Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information

THY1 Thy-1 cell surface antigen [ Homo sapiens (human) ]

Gene ID: 7070, updated on 12-Apr-2014
Official Symbol
THY1provided by HGNC
Official Full Name
Thy-1 cell surface antigenprovided by HGNC
Primary source
HGNC:11801
See related
HPRD:01769; HPRD:11283; MIM:188230
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CD90
Location :
11q23.3
Sequence :
Chromosome: 11; NC_000011.10 (119417945..119423536, complement)
See THY1 in Epigenomics, MapViewer

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 2 Neighboring gene USP2 antisense RNA 1 (head to head) Neighboring gene hippocampus abundant transcript-like 1 pseudogene Neighboring gene double homeobox A pseudogene 5 Neighboring gene keratin 8 pseudogene 7

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Protein interactions

Protein Gene Interaction Pubs
Gag, Pr55 gag HIV Gag proteins adopt a ring-like supramolecular organization at sites of intercellular contacts and co-localize with CD63 tetraspanin and raft components GM1, Thy-1, and CD59 PubMed
gag The Matrix protein of HIV-1 Gag co-localizes with Thy-1 in lipid rafts, the site of virus particle budding from cells, and Thy-1 is incorporated into virus particles as a result of this process PubMed
matrix gag HIV-1 Matrix co-localizes with Thy-1 in lipid rafts, the site of virus particle budding from cells, and Thy-1 is incorporated into virus particles as a result of this process PubMed

Go to the HIV-1, Human Protein Interaction Database

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
GPI anchor binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Rho GTPase activator activity ISS
Inferred from Sequence or Structural Similarity
more info
 
integrin binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
T cell receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
angiogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
cell-cell adhesion ISS
Inferred from Sequence or Structural Similarity
more info
 
cytoskeleton organization ISS
Inferred from Sequence or Structural Similarity
more info
 
focal adhesion assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of T cell receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of axonogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of cell migration ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of protein kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of GTPase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of T cell activation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of release of sequestered calcium ion into cytosol ISS
Inferred from Sequence or Structural Similarity
more info
 
retinal cone cell development ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
anchored component of external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 
apical plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IEA
Inferred from Electronic Annotation
more info
 
dendrite IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 
external side of plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
extracellular vesicular exosome IDA
Inferred from Direct Assay
more info
PubMed 
growth cone ISS
Inferred from Sequence or Structural Similarity
more info
 
integral component of plasma membrane TAS
Traceable Author Statement
more info
PubMed 
membrane raft NAS
Non-traceable Author Statement
more info
PubMed 
plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
thy-1 membrane glycoprotein
Names
thy-1 membrane glycoprotein
CDw90
thy-1 antigen
Thy-1 T-cell antigen

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_006288.3NP_006279.2  thy-1 membrane glycoprotein preproprotein

    See proteins identical to NP_006279.2

    Status: VALIDATED

    Source sequence(s)
    AK090996, AP003396, BM504140
    Consensus CDS
    CCDS8424.1
    UniProtKB/TrEMBL
    B0YJA4
    UniProtKB/Swiss-Prot
    P04216
    Conserved Domains (2) summary
    smart00410
    Location:32122
    Blast Score: 82
    IG_like; Immunoglobulin like
    pfam00047
    Location:32104
    Blast Score: 94
    ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38 Primary Assembly

    Range
    119417945..119423536, complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

  1. AC_000143.1 Alternate HuRef

    Range
    115230310..115235710, complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018922.2 Alternate CHM1_1.1

    Range
    119175213..119180804, complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...