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TOPORS TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 703930, updated on 5-Mar-2024

Summary

Official Symbol
TOPORSprovided by VGNC
Official Full Name
TOP1 binding arginine/serine rich protein, E3 ubiquitin ligaseprovided by VGNC
Primary source
VGNC:VGNC:79330
See related
Ensembl:ENSMMUG00000002686
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
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Genomic context

Location:
chromosome: 15
Exon count:
3
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (51334949..51346827)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (51401019..51412645)

Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene TATA-box binding protein associated factor 1 like Neighboring gene DNA fragmentation factor subunit beta pseudogene Neighboring gene NADH:ubiquinone oxidoreductase subunit B6 Neighboring gene small integral membrane protein 27 Neighboring gene RNA sensor RIG-I Neighboring gene aconitase 1

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in protein monoubiquitination IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein polyubiquitination IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
E3 ubiquitin-protein ligase Topors
NP_001253070.1
XP_028690114.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266141.1NP_001253070.1  E3 ubiquitin-protein ligase Topors

    See identical proteins and their annotated locations for NP_001253070.1

    Status: PROVISIONAL

    Source sequence(s)
    JU473914
    UniProtKB/TrEMBL
    A0A1D5R1G3, F7HPZ6
    Related
    ENSMMUP00000054147.1, ENSMMUT00000060549.2
    Conserved Domains (1) summary
    cd00162
    Location:102145
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041768.1 Reference Mmul_10 Primary Assembly

    Range
    51334949..51346827
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028834281.1XP_028690114.1  E3 ubiquitin-protein ligase Topors isoform X1

    UniProtKB/TrEMBL
    F7HPZ6
    Conserved Domains (1) summary
    cd16574
    Location:3877
    RING-HC_Topors; RING finger, HC subclass, found in topoisomerase I-binding arginine/serine-rich protein (Topors) and similar proteins