tpiA triosephosphate isomerase [Streptococcus pneumoniae ATCC 700669] - Gene

Summary

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Gene symbol: tpiA
Gene description: triosephosphate isomerase
Locus tag: SPN23F_15910
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Streptococcus pneumoniae ATCC 700669 (strain: ATCC 700669)
Lineage: Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus

Genomic context

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Sequence :: NC_011900.1 (1535392..1536150, complement)

NC_011900.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence

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Bibliography

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GeneRIFs: Gene References Into Functions What's a GeneRIF?

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Pathways from BioSystems

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Biosynthesis of amino acids, organism-specific biosystem (from KEGG)
Biosynthesis of amino acids, organism-specific biosystem
Biosynthesis of amino acids
Biosynthesis of amino acids, conserved biosystem (from KEGG)
Biosynthesis of amino acids, conserved biosystem
Biosynthesis of amino acids
Biosynthesis of secondary metabolites, organism-specific biosystem (from KEGG)
Biosynthesis of secondary metabolites, organism-specific biosystem
Biosynthesis of secondary metabolites
Fructose and mannose metabolism, organism-specific biosystem (from KEGG)
Fructose and mannose metabolism, organism-specific biosystem
Fructose and mannose metabolism
Fructose and mannose metabolism, conserved biosystem (from KEGG)
Fructose and mannose metabolism, conserved biosystem
Fructose and mannose metabolism
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate, organism-specific biosystem (from KEGG)
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate, organism-specific biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate, conserved biosystem (from KEGG)
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate, conserved biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Glycolysis / Gluconeogenesis, organism-specific biosystem (from KEGG)
Glycolysis / Gluconeogenesis, organism-specific biosystemGlycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabol...
Glycolysis / Gluconeogenesis, conserved biosystem (from KEGG)
Glycolysis / Gluconeogenesis, conserved biosystemGlycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabol...
Glycolysis, core module involving three-carbon compounds, organism-specific biosystem (from KEGG)
Glycolysis, core module involving three-carbon compounds, organism-specific biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Glycolysis, core module involving three-carbon compounds, conserved biosystem (from KEGG)
Glycolysis, core module involving three-carbon compounds, conserved biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Inositol phosphate metabolism, organism-specific biosystem (from KEGG)
Inositol phosphate metabolism, organism-specific biosystem
Inositol phosphate metabolism
Inositol phosphate metabolism, conserved biosystem (from KEGG)
Inositol phosphate metabolism, conserved biosystem
Inositol phosphate metabolism
Metabolic pathways, organism-specific biosystem (from KEGG)
Metabolic pathways, organism-specific biosystem
Metabolic pathways
Microbial metabolism in diverse environments, organism-specific biosystem (from KEGG)
Microbial metabolism in diverse environments, organism-specific biosystem
Microbial metabolism in diverse environments

General gene information

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Miscellaneous features

Loc: c1535655-1535623 inference = protein motif:ProSite:PS00171
Loc: c1536138-1535407 inference = protein motif:Pfam:PF00121

General protein information

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Names: triosephosphate isomerase

YP_002511488.1

EC 5.3.1.1

Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_011900.1

Range

1535392..1536150, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

YP_002511488.1 triosephosphate isomerase [Streptococcus pneumoniae ATCC 700669]

Status: PROVISIONAL

UniProtKB/TrEMBL

B8ZLT6

Conserved Domains (2) summary

PRK14567
Location:4 – 236
Blast Score: 446

PRK14567; triosephosphate isomerase; Provisional

cd00311
Location:5 – 236
Blast Score: 818

TIM; Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually ...