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MAP3K4 mitogen-activated protein kinase kinase kinase 4 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 710360, updated on 5-Mar-2024

Summary

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Official Symbol
MAP3K4provided by VGNC
Official Full Name
mitogen-activated protein kinase kinase kinase 4provided by VGNC
Primary source
VGNC:VGNC:81463
See related
Ensembl:ENSMMUG00000006143
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See MAP3K4 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
28
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (9624101..9751423, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (162052133..162180071)

Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene parkin RBR E3 ubiquitin protein ligase Neighboring gene uncharacterized LOC106998112 Neighboring gene uncharacterized LOC114677451 Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 4 Neighboring gene uncharacterized LOC100428594 Neighboring gene plasminogen

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of stress-activated MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mitogen-activated protein kinase kinase kinase 4
XP_014993127.2
XP_014993128.2
XP_014993129.2
XP_014993130.2
XP_014993131.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041757.1 Reference Mmul_10 Primary Assembly

    Range
    9624101..9751423 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015137644.2 → XP_014993130.2  mitogen-activated protein kinase kinase kinase 4 isoform X4

    UniProtKB/TrEMBL
    G7MR07
    Related
    ENSMMUP00000078265.1, ENSMMUT00000095124.1
    Conserved Domains (1) summary
    cd06626
    Location:1288 → 1547
    STKc_MEKK4; Catalytic domain of the Protein Serine/Threonine Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 4

  2. XM_015137642.2 → XP_014993128.2  mitogen-activated protein kinase kinase kinase 4 isoform X2

    UniProtKB/TrEMBL
    G7MR07
    Related
    ENSMMUP00000068800.1, ENSMMUT00000104043.1
    Conserved Domains (1) summary
    cd06626
    Location:1334 → 1593
    STKc_MEKK4; Catalytic domain of the Protein Serine/Threonine Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 4

  3. XM_015137643.2 → XP_014993129.2  mitogen-activated protein kinase kinase kinase 4 isoform X3

    UniProtKB/TrEMBL
    G7MR07
    Related
    ENSMMUP00000057287.2, ENSMMUT00000063499.2
    Conserved Domains (1) summary
    cd06626
    Location:1292 → 1551
    STKc_MEKK4; Catalytic domain of the Protein Serine/Threonine Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 4

  4. XM_015137641.2 → XP_014993127.2  mitogen-activated protein kinase kinase kinase 4 isoform X1

    UniProtKB/TrEMBL
    G7MR07
    Conserved Domains (1) summary
    cd06626
    Location:1338 → 1597
    STKc_MEKK4; Catalytic domain of the Protein Serine/Threonine Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 4

  5. XM_015137645.2 → XP_014993131.2  mitogen-activated protein kinase kinase kinase 4 isoform X5

    UniProtKB/TrEMBL
    A0A1D5Q359
    Related
    ENSMMUP00000042471.2, ENSMMUT00000073473.2
    Conserved Domains (1) summary
    cl21453
    Location:1338 → 1411
    PKc_like; Protein Kinases, catalytic domain

RNA

  1. XR_001444566.2 RNA Sequence

Nucleotide Protein
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