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    TYK2 tyrosine kinase 2 [ Homo sapiens ]

    Gene ID: 7297, updated on 19-May-2012
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    Summary

    Official Symbol
    TYK2provided by HGNC
    Official Full Name
    tyrosine kinase 2provided by HGNC
    Primary source
    HGNC:12440
    See related
    Ensembl:ENSG00000105397; HPRD:01490; MIM:176941; Vega:OTTHUMG00000166373
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    JTK1
    Summary
    This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]
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    Genomic context

    Location :
    19p13.2
    Sequence :
    Chromosome: 19; NC_000019.9 (10461204..10491248, complement)
    See TYK2 in Epigenomics, MapViewer

    Chromosome 19 - NC_000019.9Genomic Context describing neighboring genes Neighboring gene ribonucleoprotein, PTB-binding 1 Neighboring gene intercellular adhesion molecule 3 Neighboring gene cell division cycle 37 homolog (S. cerevisiae) Neighboring gene microRNA 1181 Neighboring gene phosphodiesterase 4A, cAMP-specific

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Non-receptor tyrosine kinase 2 reaches its lowest expression levels in human breast cancer during regional nodal metastasis. Sang QX, et al. Clin Exp Metastasis, 2012 Feb. PMID 22116632.
    2. Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus. Cunninghame Graham DS, et al. PLoS Genet, 2011 Oct. PMID 22046141.
    3. Human metapneumovirus inhibits IFN-β signaling by downregulating Jak1 and Tyk2 cellular levels. Ren J, et al. PLoS One, 2011. PMID 21949722.
    4. Systematic and quantitative assessment of the ubiquitin-modified proteome. Kim W, et al. Mol Cell, 2011 Oct 21. PMID 21906983.
    5. A directed protein interaction network for investigating intracellular signal transduction. Vinayagam A, et al. Sci Signal, 2011 Sep 6. PMID 21900206.

    See all (121) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. data highlight the role of TYK2 downregulation in breast cancer cell de-differentitation and initiation of regional metastasis
      Title: Non-receptor tyrosine kinase 2 reaches its lowest expression levels in human breast cancer during regional nodal metastasis.
    2. Association analysis identified five SLE susceptibility genes reaching genome-wide levels of significance : NCF2 ,IKZF1 ,IRF8 ,IFIH1 , and TYK2
      Title: Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus.
    3. infection of airway epithelial cells with hMPV decreased cellular level of Janus tyrosine kinase (Jak1) and tyrosine kinase 2 (Tyk2)
      Title: Human metapneumovirus inhibits IFN-β signaling by downregulating Jak1 and Tyk2 cellular levels.
    4. This meta-analysis demonstrates that autoimmune and inflammatory diseases is associated with TYK2 gene rs34536443 and rs2304256 polymorphisms, but not rs280523, rs280519, rs12720270 and rs12720356.
      Title: Meta-analysis of TYK2 gene polymorphisms association with susceptibility to autoimmune and inflammatory diseases.
    5. The consequent effect of SOCS1 inhibition of Tyk2 not only results in a reduced IFN response because of inhibition of Tyk2 kinase-mediated STAT signaling but also negatively impacts IFNAR1 surface expression, which is stabilized by Tyk2.
      Title: Suppressor of cytokine signaling (SOCS) 1 inhibits type I interferon (IFN) signaling via the interferon alpha receptor (IFNAR1)-associated tyrosine kinase Tyk2.
    6. Data suggest that TYK2 polymorphisms were not associated with systemic lupus erythematosus in Hong Kong Chinese, but that rs2304256 and rs12720270 may be associated with photosensitivity and discoid rash.
      Title: Lack of association of TYK2 gene polymorphisms in Chinese patients with systemic lupus erythematosus.
    7. The rs34536443 variant effect on multiple sclerosis susceptibility might be mediated by deviating T lymphocyte differentiation toward a Th2 phenotype.
      Title: Tyrosine kinase 2 variant influences T lymphocyte polarization and multiple sclerosis susceptibility.
    8. Tyk2 deficiency and clinical manifestations of hyper IgE syndromes (Review)
      Title: Clinical manifestations of hyper IgE syndromes.
    9. Siva-1 forms a functional complex with Tyk2 and participates in the transduction of signals that inhibit B lymphocyte growth.
      Title: Tyrosine kinase 2 interacts with the proapoptotic protein Siva-1 and augments its apoptotic functions.
    10. Meta-analysis of gene-disease association. (HuGE Navigator)
      Title: Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot".
    Submit: New GeneRIF Correction See all (42)
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    Phenotypes

    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

    Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.

