-like receptor subfamily G, member 2provided by MGI
Primary source
MGI:MGI:1921503
See related
Ensembl:ENSMUSG00000071537 AllianceGenome:MGI:1921503
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2310020F24Rik
Summary
Predicted to enable carbohydrate binding activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human KLRG2 (killer cell lectin like receptor G2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in stomach adult (RPKM 6.9), genital fat pad adult (RPKM 3.0) and 7 other tissues See more
Orthologs
human all
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Genomic context

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Location:
6 B1; 6 17.85 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (38593264..38615750, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (38616329..38638815, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:38484704-38484891 Neighboring gene STARR-positive B cell enhancer ABC_E2782 Neighboring gene kinesin family member 11 pseudogene Neighboring gene formation of mitochondrial complex V assembly factor 1 Neighboring gene LUC7-like 2 (S. cerevisiae) Neighboring gene Clec2l Hedgehog-responsive enhancer Neighboring gene C-type lectin domain family 2, member L Neighboring gene homeodomain interacting protein kinase 2 Neighboring gene predicted gene, 53285

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
killer cell lectin-like receptor subfamily G member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033171.2 → NP_001028343.2  killer cell lectin-like receptor subfamily G member 2

    See identical proteins and their annotated locations for NP_001028343.2

    Status: VALIDATED

    Source sequence(s)
    AC161147, AK009417
    Consensus CDS
    CCDS20016.1
    UniProtKB/Swiss-Prot
    Q3TE30, Q3UM83
    UniProtKB/TrEMBL
    G5E8L6
    Related
    ENSMUSP00000093732.4, ENSMUST00000096030.7
    Conserved Domains (1) summary
    cd03593
    Location:271 → 382
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    38593264..38615750 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506711.4 → XP_006506774.1  killer cell lectin-like receptor subfamily G member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q3TE30, Q3UM83
    Conserved Domains (2) summary
    PHA03247
    Location:4 → 197
    PHA03247; large tegument protein UL36; Provisional
    cl02432
    Location:271 → 350
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3UM83.1 GenPept UniProtKB/Swiss-Prot:Q3UM83

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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