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TRN-GTT2-7 tRNA-Asn (anticodon GTT) 2-7 [ Homo sapiens (human) ]

Gene ID: 7214, updated on 10-Oct-2023

Summary

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Official Symbol
TRN-GTT2-7provided by HGNC
Official Full Name
tRNA-Asn (anticodon GTT) 2-7provided by HGNC
Primary source
HGNC:HGNC:54714
See related
MIM:189880; AllianceGenome:HGNC:54714
Gene type
tRNA
RefSeq status
MODEL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TRN; TRN1
Summary
The saturation hybridization studies of Hatlen and Attardi (1971) [PubMed 4929578] indicated a copy number of tRNA genes of 1,300 for the haploid human genome--an average of 65 gene copies for each tRNA species. These genes tend to be clustered, an arrangement that would facilitate the exchange of sequence information and enable them to evolve together.[supplied by OMIM, Sep 2009]
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Genomic context

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Location:
1q21.1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (145287766..145287839)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (144412508..144412581)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (148248115..148248188)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase A like 4D Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr1:148241215-148241940 Neighboring gene uncharacterized LOC101060170 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1260 Neighboring gene RNA, variant U1 small nuclear 14 Neighboring gene NBPF member 20 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr1:148356511-148357172 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr1:148357173-148357832 Neighboring gene profilin 1 pseudogene 3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1608 Neighboring gene uncharacterized LOC105371288 Neighboring gene RNA, U1 small nuclear 154, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural comparison of human, bovine, rat, and Walker 256 carcinosarcoma asparaginyl-tRNA. Chen EY, et al. Biochim Biophys Acta, 1980 Dec 11. PMID 6783075
  2. Genomic organization of the human asparagine transfer RNA genes: localization to the U1 RNA gene and class I pseudogene repeat units. Buckland RA. Am J Hum Genet, 1989 Aug. PMID 2757033, Free PMC Article
  3. Proportion of HeLa cell genome complementary to transfer RNA and 5 s RNA. Hatlen L, et al. J Mol Biol, 1971 Mar 28. PMID 4929578
  4. Nup153 is an M9-containing mobile nucleoporin with a novel Ran-binding domain. Nakielny S, et al. EMBO J, 1999 Apr 1. PMID 10202161, Free PMC Article
  5. Functional conservation of the transportin nuclear import pathway in divergent organisms. Siomi MC, et al. Mol Cell Biol, 1998 Jul. PMID 9632798, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Other Names

  • tRNA asparagine 1 (anticodon GUU)
  • tRNA-Asn-GTT-2-7
  • transfer RNA asparagine 1 (anticodon GUU)
  • transfer RNA-Asn (GTT) 2-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    145287766..145287839
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    144412508..144412581
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
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