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KDM6A lysine demethylase 6A [ Homo sapiens (human) ]

Gene ID: 7403, updated on 22-May-2016
Official Symbol
KDM6Aprovided by HGNC
Official Full Name
lysine demethylase 6Aprovided by HGNC
Primary source
HGNC:HGNC:12637
See related
Ensembl:ENSG00000147050 HPRD:02131; MIM:300128; Vega:OTTHUMG00000021402
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
UTX; KABUK2; bA386N14.2
Summary
This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]
Orthologs
Location:
Xp11.2
Exon count:
32
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) X NC_000023.11 (44873175..45112779)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (44732419..44972024)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373190 Neighboring gene dual specificity phosphatase 21 Neighboring gene chromosome X open reading frame 36 Neighboring gene uncharacterized LOC105373191

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Associated conditions

Description Tests
Kabuki make-up syndrome
MedGen: C0796004 OMIM: 147920 GeneReviews: Kabuki Syndrome
Compare labs
Kabuki syndrome 2
MedGen: C3275495 OMIM: 300867 GeneReviews: Not available
Compare labs

Copy number response

Description
Copy number response
Triplosensitivity

No evidence available (Last evaluated (2013-07-18)

ClinGen Genome Curation Page
Haploinsufficency

Sufficient evidence for dosage pathogenicity (Last evaluated (2013-07-18)

ClinGen Genome Curation PagePubMed
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC141941, DKFZp686A03225

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA polymerase II core promoter proximal region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
chromatin DNA binding IEA
Inferred from Electronic Annotation
more info
 
dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 
histone demethylase activity TAS
Traceable Author Statement
more info
 
histone demethylase activity (H3-K27 specific) IEA
Inferred from Electronic Annotation
more info
 
identical protein binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 
heart morphogenesis IEA
Inferred from Electronic Annotation
more info
 
histone H3-K27 demethylation IEA
Inferred from Electronic Annotation
more info
 
histone H3-K4 methylation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
in utero embryonic development IEA
Inferred from Electronic Annotation
more info
 
mesodermal cell differentiation IEA
Inferred from Electronic Annotation
more info
 
multicellular organism growth IEA
Inferred from Electronic Annotation
more info
 
neural tube closure IEA
Inferred from Electronic Annotation
more info
 
notochord morphogenesis IEA
Inferred from Electronic Annotation
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 
respiratory system process IEA
Inferred from Electronic Annotation
more info
 
somite rostral/caudal axis specification IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
MLL3/4 complex IDA
Inferred from Direct Assay
more info
PubMed 
histone methyltransferase complex IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm TAS
Traceable Author Statement
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
lysine-specific demethylase 6A
Names
bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX))
histone demethylase UTX
lysine (K)-specific demethylase 6A
ubiquitously transcribed tetratricopeptide repeat protein X-linked
ubiquitously-transcribed TPR gene on the X chromosome

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_016260.1 RefSeqGene

    Range
    4999..244435
    Download
    GenBank, FASTA, Sequence Viewer (Graphics), LRG_616

mRNA and Protein(s)

  1. NM_001291415.1NP_001278344.1  lysine-specific demethylase 6A isoform 1

    See identical proteins and their annotated locations for NP_001278344.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AI364446, AL041377, AL831996, BC143277, BC143278, DC381812
    UniProtKB/TrEMBL
    B7ZKN5, B7ZKN6, Q86TD1
    Related
    ENSP00000483595, ENST00000611820
    Conserved Domains (6) summary
    pfam02373
    Location:11851293
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11511215
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:106399
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:130163
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:272303
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:285312
    TPR; TPR repeat [structural motif]
  2. NM_001291416.1NP_001278345.1  lysine-specific demethylase 6A isoform 2

    See identical proteins and their annotated locations for NP_001278345.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AI364446, AL041377, AL831996, BC143272, BC143278, DC381812
    UniProtKB/TrEMBL
    B7ZKN1, B7ZKN6, Q86TD1
    Related
    ENSP00000372355, ENST00000382899
    Conserved Domains (6) summary
    pfam02373
    Location:11401248
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11061170
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:106401
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:130163
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:272303
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:285312
    TPR; TPR repeat [structural motif]
  3. NM_001291417.1NP_001278346.1  lysine-specific demethylase 6A isoform 4

