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Ssbp3 single-stranded DNA binding protein 3 [ Mus musculus (house mouse) ]

Gene ID: 72475, updated on 8-May-2016
Official Symbol
Ssbp3provided by MGI
Official Full Name
single-stranded DNA binding protein 3provided by MGI
Primary source
MGI:MGI:1919725
See related
Ensembl:ENSMUSG00000061887 Vega:OTTMUSG00000008276
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
LAST; SSDP1; AI854733; AW551939; 2610021L12Rik; 2610200M23Rik; 5730488C10Rik
Summary
This gene encodes a member of the Ssdp (sequence-specific single-stranded DNA binding protein) family of proteins. The encoded protein binds specifically to single-stranded pyrimidine-rich DNA elements. The encoded protein has been shown to be important for head development and may play a role in the differentiation of spinal interneurons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Orthologs
Location:
4; 4 C7
Exon count:
20
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 4 NC_000070.6 (106911470..107049694)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (106584075..106722299)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 31065 Neighboring gene predicted gene, 31125 Neighboring gene predicted gene 12786 Neighboring gene mitochondrial ribosomal protein L37 Neighboring gene cytochrome b5 reductase-like Neighboring gene CUB domain containing protein 2

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
single-stranded DNA binding ISA
Inferred from Sequence Alignment
more info
PubMed 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 
protein complex IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
single-stranded DNA-binding protein 3
Names
Lck-associated signal transducer
sequence-specific single-stranded-DNA-binding protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023672.2NP_076161.2  single-stranded DNA-binding protein 3 isoform a

    See identical proteins and their annotated locations for NP_076161.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AI854733, AK011853, AK017711, CO429463, CX200383
    Consensus CDS
    CCDS18427.1
    UniProtKB/Swiss-Prot
    Q9D032
    Related
    ENSMUSP00000030367, OTTMUSP00000008624, ENSMUST00000030367, OTTMUST00000018799
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81367
    SSDP; Single-stranded DNA binding protein, SSDP
  2. NM_198438.1NP_940840.1  single-stranded DNA-binding protein 3 isoform b

    See identical proteins and their annotated locations for NP_940840.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. The encoded isoform (b) is shorter than isoform a.
    Source sequence(s)
    AI854733, AK011853, AK017711, AK153733, CO429463, CX200383
    Consensus CDS
    CCDS18428.1
    UniProtKB/Swiss-Prot
    Q9D032
    UniProtKB/TrEMBL
    Q3U5B9
    Related
    ENSMUSP00000072536, OTTMUSP00000008625, ENSMUST00000072753, OTTMUST00000018800
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81340
    SSDP; Single-stranded DNA binding protein, SSDP

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p3 C57BL/6J

    Range
    106911470..107049694
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006503411.1XP_006503474.1  

    See identical proteins and their annotated locations for XP_006503474.1

    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81389
    SSDP; Single-stranded DNA binding protein, SSDP
  2. XM_006503413.1XP_006503476.1  

    See identical proteins and their annotated locations for XP_006503476.1

    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81375
    SSDP; Single-stranded DNA binding protein, SSDP
  3. XM_006503412.1XP_006503475.1  

    See identical proteins and their annotated locations for XP_006503475.1

    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81381
    SSDP; Single-stranded DNA binding protein, SSDP
  4. XM_006503414.1XP_006503477.1  

    See identical proteins and their annotated locations for XP_006503477.1

    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81362
    SSDP; Single-stranded DNA binding protein, SSDP
  5. XM_006503416.1XP_006503479.1  

    See identical proteins and their annotated locations for XP_006503479.1

    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81348
    SSDP; Single-stranded DNA binding protein, SSDP
  6. XM_006503415.1XP_006503478.1  

    See identical proteins and their annotated locations for XP_006503478.1

    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81354
    SSDP; Single-stranded DNA binding protein, SSDP
  7. XM_006503417.2XP_006503480.1  

    Conserved Domains (1) summary
    pfam04503
    Location:1279
    SSDP; Single-stranded DNA binding protein, SSDP
  8. XM_006503420.1XP_006503483.1  

    Conserved Domains (1) summary
    pfam04503
    Location:12252
    SSDP; Single-stranded DNA binding protein, SSDP
  9. XM_006503419.1XP_006503482.1  

    See identical proteins and their annotated locations for XP_006503482.1

    Conserved Domains (1) summary
    pfam04503
    Location:1257
    SSDP; Single-stranded DNA binding protein, SSDP
  10. XM_006503418.2XP_006503481.1  

    See identical proteins and their annotated locations for XP_006503481.1

    UniProtKB/TrEMBL
    Q3U5B9
    Conserved Domains (1) summary
    pfam04503
    Location:31278
    SSDP; Single-stranded DNA binding protein, SSDP

Alternate Mm_Celera

Genomic

  1. AC_000026.1 Alternate Mm_Celera

    Range
    105272425..105410615
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)