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SMG7 SMG7 nonsense mediated mRNA decay factor [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 717603, updated on 5-Mar-2024

Summary

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Official Symbol
SMG7provided by VGNC
Official Full Name
SMG7 nonsense mediated mRNA decay factorprovided by VGNC
Primary source
VGNC:VGNC:77725
See related
Ensembl:ENSMMUG00000018458
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
27
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (40732922..40821135)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (183748000..183836915, complement)

Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene laminin subunit gamma 2 Neighboring gene nicotinamide nucleotide adenylyltransferase 2 Neighboring gene uncharacterized LOC114679499 Neighboring gene neutrophil cytosolic factor 2 Neighboring gene actin related protein 2/3 complex subunit 5 Neighboring gene ral guanine nucleotide dissociation stimulator like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables telomerase RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables telomeric DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of telomerase holoenzyme complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein SMG7
Names
smg-7 homolog, nonsense mediated mRNA decay factor
XP_002802068.3
XP_002802069.3
XP_014977546.2
XP_014977550.2
XP_014977558.2
XP_014977569.1
XP_014977598.1
XP_014977612.1
XP_014977630.1
XP_028707133.1
XP_028707134.1
XP_028707137.1
XP_028707141.1
XP_028707147.1
XP_028707153.1
XP_028707157.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041754.1 Reference Mmul_10 Primary Assembly

    Range
    40732922..40821135
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002802022.3 → XP_002802068.3  protein SMG7 isoform X1

    UniProtKB/TrEMBL
    F7C550
    Conserved Domains (3) summary
    sd00006
    Location:460 → 486
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:477 → 737
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:361 → 473
    EST1; Telomerase activating protein Est1

  2. XM_002802023.3 → XP_002802069.3  protein SMG7 isoform X3

    UniProtKB/TrEMBL
    F7C550
    Conserved Domains (3) summary
    sd00006
    Location:460 → 486
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:477 → 737
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:361 → 473
    EST1; Telomerase activating protein Est1

  3. XM_015122064.2 → XP_014977550.2  protein SMG7 isoform X4

    UniProtKB/TrEMBL
    F7C550
    Conserved Domains (3) summary
    sd00006
    Location:460 → 486
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:477 → 737
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:361 → 473
    EST1; Telomerase activating protein Est1

  4. XM_015122072.2 → XP_014977558.2  protein SMG7 isoform X5

    UniProtKB/TrEMBL
    F7C550
    Conserved Domains (3) summary
    sd00006
    Location:460 → 486
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:477 → 737
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:361 → 473
    EST1; Telomerase activating protein Est1

  5. XM_015122060.2 → XP_014977546.2  protein SMG7 isoform X2

    UniProtKB/TrEMBL
    F7C550, F7C572
    Related
    ENSMMUP00000037894.3, ENSMMUT00000044871.3
    Conserved Domains (3) summary
    sd00006
    Location:460 → 486
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:477 → 737
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:361 → 473
    EST1; Telomerase activating protein Est1

  6. XM_015122083.2 → XP_014977569.1  protein SMG7 isoform X6

    UniProtKB/TrEMBL
    H9EU06
    Conserved Domains (3) summary
    sd00006
    Location:154 → 180
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:171 → 431
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:55 → 167
    EST1; Telomerase activating protein Est1

  7. XM_015122112.2 → XP_014977598.1  protein SMG7 isoform X7

    UniProtKB/TrEMBL
    H9EU06
    Conserved Domains (3) summary
    sd00006
    Location:183 → 209
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:200 → 460
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:84 → 196
    EST1; Telomerase activating protein Est1

  8. XM_028851304.1 → XP_028707137.1  protein SMG7 isoform X8

    UniProtKB/TrEMBL
    H9ETW8
    Conserved Domains (3) summary
    sd00006
    Location:183 → 209
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:200 → 460
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:84 → 196
    EST1; Telomerase activating protein Est1

  9. XM_028851320.1 → XP_028707153.1  protein SMG7 isoform X10

    UniProtKB/TrEMBL
    A0A5F7ZL77, H9ETW8
    Related
    ENSMMUP00000066389.1, ENSMMUT00000108693.1
    Conserved Domains (3) summary
    sd00006
    Location:183 → 209
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:200 → 460
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:84 → 196
    EST1; Telomerase activating protein Est1

  10. XM_028851324.1 → XP_028707157.1  protein SMG7 isoform X11

    Conserved Domains (1) summary
    pfam10373
    Location:1 → 96
    EST1_DNA_bind; Est1 DNA/RNA binding domain

  11. XM_015122144.2 → XP_014977630.1  protein SMG7 isoform X8

    UniProtKB/TrEMBL
    H9ETW8
    Conserved Domains (3) summary
    sd00006
    Location:183 → 209
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:200 → 460
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:84 → 196
    EST1; Telomerase activating protein Est1

  12. XM_028851314.1 → XP_028707147.1  protein SMG7 isoform X9

    UniProtKB/TrEMBL
    H9EU06
    Related
    ENSMMUP00000065880.1, ENSMMUT00000088511.1
    Conserved Domains (3) summary
    sd00006
    Location:136 → 162
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:153 → 413
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:37 → 149
    EST1; Telomerase activating protein Est1

  13. XM_015122126.2 → XP_014977612.1  protein SMG7 isoform X7

    UniProtKB/TrEMBL
    H9EU06
    Conserved Domains (3) summary
    sd00006
    Location:183 → 209
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:200 → 460
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:84 → 196
    EST1; Telomerase activating protein Est1

  14. XM_028851300.1 → XP_028707133.1  protein SMG7 isoform X7

    UniProtKB/TrEMBL
    H9EU06
    Conserved Domains (3) summary
    sd00006
    Location:183 → 209
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:200 → 460
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:84 → 196
    EST1; Telomerase activating protein Est1

  15. XM_028851308.1 → XP_028707141.1  protein SMG7 isoform X9

    UniProtKB/TrEMBL
    H9EU06
    Related
    ENSMMUP00000060627.2, ENSMMUT00000076466.2
    Conserved Domains (3) summary
    sd00006
    Location:136 → 162
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:153 → 413
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:37 → 149
    EST1; Telomerase activating protein Est1

  16. XM_028851301.1 → XP_028707134.1  protein SMG7 isoform X7

    UniProtKB/TrEMBL
    H9EU06
    Conserved Domains (3) summary
    sd00006
    Location:183 → 209
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:200 → 460
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:84 → 196
    EST1; Telomerase activating protein Est1
Nucleotide Protein
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