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Cul4b cullin 4B [ Mus musculus (house mouse) ]

Gene ID: 72584, updated on 8-May-2016
Official Symbol
Cul4bprovided by MGI
Official Full Name
cullin 4Bprovided by MGI
Primary source
MGI:MGI:1919834
See related
Ensembl:ENSMUSG00000031095
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CUL-4B; AA409770; mKIAA0695; 2700050M05Rik
Orthologs
Location:
X; X A2
Exon count:
23
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) X NC_000086.7 (38531616..38576196, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (35884793..35929373, complement)

Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 94 pseudogene Neighboring gene predicted gene 9488 Neighboring gene predicted gene, 34715 Neighboring gene malignant T cell amplified sequence 1 Neighboring gene C1GALT1-specific chaperone 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • KIAA0695

Gene Ontology Provided by MGI

Function Evidence Code Pubs
contributes_to damaged DNA binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
ubiquitin protein ligase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
DNA repair IEA
Inferred from Electronic Annotation
more info
 
UV-damage excision repair ISO
Inferred from Sequence Orthology
more info
 
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cellular response to DNA damage stimulus IBA
Inferred from Biological aspect of Ancestor
more info
 
histone H2A monoubiquitination ISO
Inferred from Sequence Orthology
more info
 
neuron projection development ISO
Inferred from Sequence Orthology
more info
 
positive regulation of G1/S transition of mitotic cell cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein ubiquitination involved in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Cul4B-RING E3 ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
Cul4B-RING E3 ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
 
cullin-RING ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
cullin-4B
Names
CUL-4B
cul4b

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001110142.1NP_001103612.1  cullin-4B

    See identical proteins and their annotated locations for NP_001103612.1

    Status: VALIDATED

    Source sequence(s)
    AI037712, AK032701, AK160998, AK164640, CJ072585
    Consensus CDS
    CCDS40948.1
    UniProtKB/Swiss-Prot
    A2A432
    UniProtKB/TrEMBL
    Q3TP81
    Related
    ENSMUSP00000059276, OTTMUSP00000049168, ENSMUST00000050083, OTTMUST00000089886
    Conserved Domains (3) summary
    smart00182
    Location:653793
    CULLIN; Cullin
    pfam00888
    Location:274872
    Cullin; Cullin family
    pfam10557
    Location:899964
    Cullin_Nedd8; Cullin protein neddylation domain
  2. NM_028288.5NP_082564.3  cullin-4B

    See identical proteins and their annotated locations for NP_082564.3

    Status: VALIDATED

    Source sequence(s)
    AI037712, AK032701, AK160998, AK164640
    Consensus CDS
    CCDS40948.1
    UniProtKB/Swiss-Prot
    A2A432
    UniProtKB/TrEMBL
    Q3TP81
    Related
    ENSMUSP00000110771, OTTMUSP00000018749, ENSMUST00000115118, OTTMUST00000041721
    Conserved Domains (3) summary
    smart00182
    Location:653793
    CULLIN; Cullin
    pfam00888
    Location:274872
    Cullin; Cullin family
    pfam10557
    Location:899964
    Cullin_Nedd8; Cullin protein neddylation domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000086.7 Reference GRCm38.p3 C57BL/6J

    Range
    38531616..38576196 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000042.1 Alternate Mm_Celera

    Range
    26177720..26222300 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)