PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: PCK2provided by VGNC
Official Full Name: phosphoenolpyruvate carboxykinase 2, mitochondrialprovided by VGNC
Primary source: VGNC:VGNC:75780
See related: Ensembl:ENSMMUG00000021590
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	7	NC_041760.1 (86177977..86188002)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	7	NC_027899.1 (85502110..85511976)

Chromosome 7 - NC_041760.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

SHGC-34002 (e-PCR)
- UniSTS:65102

G27394 (e-PCR)
- UniSTS:20675

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables manganese ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables phosphoenolpyruvate carboxykinase (GTP) activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cellular response to dexamethasone stimulus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to glucose stimulus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to insulin stimulus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in gluconeogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in glycerol biosynthetic process from pyruvate	IEA Inferred from Electronic Annotation more info	PubMed
involved_in hepatocyte differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in propionate catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to starvation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: phosphoenolpyruvate carboxykinase [GTP], mitochondrial

NP_001252866.1

EC 4.1.1.32

EC 4.1.1.49

XP_014998830.1

EC 4.1.1.32

EC 4.1.1.49

XP_028706327.1

EC 4.1.1.32

EC 4.1.1.49

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001265937.2 → NP_001252866.1 phosphoenolpyruvate carboxykinase [GTP], mitochondrial

See identical proteins and their annotated locations for NP_001252866.1

Status: PROVISIONAL

Source sequence(s)

JV635486

UniProtKB/TrEMBL

F7E8L2, F7E8L8

Related

ENSMMUP00000028436.2, ENSMMUT00000030386.4

Conserved Domains (1) summary

cd00819
Location:44 → 633

PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041760.1 Reference Mmul_10 Primary Assembly

Range

86177977..86188002

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_028850494.1 → XP_028706327.1 phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X1

Conserved Domains (1) summary

cd00819
Location:1 → 499

PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...
XM_015143344.2 → XP_014998830.1 phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X1

Conserved Domains (1) summary

cd00819
Location:1 → 499

PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...