    The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes.

    Tyrosine kinase 2 deficiency

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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    NP_003322.2 NP_006089.1 GNB2L1    BIND  PubMed RACK-1 interacts with Tyk2. 
    NP_003322.2 NP_997468.1 IFNAR2    BIND  PubMed IFNR-beta-L interacts with Tyk2. 
    NP_003322.2 IL12RB1    BIND  PubMed An unspecified isoform of IL12RB1 interacts with Tyk2. 
    NP_003322.2 NP_653321.1 JAKMIP1    BIND  PubMed Jamip1 interacts with Tyk2. 
    P29597 P22681 CBL    HPRD  PubMed  
    P29597 P46109 CRKL    HPRD  PubMed  
    P29597 P19525 EIF2AK2    HPRD  PubMed  
    P29597 P06241 FYN    HPRD  PubMed  
    P29597 P10912 GHR    HPRD  PubMed  
    P29597 P63244 GNB2L1    HPRD  PubMed  
    P29597 P48551 IFNAR2    HPRD  PubMed  
    P29597 P78552 IL13RA1    HPRD  PubMed  
    P29597 P40189 IL6ST    HPRD  PubMed  
    P29597 P35568 IRS1    HPRD  PubMed  
    P29597 Q9Y4H2 IRS2    HPRD  PubMed  
    P29597 P23458 JAK1    HPRD  PubMed  
    P29597 Janus kinase and microtubule interacting protein 1 JAKMIP1    HPRD  PubMed  
    P29597 P07948 LYN    HPRD  PubMed  
    P29597 P09619 PDGFRB    HPRD  PubMed  
    P29597 P27986 PIK3R1    HPRD  PubMed  
    P29597 Q03405 PLAUR    HPRD  PubMed  
    P29597 O14744 PRMT5    HPRD  PubMed  
    P29597 P25105 PTAFR    HPRD  PubMed  
    P29597 P18031 PTPN1    HPRD  PubMed  
    P29597 P29350 PTPN6    HPRD  PubMed  
    P29597 P08575 PTPRC    HPRD  PubMed  
    P29597 O75886 STAM2    HPRD  PubMed  
    P29597 P42224 STAT1    HPRD  PubMed  
    P29597 P52630 STAT2    HPRD  PubMed  
    P29597 P29597 TYK2    HPRD  PubMed  
    P29597 P15498 VAV1    HPRD  PubMed  
    P29597 P13010 XRCC5    HPRD  PubMed  
    BioGRID:113148 BioGRID:107315 CBL    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:113148 BioGRID:107789 CRKL    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:113148 BioGRID:108122 DNM2    BioGRID  PubMed Two-hybrid 
    BioGRID:113148 BioGRID:120541 ELP2    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:113148 BioGRID:108810 FYN    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:113148 BioGRID:108957 GHR    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:113148 BioGRID:115671 GNB2L1    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:113148 BioGRID:109676 IFNAR1    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:113148 BioGRID:109811 IL13RA1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:113148 BioGRID:109786 IL6ST    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:113148 BioGRID:114209 IRS2    BioGRID  PubMed Reconstituted Complex 
    BioGRID:113148 BioGRID:109919 JAK1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:113148 BioGRID:112927 KLF10    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:113148 BioGRID:110245 LYN    BioGRID  PubMed Reconstituted Complex 
    BioGRID:113148 BioGRID:111345 PLAUR    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:113148 BioGRID:115688 PRMT5    BioGRID  PubMed Reconstituted Complex 
    BioGRID:113148 BioGRID:111736 PTPN1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:113148 BioGRID:111742 PTPN6    BioGRID  PubMed Affinity Capture-Western; Biochemical Activity 
    BioGRID:113148 BioGRID:114203 SOCS1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:113148 BioGRID:115548 STAM2    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:113148 BioGRID:112649 STAT1    BioGRID  PubMed Biochemical Activity 
    BioGRID:113148 BioGRID:112938 TK1    BioGRID  PubMed Two-hybrid 
    BioGRID:113148 BioGRID:113148 TYK2    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:113148 BioGRID:113164 UBC    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:113148 BioGRID:113252 VAV1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:113148 BioGRID:113353 XRCC5    BioGRID  PubMed Affinity Capture-Western 
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    General gene information

