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    TULP2 tubby like protein 2 [ Homo sapiens ]

    Gene ID: 7288, updated on 11-May-2012
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    Summary

    Official Symbol
    TULP2provided by HGNC
    Official Full Name
    tubby like protein 2provided by HGNC
    Primary source
    HGNC:12424
    See related
    Ensembl:ENSG00000104804; HPRD:03813; MIM:602309; Vega:OTTHUMG00000164406
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CT65; TUBL2
    Summary
    TULP2 is a member of a family of tubby-like genes (TULPs) that encode proteins of unknown function. Members of this family have been identified in plants, vertebrates, and invertebrates. The TULP proteins share a conserved C-terminal region of approximately 200 amino acid residues. [provided by RefSeq, Jul 2008]
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    Genomic context

    Location :
    19q13.1
    Sequence :
    Chromosome: 19; NC_000019.9 (49384222..49401996, complement)
    See TULP2 in Epigenomics, MapViewer

    Chromosome 19 - NC_000019.9Genomic Context describing neighboring genes Neighboring gene pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 Neighboring gene protein phosphatase 1, regulatory subunit 15A Neighboring gene nucleobindin 1 Neighboring gene dihydrodiol dehydrogenase (dimeric)

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514.
    2. Tubby proteins: the plot thickens. Carroll K, et al. Nat Rev Mol Cell Biol, 2004 Jan. PMID 14708010.
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
    4. Implication of tubby proteins as transcription factors by structure-based functional analysis. Boggon TJ, et al. Science, 1999 Dec 10. PMID 10591637.
    5. Molecular characterization of TUB, TULP1, and TULP2, members of the novel tubby gene family and their possible relation to ocular diseases. North MA, et al. Proc Natl Acad Sci U S A, 1997 Apr 1. PMID 9096357.

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Phenotypes

    Review eQTL and phenotype association data in this region using PheGenI

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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    O00295 Q01844 EWSR1    HPRD  PubMed  
    O00295 P50222 MEOX2    HPRD  PubMed  
    BioGRID:113139 BioGRID:108431 EWSR1    BioGRID  PubMed Two-hybrid 
    BioGRID:113139 BioGRID:110386 MEOX2    BioGRID  PubMed Two-hybrid 
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    General gene information

    Genotypes

    Homology

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    visual perception TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Preferred Names
    tubby-related protein 2
    Names
    tubby-related protein 2
    tubby-like protein 2
    cancer testis antigen 65
    cancer/testis antigen 65
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    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_003323.2 → NP_003314.2  tubby-related protein 2

      Status: VALIDATED

      Source sequence(s)
      AC026803, BC026070, DB442827, U82469
      Consensus CDS
      CCDS12739.1
      UniProtKB/Swiss-Prot
      O00295
      Related
      ENSP00000221399, OTTHUMP00000226636, ENST00000221399, OTTHUMT00000378633
      Conserved Domains (1) summary
      pfam01167
      Location:279 – 520
      Blast Score: 1117
      Tub; Tub family

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000019.9 Reference GRCh37.p5 Primary Assembly

      Range
      49384222..49401996, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000151.1 Alternate HuRef

      Range
      45760666..45778459, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AC026803.7 (118297..136013) None
    genomic CH471177.1 EAW52410.1
    mRNA BC026070.2 AAH26070.1
    mRNA DB442827.1 None
    mRNA U82469.1 AAB53701.1
    other-genetic DQ890936.2 ABM81862.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    O00295.2 GenPept UniProtKB/Swiss-Prot:O00295
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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