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APH1B aph-1 homolog B, gamma-secretase subunit [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 705718, updated on 5-Mar-2024

Summary

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Official Symbol
APH1Bprovided by VGNC
Official Full Name
aph-1 homolog B, gamma-secretase subunitprovided by VGNC
Primary source
VGNC:VGNC:69891
See related
Ensembl:ENSMMUG00000059755
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
7
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (39722355..39751415)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (39862143..39891226)

Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S27 like Neighboring gene RAB8B, member RAS oncogene family Neighboring gene uncharacterized LOC114679424 Neighboring gene carbonic anhydrase 12 Neighboring gene ubiquitin specific peptidase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein-macromolecule adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch receptor processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of catalytic activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of gamma-secretase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
gamma-secretase subunit APH-1B
Names
anterior pharynx defective 1 homolog B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041760.1 Reference Mmul_10 Primary Assembly

    Range
    39722355..39751415
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001105067.4 → XP_001105067.2  gamma-secretase subunit APH-1B isoform X1

    UniProtKB/TrEMBL
    F7DK04, G7MXS4, H9G0E6
    Related
    ENSMMUP00000075184.1, ENSMMUT00000087122.1
    Conserved Domains (1) summary
    pfam06105
    Location:3 → 232
    Aph-1; Aph-1 protein

  2. XM_028851016.1 → XP_028706849.1  gamma-secretase subunit APH-1B isoform X2

    Conserved Domains (1) summary
    pfam06105
    Location:3 → 186
    Aph-1; Aph-1 protein
Nucleotide Protein
Heading Accession and Version

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