    Markers

    Genotypes

    Homology

    Pathways from BioSystems

    • Cytokine Signaling in Immune system, organism-specific biosystem (from REACTOME)
      Cytokine Signaling in Immune system, organism-specific biosystemCytokines are small proteins that regulate and mediate immunity, inflammation, and hematopoiesis. They are secreted in response to immune stimuli, and usually act briefly, locally, at very low concen...
    • Epstein-Barr virus infection, organism-specific biosystem (from KEGG)
      Epstein-Barr virus infection, organism-specific biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
    • Epstein-Barr virus infection, conserved biosystem (from KEGG)
      Epstein-Barr virus infection, conserved biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
    • Hepatitis C, organism-specific biosystem (from KEGG)
      Hepatitis C, organism-specific biosystemHepatitis C virus (HCV) is a major cause of chronic liver disease. The HCV employ several strategies to perturb host cell immunity. After invasion, HCV RNA genome functions directly as an mRNA in the...
    • Hepatitis C, conserved biosystem (from KEGG)
      Hepatitis C, conserved biosystemHepatitis C virus (HCV) is a major cause of chronic liver disease. The HCV employ several strategies to perturb host cell immunity. After invasion, HCV RNA genome functions directly as an mRNA in the...
    • Herpes simplex infection, organism-specific biosystem (from KEGG)
      Herpes simplex infection, organism-specific biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
    • Herpes simplex infection, conserved biosystem (from KEGG)
      Herpes simplex infection, conserved biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
    • IL-3 Signaling Pathway, organism-specific biosystem (from WikiPathways)
      IL-3 Signaling Pathway, organism-specific biosystemInterleukin-3 belongs to a family of cytokines, which includes IL-5 and GM-CSF. It signals through a receptor complex comprising of an IL-3 specific IL-3 receptor alpha subunit (IL3RA) and a common b...
    • IL-4 signaling Pathway, organism-specific biosystem (from WikiPathways)
      IL-4 signaling Pathway, organism-specific biosystemInterleukin-4 belongs to the IL-2 family of cytokines, which includes IL-2, IL-7, IL-9, IL-15 and IL-21. It signals through 2 different receptor complexes; Receptor complex 1 comprises of IL-4 recept...
    • IL-6 Signaling Pathway, organism-specific biosystem (from WikiPathways)
      IL-6 Signaling Pathway, organism-specific biosystemInterleukin-6 belongs to a family of cytokines which includes IL-11, ciliary neurotrophic factor (CNTF), cardiotropin-1, cardiotrophin-like cytokine, leukemia inhibitory factor (LIF) and Oncostatin M...
    • IL-9 Signaling Pathway, organism-specific biosystem (from WikiPathways)
      IL-9 Signaling Pathway, organism-specific biosystemInterleukin-9 belongs to a family of cytokines, which includes IL-2, IL-4, IL-7, IL-15 and IL-21. It signals through a receptor complex consisting of an IL-9 receptor (IL9R) and a common gamma chain ...
    • IL12-mediated signaling events, organism-specific biosystem (from Pathway Interaction Database)
      IL12-mediated signaling events, organism-specific biosystem
      IL12-mediated signaling events
    • IL23-mediated signaling events, organism-specific biosystem (from Pathway Interaction Database)
      IL23-mediated signaling events, organism-specific biosystem
      IL23-mediated signaling events
    • IL27-mediated signaling events, organism-specific biosystem (from Pathway Interaction Database)
      IL27-mediated signaling events, organism-specific biosystem
      IL27-mediated signaling events
    • IL6-mediated signaling events, organism-specific biosystem (from Pathway Interaction Database)
      IL6-mediated signaling events, organism-specific biosystem
      IL6-mediated signaling events
    • Immune System, organism-specific biosystem (from REACTOME)
      Immune System, organism-specific biosystemHumans are exposed to millions of potential pathogens daily, through contact, ingestion, and inhalation. Our ability to avoid infection depends on the adaptive immune system and during the first crit...
    • Influenza A, organism-specific biosystem (from KEGG)
      Influenza A, organism-specific biosystemInfluenza is a contagious respiratory disease caused by influenza virus infection. Influenza A virus is responsible for both annual seasonal epidemics and periodic worldwide pandemics. Novel strains ...
