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    GSK3B glycogen synthase kinase 3 beta [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713114, updated on 18-May-2013
    Gene symbol
    GSK3B
    Gene description
    glycogen synthase kinase 3 beta
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Location :
    chromosome: 2
    Sequence :
    Chromosome: 2; NC_007859.1 (39860211..40127836, complement)
    See GSK3B in MapViewer

    Chromosome 2 - NC_007859.1Genomic Context describing neighboring genes Neighboring gene MYCBP/AMY-1-associated, testis expressed 1 Neighboring gene nuclear receptor subfamily 1, group I, member 2 Neighboring gene presenilins-associated rhomboid-like protein, mitochondrial-like Neighboring gene G protein-coupled receptor 156 Neighboring gene prostate tumor-overexpressed gene 1 protein-like

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

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    • Alzheimer's disease, conserved biosystem (from KEGG)
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    • Axon guidance, organism-specific biosystem (from KEGG)
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    • Axon guidance, conserved biosystem (from KEGG)
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    • B cell receptor signaling pathway, organism-specific biosystem (from KEGG)
      B cell receptor signaling pathway, organism-specific biosystemB cells are an important component of adaptive immunity. They produce and secrete millions of different antibody molecules, each of which recognizes a different (foreign) antigen. The B cell receptor...
    • B cell receptor signaling pathway, conserved biosystem (from KEGG)
      B cell receptor signaling pathway, conserved biosystemB cells are an important component of adaptive immunity. They produce and secrete millions of different antibody molecules, each of which recognizes a different (foreign) antigen. The B cell receptor...
    • Basal cell carcinoma, organism-specific biosystem (from KEGG)
      Basal cell carcinoma, organism-specific biosystemCancer of the skin is the most common cancer in Caucasians and basal cell carcinomas (BCC) account for 90% of all skin cancers. The vast majority of BCC cases are sporadic, though there is a rare fam...
    • Basal cell carcinoma, conserved biosystem (from KEGG)
      Basal cell carcinoma, conserved biosystemCancer of the skin is the most common cancer in Caucasians and basal cell carcinomas (BCC) account for 90% of all skin cancers. The vast majority of BCC cases are sporadic, though there is a rare fam...
    • Cell cycle, organism-specific biosystem (from KEGG)
      Cell cycle, organism-specific biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps known as G1 and G2 phases. Cycli...
    • Cell cycle, conserved biosystem (from KEGG)
      Cell cycle, conserved biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps known as G1 and G2 phases. Cycli...
    • Chemokine signaling pathway, organism-specific biosystem (from KEGG)
      Chemokine signaling pathway, organism-specific biosystemInflammatory immune response requires the recruitment of leukocytes to the site of inflammation upon foreign insult. Chemokines are small chemoattractant peptides that provide directional cues for th...
    • Chemokine signaling pathway, conserved biosystem (from KEGG)
      Chemokine signaling pathway, conserved biosystemInflammatory immune response requires the recruitment of leukocytes to the site of inflammation upon foreign insult. Chemokines are small chemoattractant peptides that provide directional cues for th...
    • Colorectal cancer, organism-specific biosystem (from KEGG)
      Colorectal cancer, organism-specific biosystemColorectal cancer (CRC) is the second largest cause of cancer-related deaths in Western countries. CRC arises from the colorectal epithelium as a result of the accumulation of genetic alterations in ...
    • Colorectal cancer, conserved biosystem (from KEGG)
      Colorectal cancer, conserved biosystemColorectal cancer (CRC) is the second largest cause of cancer-related deaths in Western countries. CRC arises from the colorectal epithelium as a result of the accumulation of genetic alterations in ...
    • Dopaminergic synapse, organism-specific biosystem (from KEGG)
      Dopaminergic synapse, organism-specific biosystemDopamine (DA) is an important and prototypical slow neurotransmitter in the mammalian brain, where it controls a variety of functions including locomotor activity, motivation and reward, learning an...
    • Dopaminergic synapse, conserved biosystem (from KEGG)
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    • Endometrial cancer, organism-specific biosystem (from KEGG)
      Endometrial cancer, organism-specific biosystemEndometrial cancer (EC) is the most common gynaecological malignancy and the fourth most common malignancy in women in the developed world after breast, colorectal and lung cancer. Two types of endom...
    • Endometrial cancer, conserved biosystem (from KEGG)
      Endometrial cancer, conserved biosystemEndometrial cancer (EC) is the most common gynaecological malignancy and the fourth most common malignancy in women in the developed world after breast, colorectal and lung cancer. Two types of endom...
    • Epstein-Barr virus infection, organism-specific biosystem (from KEGG)
      Epstein-Barr virus infection, organism-specific biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
    • Epstein-Barr virus infection, conserved biosystem (from KEGG)
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    • ErbB signaling pathway, organism-specific biosystem (from KEGG)
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    • ErbB signaling pathway, conserved biosystem (from KEGG)
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    • HTLV-I infection, organism-specific biosystem (from KEGG)
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    • HTLV-I infection, conserved biosystem (from KEGG)
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    • Hepatitis C, organism-specific biosystem (from KEGG)
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    • Hepatitis C, conserved biosystem (from KEGG)
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    • Neurotrophin signaling pathway, conserved biosystem (from KEGG)
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      Pathways in cancer, organism-specific biosystem
      Pathways in cancer
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    • T cell receptor signaling pathway, conserved biosystem (from KEGG)
      T cell receptor signaling pathway, conserved biosystemActivation of T lymphocytes is a key event for an efficient response of the immune system. It requires the involvement of the T-cell receptor (TCR) as well as costimulatory molecules such as CD28. En...
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    • Wnt signaling pathway, conserved biosystem (from KEGG)
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    Markers

    Homology

    Preferred Names
    glycogen synthase kinase-3 beta
    Names
    glycogen synthase kinase 3 beta

    RefSeqs of Annotated Genomes: Build 1.2

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly (based on Mmul_051212)

    Genomic

    1. NC_007859.1

      Range
      39860211..40127836, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001110431.2XP_001110431.2  

      Conserved Domains (2) summary
      pfam00069
      Location:56353
      Blast Score: 652
      Pkinase; Protein kinase domain
      cl09925
      Location:56360
      Blast Score: 675
      PKc_like; Protein Kinases, catalytic domain
    2. XM_001110505.2XP_001110505.1  

      Conserved Domains (2) summary
      pfam00069
      Location:56340
      Blast Score: 664
      Pkinase; Protein kinase domain
      cl09925
      Location:56347
      Blast Score: 696
      PKc_like; Protein Kinases, catalytic domain

      Supplemental Content

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