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Fam135b family with sequence similarity 135, member B [ Mus musculus (house mouse) ]

Gene ID: 70363, updated on 5-Mar-2024

Summary

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Official Symbol
Fam135bprovided by MGI
Official Full Name
family with sequence similarity 135, member Bprovided by MGI
Primary source
MGI:MGI:1917613
See related
Ensembl:ENSMUSG00000036800 AllianceGenome:MGI:1917613
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700010C24Rik; A830008O07Rik
Summary
Predicted to be involved in cellular lipid metabolic process. Is expressed in medulla oblongata; spinal cord; and ventral grey horn. Orthologous to human FAM135B (family with sequence similarity 135 member B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cerebellum adult (RPKM 2.5), cortex adult (RPKM 2.0) and 5 other tissues See more
Orthologs
human all
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Genomic context

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Location:
15 D3; 15 32.19 cM
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (71310800..71600282, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (71438951..71728434, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene FCF1 small subunit processome component homolog pseudogene Neighboring gene prune homolog pseudogene Neighboring gene STARR-seq mESC enhancer starr_38922 Neighboring gene STARR-positive B cell enhancer mm9_chr15:71568232-71568532 Neighboring gene STARR-seq mESC enhancer starr_38923 Neighboring gene predicted gene, 22519 Neighboring gene eukaryotic translation initiation factor 4A2 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Markers

Homology

Clone Names

  • MGC159348, MGC159350

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in cellular lipid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
protein FAM135B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177819.3 → NP_808487.2  protein FAM135B

    See identical proteins and their annotated locations for NP_808487.2

    Status: VALIDATED

    Source sequence(s)
    AC125528, AC157277, AC157602, AK005816, BC119174
    Consensus CDS
    CCDS49626.1
    UniProtKB/Swiss-Prot
    Q9DAI6
    Related
    ENSMUSP00000022953.9, ENSMUST00000022953.10
    Conserved Domains (2) summary
    pfam05057
    Location:1133 → 1327
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111 → 170
    DUF3657; Protein FAM135

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    71310800..71600282 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006521393.4 → XP_006521456.1  protein FAM135B isoform X1

    See identical proteins and their annotated locations for XP_006521456.1

    UniProtKB/Swiss-Prot
    Q9DAI6
    Conserved Domains (2) summary
    pfam05057
    Location:1133 → 1327
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111 → 170
    DUF3657; Protein FAM135

  2. XM_006521395.4 → XP_006521458.1  protein FAM135B isoform X1

    See identical proteins and their annotated locations for XP_006521458.1

    UniProtKB/Swiss-Prot
    Q9DAI6
    Conserved Domains (2) summary
    pfam05057
    Location:1133 → 1327
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111 → 170
    DUF3657; Protein FAM135

RNA

  1. XR_003951438.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9DAI6.3 GenPept UniProtKB/Swiss-Prot:Q9DAI6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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