    • Influenza A, conserved biosystem (from KEGG)
      Influenza A, conserved biosystemInfluenza is a contagious respiratory disease caused by influenza virus infection. Influenza A virus is responsible for both annual seasonal epidemics and periodic worldwide pandemics. Novel strains ...
    • Interferon Signaling, organism-specific biosystem (from REACTOME)
      Interferon Signaling, organism-specific biosystemInterferons (IFNs) are cytokines that play a central role in initiating immune responses, especially antiviral and antitumor effects. There are three types of IFNs:Type I (IFN-alpha, -beta and others...
    • Interferon alpha/beta signaling, organism-specific biosystem (from REACTOME)
      Interferon alpha/beta signaling, organism-specific biosystemType I interferons (IFNs) are composed of various genes including IFN alpha (IFNA), beta (IFNB), omega, epsilon, and kappa. In humans the IFNA genes are composed of more than 13 subfamily genes, wher...
    • Interleukin-6 signaling, organism-specific biosystem (from REACTOME)
      Interleukin-6 signaling, organism-specific biosystemInterleukin-6 (IL-6) is a pleiotropic cytokine with roles in processes including immune regulation, hematopoiesis, inflammation, oncogenesis, metabolic control and sleep. It is the founding member o...
    • Jak-STAT signaling pathway, organism-specific biosystem (from KEGG)
      Jak-STAT signaling pathway, organism-specific biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
    • Jak-STAT signaling pathway, conserved biosystem (from KEGG)
      Jak-STAT signaling pathway, conserved biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
    • Measles, organism-specific biosystem (from KEGG)
      Measles, organism-specific biosystemMeasles virus (MV) is highly contagious virus that leads infant death worldwide. Humans are the unique natural reservoir for this virus. It causes severe immunosuppression favouring secondary bacteri...
    • Measles, conserved biosystem (from KEGG)
      Measles, conserved biosystemMeasles virus (MV) is highly contagious virus that leads infant death worldwide. Humans are the unique natural reservoir for this virus. It causes severe immunosuppression favouring secondary bacteri...
    • Osteoclast differentiation, organism-specific biosystem (from KEGG)
      Osteoclast differentiation, organism-specific biosystemThe osteoclasts, multinucleared cells originating from the hematopoietic monocyte-macrophage lineage, are responsible for bone resorption. Osteoclastogenesis is mainly regulated by signaling pathways...
    • Osteoclast differentiation, conserved biosystem (from KEGG)
      Osteoclast differentiation, conserved biosystemThe osteoclasts, multinucleared cells originating from the hematopoietic monocyte-macrophage lineage, are responsible for bone resorption. Osteoclastogenesis is mainly regulated by signaling pathways...
    • Regulation of IFNA signaling, organism-specific biosystem (from REACTOME)
      Regulation of IFNA signaling, organism-specific biosystemThere are several proteins and mechanisms involved in controlling the extent of ligand stimulation of IFNA/B signaling. These mechanisms can effect every step of the IFNA/B cascade. Dephosphorylation...
    • Signaling by Interleukins, organism-specific biosystem (from REACTOME)
      Signaling by Interleukins, organism-specific biosystemInterleukins are low molecular weight proteins that bind to cell surface receptors and act in an autocrine and/or paracrine fashion. They were first identified as factors produced by leukocytes but a...
    • Signaling events mediated by PTP1B, organism-specific biosystem (from Pathway Interaction Database)
      Signaling events mediated by PTP1B, organism-specific biosystem
      Signaling events mediated by PTP1B
    • Toxoplasmosis, organism-specific biosystem (from KEGG)
      Toxoplasmosis, organism-specific biosystemToxoplasma gondii is an obligate intracellular parasite that is prevalent worldwide. The tachyzoite form acquired by oral ingestion downmodulates proinflammatory signaling pathways via various mechan...
    • Toxoplasmosis, conserved biosystem (from KEGG)
      Toxoplasmosis, conserved biosystemToxoplasma gondii is an obligate intracellular parasite that is prevalent worldwide. The tachyzoite form acquired by oral ingestion downmodulates proinflammatory signaling pathways via various mechan...