    See identical proteins and their annotated locations for NP_001278346.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) lacks two consecutive in-frame exons in the coding region, compared to variant 1. The resulting isoform (4) lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AI364446, AK303430, AL041377, AL831996, BC143278, DC381812
    UniProtKB/TrEMBL
    B4E0L8, B7ZKN6, Q86TD1
    Related
    ENSP00000437405, ENST00000536777
    Conserved Domains (7) summary
    pfam02373
    Location:10881196
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10541118
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    pfam00515
    Location:130163
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:128194
    TPR_11; TPR repeat
    pfam13424
    Location:205282
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:272303
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:285312
    TPR; TPR repeat [structural motif]
  4. NM_001291418.1NP_001278347.1  lysine-specific demethylase 6A isoform 5

    See identical proteins and their annotated locations for NP_001278347.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) lacks two consecutive in-frame exons and a single in-frame exon in the coding region, compared to variant 1. The resulting isoform (5) lacks two internal segments, compared to isoform 1.
    Source sequence(s)
    AB208795, AI364446, AL041377, BC143278, DC381812, DQ062677
    UniProtKB/TrEMBL
    B7ZKN6, E1U0S6, Q59HG3
    Conserved Domains (7) summary
    pfam02373
    Location:10541162
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10201084
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    pfam00515
    Location:130163
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:128194
    TPR_11; TPR repeat
    pfam13424
    Location:205282
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:272303
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:285312
    TPR; TPR repeat [structural motif]
  5. NM_001291421.1NP_001278350.1  lysine-specific demethylase 6A isoform 6

    See identical proteins and their annotated locations for NP_001278350.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) lacks an internal exon in the 5' region, which results in translation initiation from a downstream start codon, and also lacks two consecutive in-frame exons in the coding region, compared to variant 1. The resulting isoform (6) has a shorter N-terminus and lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AI364446, AL041377, AL831996, BC143275, BC143278, DC381812
    UniProtKB/TrEMBL
    B7ZKN6, Q86TD1
    Related
    ENSP00000405910, OTTHUMP00000023176, ENST00000414389, OTTHUMT00000056325
    Conserved Domains (6) summary
    pfam02373
    Location:837945
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:803867
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    pfam00515
    Location:67100
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:3197
    TPR_11; TPR repeat
    pfam13431
    Location:2152
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:3461
    TPR; TPR repeat [structural motif]
  6. NM_021140.3NP_066963.2  lysine-specific demethylase 6A isoform 3

    See identical proteins and their annotated locations for NP_066963.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks an in-frame exon in the coding region, compared to variant 1. The resulting isoform (3) lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AB208795, AI364446, AL041377, DC381812
    Consensus CDS
    CCDS14265.1
    UniProtKB/Swiss-Prot
    O15550
    UniProtKB/TrEMBL
    Q59HG3
    Related
    ENSP00000367203, OTTHUMP00000023175, ENST00000377967, OTTHUMT00000056324
    Conserved Domains (6) summary
    pfam02373
    Location:11331241
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10991163
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:106399
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:130163
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:272303
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:285312
    TPR; TPR repeat [structural motif]

RNA

  1. NR_111960.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) lacks two internal exons and has an alternate splice site in an internal exon,, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translation start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AB208795, AI364446, AK303430, AL041377, BC143272, DC381812, EU026291
    Related
    ENST00000543216

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p2 Primary Assembly

    Range
    44873175..45112779
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011543957.1XP_011542259.1  

    Conserved Domains (6) summary
    pfam02373
    Location:12041312
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11701234
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:145418
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:149182
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:291322
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:304331
    TPR; TPR repeat [structural motif]
  2. XM_011543960.1XP_011542262.1  

    Conserved Domains (6) summary
    pfam02373
    Location:12041312
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11701234
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:145418
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:149182
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:291322
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:304331
    TPR; TPR repeat [structural motif]
  3. XM_011543959.1XP_011542261.1  

    Conserved Domains (6) summary
    pfam02373
    Location:11701278
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11361200
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:145418
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:149182
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:291322
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:304331
    TPR; TPR repeat [structural motif]
  4. XM_011543962.1XP_011542264.1  

    Conserved Domains (6) summary
    pfam02373
    Location:11521260
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11181182
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:145418
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:149182
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:291322
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:304331
    TPR; TPR repeat [structural motif]
  5. XM_011543967.1XP_011542269.1  

    Conserved Domains (6) summary
    pfam02373
    Location:11521260
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11181182
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:145418
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:149182
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:291322
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:304331
    TPR; TPR repeat [structural motif]
  6. XM_011543966.1XP_011542268.1  

    Conserved Domains (6) summary
    pfam02373
    Location:11181226
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10841148
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:145418
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:149182
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:291322
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:304331
    TPR; TPR repeat [structural motif]
  7. XM_011543961.1XP_011542263.1  

