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Plcd3 phospholipase C, delta 3 [ Mus musculus (house mouse) ]

Gene ID: 72469, updated on 8-May-2016
Official Symbol
Plcd3provided by MGI
Official Full Name
phospholipase C, delta 3provided by MGI
Primary source
MGI:MGI:107451
See related
Ensembl:ENSMUSG00000020937 Vega:OTTMUSG00000003295
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1964; 2610205J15Rik
Orthologs
Location:
11 E1; 11 66.71 cM
Exon count:
17
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 11 NC_000077.6 (103069236..103101658, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (102931610..102962972, complement)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene dephospho-CoA kinase domain containing Neighboring gene microRNA 6931 Neighboring gene N-myristoyltransferase 1 Neighboring gene predicted gene, 42090 Neighboring gene acyl-Coenzyme A binding domain containing 4 Neighboring gene hexamethylene bis-acetamide inducible 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 
phosphoric diester hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
angiogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 
labyrinthine layer blood vessel development IGI
Inferred from Genetic Interaction
more info
PubMed 
lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 
lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
regulation of cell proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3
Names
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3
PLC-delta-3
phosphoinositide phospholipase C-delta-3
phospholipase C-delta-3
NP_690026.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152813.3NP_690026.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

    See identical proteins and their annotated locations for NP_690026.2

    Status: VALIDATED

    Source sequence(s)
    AK011892, AK046669, AL731805, BY011789, BY589869
    Consensus CDS
    CCDS25512.1
    UniProtKB/Swiss-Prot
    Q8K2J0
    Related
    ENSMUSP00000099366, OTTMUSP00000003284, ENSMUST00000103077, OTTMUST00000006877
    Conserved Domains (6) summary
    pfam09279
    Location:251332
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    cd00275
    Location:656783
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08630
    Location:332627
    PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
    PLN02228
    Location:251778
    PLN02228; Phosphoinositide phospholipase C
    pfam14788
    Location:197246
    EF-hand_10; EF hand
    cd13363
    Location:61177
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p3 C57BL/6J

    Range
    103069236..103101658 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006534308.2XP_006534371.1  

    Conserved Domains (6) summary
    pfam09279
    Location:251332
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    cd00275
    Location:655782
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    PLN02228
    Location:251777
    PLN02228; Phosphoinositide phospholipase C
    pfam14788
    Location:197246
    EF-hand_10; EF hand
    cd13363
    Location:61177
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
    cl14615
    Location:332626
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
  2. XM_006534309.2XP_006534372.1  

    Conserved Domains (6) summary
    pfam09279
    Location:210291
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    cd00275
    Location:615742
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08630
    Location:291586
    PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
    PLN02228
    Location:210737
    PLN02228; Phosphoinositide phospholipase C
    pfam14788
    Location:156205
    EF-hand_10; EF hand
    cd13363
    Location:20136
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
  3. XM_006534310.2XP_006534373.1  

    Conserved Domains (6) summary
    pfam09279
    Location:191272
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    cd00275
    Location:596723
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08630
    Location:272567
    PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
    PLN02228
    Location:191718
    PLN02228; Phosphoinositide phospholipase C
    pfam14788
    Location:137186
    EF-hand_10; EF hand
    cd13363
    Location:1117
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain

Alternate Mm_Celera

Genomic

  1. AC_000033.1 Alternate Mm_Celera

    Range
    114788919..114811158 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)