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    growth hormone receptor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    non-membrane spanning protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    protein tyrosine kinase activity TAS
    Traceable Author Statement
    more info
    		  
    Process Evidence Code Pubs
    cytokine-mediated signaling pathway TAS
    Traceable Author Statement
    more info
    		  
    intracellular protein kinase cascade IEA
    Inferred from Electronic Annotation
    more info
    		  
    protein phosphorylation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    regulation of type I interferon-mediated signaling pathway TAS
    Traceable Author Statement
    more info
    		  
    type I interferon-mediated signaling pathway TAS
    Traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    cytosol TAS
    Traceable Author Statement
    more info
    		  
    membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    non-receptor tyrosine-protein kinase TYK2
    Names
    non-receptor tyrosine-protein kinase TYK2
    NP_003322.3
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    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_007872.1 RefSeqGene

      Range
      5001..35045
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_003331.4 → NP_003322.3  non-receptor tyrosine-protein kinase TYK2

      Status: REVIEWED

      Source sequence(s)
      AK308360, BC014243, CR995139, DA864169
      Consensus CDS
      CCDS12236.1
      UniProtKB/Swiss-Prot
      P29597
      Related
      ENSP00000431885, OTTHUMP00000232746, ENST00000525621, OTTHUMT00000389443
      Conserved Domains (6) summary
      cd05076
      Location:593 – 867
      Blast Score: 1422
      PTK_Tyk2_rpt1; Pseudokinase (repeat 1) domain of the Protein Tyrosine Kinase, Tyrosine kinase 2
      cd05080
      Location:892 – 1174
      Blast Score: 1481
      PTKc_Tyk2_rpt2; Catalytic (repeat 2) domain of the Protein Tyrosine Kinase, Tyrosine kinase 2
      smart00219
      Location:897 – 1169
      Blast Score: 857
      TyrKc; Tyrosine kinase, catalytic domain
      smart00295
      Location:28 – 273
      Blast Score: 265
      B41; Band 4.1 homologues
      pfam07714
      Location:589 – 866
      Blast Score: 548
      Pkinase_Tyr; Protein tyrosine kinase
      cl15255
      Location:437 – 534
      Blast Score: 354
      SH2; Src homology 2 (SH2) domain

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000019.9 Reference GRCh37.p5 Primary Assembly

      Range
      10461204..10491248, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000151.1 Alternate HuRef

      Range
      10041213..10071290, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AC011557.7 (2997..32999) None
    genomic AY549314.1 AAS37680.1
    genomic CH471106.1 EAW84099.1
      EAW84100.1
    mRNA AK222672.1 BAD96392.1
    mRNA AK303627.1 BAG64635.1
    mRNA AK308360.1 None
    mRNA AK308379.1 None
    mRNA BC014243.2 AAH14243.1
    mRNA CR995139.1 None
    mRNA DA864169.1 None
    mRNA X54637.1 CAA38449.1
    other-genetic DQ892692.2 ABM83618.1
    other-genetic DQ895955.2 ABM86881.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    P29597.3 GenPept UniProtKB/Swiss-Prot:P29597
    Q53HA9 GenPept UniProtKB/TrEMBL:Q53HA9
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    Additional Links

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Medical
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

      Table of contents

      Links

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