    Conserved Domains (6) summary
    pfam02373
    Location:11591267
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11251189
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:145420
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:149182
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:291322
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:304331
    TPR; TPR repeat [structural motif]
  8. XM_011543965.1XP_011542267.1  

    Conserved Domains (6) summary
    pfam02373
    Location:11251233
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10911155
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:145420
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:149182
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:291322
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:304331
    TPR; TPR repeat [structural motif]
  9. XM_011543971.1XP_011542273.1  

    Conserved Domains (6) summary
    pfam02373
    Location:11251233
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10911155
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:145420
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:149182
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:291322
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:304331
    TPR; TPR repeat [structural motif]
  10. XM_011543968.1XP_011542270.1  

    Conserved Domains (7) summary
    pfam02373
    Location:11071215
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10731137
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    pfam00515
    Location:149182
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:148213
    TPR_11; TPR repeat
    pfam13424
    Location:224301
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:291322
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:304331
    TPR; TPR repeat [structural motif]
  11. XM_011543973.1XP_011542275.1  

    Conserved Domains (7) summary
    pfam02373
    Location:11071215
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10731137
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    pfam00515
    Location:149182
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:148213
    TPR_11; TPR repeat
    pfam13424
    Location:224301
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:291322
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:304331
    TPR; TPR repeat [structural motif]
  12. XM_011543958.1XP_011542260.1  

    Conserved Domains (6) summary
    pfam02373
    Location:11851293
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11511215
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:106399
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:130163
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:272303
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:285312
    TPR; TPR repeat [structural motif]
  13. XM_005272656.3XP_005272713.1  

    See identical proteins and their annotated locations for XP_005272713.1

    Conserved Domains (6) summary
    pfam02373
    Location:11511259
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11171181
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:106399
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:130163
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:272303
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:285312
    TPR; TPR repeat [structural motif]
  14. XM_011543964.1XP_011542266.1  

    Conserved Domains (6) summary
    pfam02373
    Location:11331241
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10991163
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:106399
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:130163
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:272303
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:285312
    TPR; TPR repeat [structural motif]
  15. XM_011543970.1XP_011542272.1  

    Conserved Domains (6) summary
    pfam02373
    Location:10991207
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10651129
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:106399
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:130163
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:272303
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:285312
    TPR; TPR repeat [structural motif]
  16. XM_005272659.3XP_005272716.1  

    See identical proteins and their annotated locations for XP_005272716.1

    Conserved Domains (6) summary
    pfam02373
    Location:10991207
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10651129
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:106399
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:130163
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:272303
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:285312
    TPR; TPR repeat [structural motif]
  17. XM_011543963.1XP_011542265.1  

    Conserved Domains (6) summary
    pfam02373
    Location:11401248
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11061170
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:106401
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:130163
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:272303
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:285312
    TPR; TPR repeat [structural motif]
  18. XM_011543969.1XP_011542271.1  

    Conserved Domains (6) summary
    pfam02373
    Location:11061214
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10721136
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:106401
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:130163
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:272303
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:285312
    TPR; TPR repeat [structural motif]
  19. XM_011543972.1XP_011542274.1  

    Conserved Domains (7) summary
    pfam02373
    Location:10881196
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10541118
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    pfam00515
    Location:130163
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:128194
    TPR_11; TPR repeat
    pfam13424
    Location:205282
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:272303
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:285312
    TPR; TPR repeat [structural motif]
  20. XM_011543974.1XP_011542276.1  

    Conserved Domains (6) summary
    pfam02373
    Location:11331241
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10991163
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:106399
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:130163
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:272303
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:285312
    TPR; TPR repeat [structural motif]
  21. XM_011543976.1XP_011542278.1  

    Conserved Domains (5) summary
    smart00558
    Location:11701215
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:145418
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam00515
    Location:149182
    TPR_1; Tetratricopeptide repeat
    pfam13431
    Location:291322
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:304331
    TPR; TPR repeat [structural motif]
  22. XM_011543975.1XP_011542277.1  

    Related
    ENSP00000398929, OTTHUMP00000023177, ENST00000433797, OTTHUMT00000056326
    Conserved Domains (6) summary
    pfam02373
    Location:9341042
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:900964
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    pfam00515
    Location:67100
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:3197
    TPR_11; TPR repeat
    pfam13431
    Location:2152
    TPR_17; Tetratricopeptide repeat
    sd00006
    Location:3461
    TPR; TPR repeat [structural motif]

RNA

  1. XR_949018.1 RNA Sequence

Alternate CHM1_1.1

Genomic

  1. NC_018934.2 Alternate CHM1_1.1

    Range
    44765275..45004750
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)