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Ercc8 excision repaiross-complementing rodent repair deficiency, complementation group 8 [ Mus musculus (house mouse) ]

Gene ID: 71991, updated on 8-May-2016
Official Symbol
Ercc8provided by MGI
Official Full Name
excision repaiross-complementing rodent repair deficiency, complementation group 8provided by MGI
Primary source
MGI:MGI:1919241
See related
Ensembl:ENSMUSG00000021694 Vega:OTTMUSG00000030543
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Csa; Ckn1; 2410022P04Rik; 2810431L23Rik; 4631412O06Rik; B130065P18Rik
Orthologs
Location:
13; 13 D
Exon count:
14
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 13 NC_000079.6 (108158694..108199284)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (108948932..108985175)

Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene small integral membrane protein 15 Neighboring gene NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2 Neighboring gene predicted gene, 32268 Neighboring gene ELOVL family member 7, elongation of long chain fatty acids (yeast) Neighboring gene predicted gene, 32376 Neighboring gene predicted gene, 30747

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein complex binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to ubiquitin-protein transferase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
DNA repair IEA
Inferred from Electronic Annotation
more info
 
cellular response to DNA damage stimulus ISO
Inferred from Sequence Orthology
more info
 
nucleotide-excision repair ISO
Inferred from Sequence Orthology
more info
 
positive regulation of DNA repair ISO
Inferred from Sequence Orthology
more info
 
proteasome-mediated ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
protein autoubiquitination ISO
Inferred from Sequence Orthology
more info
 
protein polyubiquitination ISO
Inferred from Sequence Orthology
more info
 
response to UV IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to UV ISO
Inferred from Sequence Orthology
more info
 
response to X-ray IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to oxidative stress ISO
Inferred from Sequence Orthology
more info
 
transcription-coupled nucleotide-excision repair ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
Cul4A-RING E3 ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
 
nuclear matrix ISO
Inferred from Sequence Orthology
more info
 
nucleotide-excision repair complex ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
protein complex ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
DNA excision repair protein ERCC-8
Names
Cockayne syndrome 1 homolog
cockayne syndrome WD repeat protein CSA homolog

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028042.3NP_082318.2  DNA excision repair protein ERCC-8

    See identical proteins and their annotated locations for NP_082318.2

    Status: PROVISIONAL

    Source sequence(s)
    AK157175
    Consensus CDS
    CCDS26761.1
    UniProtKB/Swiss-Prot
    Q8CFD5
    Related
    ENSMUSP00000059211, OTTMUSP00000039667, ENSMUST00000054835, OTTMUST00000075602
    Conserved Domains (2) summary
    COG2319
    Location:40369
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:40361
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000079.6 Reference GRCm38.p3 C57BL/6J

    Range
    108158694..108199284
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011244697.1XP_011242999.1  

    Conserved Domains (2) summary
    COG2319
    Location:42201
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:40201
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. XM_006517763.2XP_006517826.1  

    See identical proteins and their annotated locations for XP_006517826.1

    UniProtKB/TrEMBL
    Q3TZV2
    Conserved Domains (2) summary
    COG2319
    Location:4248
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:4248
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RNA

  1. XR_382743.2 RNA Sequence

  2. XR_382744.2 RNA Sequence

Alternate Mm_Celera

Genomic

  1. AC_000035.1 Alternate Mm_Celera

    Range
    112496203..112532195
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)