Csl citrate synthase like [Mus musculus (house mouse)] - Gene

Summary

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Official Symbol: Cslprovided by MGI
Official Full Name: citrate synthase likeprovided by MGI
Primary source: MGI:1919082
See related: Ensembl:ENSMUSG00000046934
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 1700007H16Rik

Genomic context

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Location :: 10 D1; 10

Sequence :: Chromosome: 10; NC_000076.6 (99757705..99759658, complement)

See Csl in Epigenomics, MapViewer

Chromosome 10 - NC_000076.6 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

Bibliography

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GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from BioSystems

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2-Oxocarboxylic acid metabolism, organism-specific biosystem (from KEGG)
2-Oxocarboxylic acid metabolism, organism-specific biosystem2-Oxocarboxylic acids are the most elementary set of metabolites that includes pyruvate (2-oxopropanoate), 2-oxobutanoate, oxaloacetate (2-oxobutanedioate) and 2-oxoglutarate. This diagram illustrate...
2-Oxocarboxylic acid metabolism, conserved biosystem (from KEGG)
2-Oxocarboxylic acid metabolism, conserved biosystem2-Oxocarboxylic acids are the most elementary set of metabolites that includes pyruvate (2-oxopropanoate), 2-oxobutanoate, oxaloacetate (2-oxobutanedioate) and 2-oxoglutarate. This diagram illustrate...
Biosynthesis of amino acids, organism-specific biosystem (from KEGG)
Biosynthesis of amino acids, organism-specific biosystem
Biosynthesis of amino acids
Biosynthesis of amino acids, conserved biosystem (from KEGG)
Biosynthesis of amino acids, conserved biosystem
Biosynthesis of amino acids
Citrate cycle (TCA cycle), organism-specific biosystem (from KEGG)
Citrate cycle (TCA cycle), organism-specific biosystemThe citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form ...
Citrate cycle (TCA cycle), conserved biosystem (from KEGG)
Citrate cycle (TCA cycle), conserved biosystemThe citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form ...
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate, organism-specific biosystem (from KEGG)
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate, organism-specific biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate, conserved biosystem (from KEGG)
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate, conserved biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Citric acid cycle (TCA cycle), organism-specific biosystem (from REACTOME)
Citric acid cycle (TCA cycle), organism-specific biosystemcomputationally inferred pathway (not manually curated)
Glyoxylate and dicarboxylate metabolism, organism-specific biosystem (from KEGG)
Glyoxylate and dicarboxylate metabolism, organism-specific biosystem
Glyoxylate and dicarboxylate metabolism
Glyoxylate and dicarboxylate metabolism, conserved biosystem (from KEGG)
Glyoxylate and dicarboxylate metabolism, conserved biosystem
Glyoxylate and dicarboxylate metabolism
Metabolism, organism-specific biosystem (from REACTOME)
Metabolism, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Pyruvate metabolism and Citric Acid (TCA) cycle, organism-specific biosystem (from REACTOME)
Pyruvate metabolism and Citric Acid (TCA) cycle, organism-specific biosystemcomputationally inferred pathway (not manually curated)
The citric acid (TCA) cycle and respiratory electron transport, organism-specific biosystem (from REACTOME)
The citric acid (TCA) cycle and respiratory electron transport, organism-specific biosystemcomputationally inferred pathway (not manually curated)

General gene information

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Markers

WI-12459 (e-PCR)
- UniSTS:28220

05.MMHAP6FRB8.seq (e-PCR)
- UniSTS:186290

Homology

Homologs of the Csl gene: The Csl gene is conserved in S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, and A.thaliana.
OrthoDB: The Hierarchical Catalog of Eukaryotic Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
molecular_function	ND No biological Data available more info
transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
biological_process	ND No biological Data available more info
metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
mitochondrion	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: citrate synthase-like protein

Names: citrate synthase-like protein

NP_082221.2

EC 2.3.3.1

EC 4.1.3.7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_027945.3 → NP_082221.2 citrate synthase-like protein

Status: VALIDATED

Source sequence(s)

AC158633, AK005713, AK161295

Consensus CDS

CCDS24149.1

UniProtKB/TrEMBL

Q80X68

UniProtKB/TrEMBL

Q9DAM4

Related

ENSMUSP00000052373, ENSMUST00000056085

Conserved Domains (2) summary

cd06105
Location:33 – 459
Blast Score: 2359

ScCit1-2_like; Saccharomyces cerevisiae (Sc) citrate synthases Cit1-2_like. Citrate synthases (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) with oxaloacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or ...

TIGR01793
Location:30 – 457
Blast Score: 1943

cit_synth_euk; citrate (Si)-synthase, eukaryotic

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 103

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p1 C57BL/6J

Genomic

NC_000076.6 Reference GRCm38.p1 C57BL/6J

Range

99757705..99759658, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

AC_000032.1 Alternate Mm_Celera

Range

101725527..101727480, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Nucleotide		Protein	Strain
Heading	Accession and Version	Protein	Strain
genomic	AAHY01088129.1 (1887..3840)	None
genomic	AC158633.7 (15112..17065)	None
genomic	CH466539.1	EDL21651.1	mixed
mRNA	AK005713.1	BAB24200.1	C57BL/6J
mRNA	AK161295.1	BAE36302.1	C57BL/6J
mRNA	BC050750.1	AAH50750.1