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    Gtf2e1 general transcription factor II E, polypeptide 1 (alpha subunit) [ Mus musculus (house mouse) ]

    Gene ID: 74197, updated on 11-May-2013
    Official Symbol
    Gtf2e1provided by MGI
    Official Full Name
    general transcription factor II E, polypeptide 1 (alpha subunit)provided by MGI
    Primary source
    MGI:1921447
    See related
    Ensembl:ENSMUSG00000022828; Vega:OTTMUSG00000025449
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    FE; 56kDa; TFIIE-A; AI303800; 2610024P03Rik
    Location :
    16 B3; 16
    Sequence :
    Chromosome: 16; NC_000082.6 (37509796..37539769, complement)
    See Gtf2e1 in Epigenomics, MapViewer

    Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene polymerase (DNA directed), theta Neighboring gene syntaxin binding protein 5-like Neighboring gene LIM and senescent cell antigen like domains 2 pseudogene Neighboring gene RAB, member of RAS oncogene family-like 3 Neighboring gene homogentisate 1, 2-dioxygenase

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. Transcription factor Foxp3 and its protein partners form a complex regulatory network. Rudra D, et al. Nat Immunol, 2012 Oct. PMID 22922362.
    2. Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria. Kamileri I, et al. Proc Natl Acad Sci U S A, 2012 Feb 21. PMID 22323595.
    3. Oct4 links multiple epigenetic pathways to the pluripotency network. Ding J, et al. Cell Res, 2012 Jan. PMID 22083510.
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750.
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068.

    See all (26) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:216568 BioGRID:198663 Cdx1    BioGRID  PubMed Two-hybrid 
    BioGRID:216568 BioGRID:203183 Foxp3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:216568 BioGRID:212686 Gtf2e2    BioGRID  PubMed Two-hybrid 
    BioGRID:216568 BioGRID:205138 Mixl1    BioGRID  PubMed Two-hybrid 
    BioGRID:216568 BioGRID:201709 Ncoa3    BioGRID  PubMed Two-hybrid 
    BioGRID:216568 BioGRID:201742 Nfe2    BioGRID  PubMed Two-hybrid 
    BioGRID:216568 BioGRID:206153 Olig1    BioGRID  PubMed Two-hybrid 
    BioGRID:216568 BioGRID:202265 Pml    BioGRID  PubMed Two-hybrid 
    BioGRID:216568 BioGRID:202313 Pou5f1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:216568 BioGRID:231054 Tardbp    BioGRID  PubMed Two-hybrid 
    BioGRID:216568 BioGRID:214963 Zbtb43    BioGRID  PubMed Two-hybrid 
    BioGRID:216568 BioGRID:243089 Zbtb9    BioGRID  PubMed Two-hybrid 

    Markers

    Genotypes

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    molecular_function ND
    No biological Data available
    more info
    		  
    sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    regulation of transcription, DNA-dependent IEA
    Inferred from Electronic Annotation
    more info
    		  
    transcription initiation from RNA polymerase II promoter IEA
    Inferred from Electronic Annotation
    more info
    		  
    transcription, DNA-dependent IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Preferred Names
    general transcription factor IIE subunit 1
    Names
    general transcription factor IIE subunit 1
    TFIIE-alpha
    general transcription factor IIE 56 kDa subunit
    transcription initiation factor IIE subunit alpha
    general transcription factor IIE, polypeptide 1 (alpha subunit, 56kDa)
    general transcription factor II E, polypeptide 1 (alpha subunit, 56kDa)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028812.3 → NP_083088.1  general transcription factor IIE subunit 1

      Status: PROVISIONAL

      Source sequence(s)
      AC154762
      Consensus CDS
      CCDS28160.1
      UniProtKB/Swiss-Prot
      Q9D0D5
      Related
      ENSMUSP00000023525, OTTMUSP00000030935, ENSMUST00000023525, OTTMUST00000062666
      Conserved Domains (4) summary
      smart00531
      Location:28 – 175
      Blast Score: 482
      TFIIE; Transcription initiation factor IIE
      pfam02002
      Location:16 – 123
      Blast Score: 336
      TFIIE_alpha; TFIIE alpha subunit
      pfam11521
      Location:395 – 440
      Blast Score: 211
      TFIIE-A_C-term; C-terminal general transcription factor TFIIE alpha
      pfam08271
      Location:127 – 169
      Blast Score: 91
      TF_Zn_Ribbon; TFIIB zinc-binding

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 103

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p1 C57BL/6J

    Genomic

    1. NC_000082.6 Reference GRCm38.p1 C57BL/6J

      Range
      37509796..37539769, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000038.1 Alternate Mm_Celera

      Range
      37917704..37947677, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    genomic AAHY01127113.1 (49246..79219) None
    genomic AC154762.2 (25194..55168) None
    genomic CH466521.1 EDK97958.1 mixed
    mRNA AK011543.1 BAB27686.1 C57BL/6J
    mRNA AK031528.1 BAC27436.1 C57BL/6J
    mRNA AK080478.1 BAC37928.1 C57BL/6J
    mRNA AK084978.1 None C57BL/6J
    mRNA AK154283.1 BAE32487.1 NOD
    mRNA BC056966.1 AAH56966.1 C57BL/6
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D0D5.1 GenPept UniProtKB/Swiss-Prot:Q9D0D5

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

      Table of contents

      Related information

      • Order cDNA clone
        Order cDNA clone
      • BioProjects
        BioProjects related to a gene
      • BioSystems
        BioSystems
      • CCDS
        Links from Gene to CCDS are established if a gene encodes a protein sequence that is a member of a Consensus CDS (CCDS).
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • dbVar
        Link from Gene to dbVar
      • Full text in PMC
        PMC links
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • GEO Profiles
        Related GEO
      • HomoloGene
        Links between HomoloGene and Gene are provided by the HomoloGene group when a gene is included in a HomoloGene record.
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubChem Compound
        PubChem Compounds
      • PubChem Substance
        PubChem Substances
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed (GeneRIF)
        GeneRIF -- Gene Reference Into Function Staff of the Index Section in the National Library of Medicine review the current literature. When they find articles focused on the structure and function of a gene, they write a brief summary of the impact of the paper and make the connection between the citation (PubMed) and Gene. An interface exists for interested users to submit such data as well. http://www.ncbi.nlm.nih.gov/projects/GeneRIF/GeneRIFhelp.html
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • SNP
        Related SNP records
      • SNP: GeneView
        SNPs linked from GeneView
      • SNP: Genotype
        Gene Genotype Report
      • Taxonomy
        Link to related taxonomy entry
      • UniGene
        Links are provided between Gene and UniGene when both databases calculate links to the same mRNA record (gi).
      • UniSTS
        Related UniSTS records

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