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    BUB1B budding uninhibited by benzimidazoles 1 homolog beta (yeast) [ Homo sapiens ]

    Gene ID: 701, updated on 19-May-2012
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    Summary

    Official Symbol
    BUB1Bprovided by HGNC
    Official Full Name
    budding uninhibited by benzimidazoles 1 homolog beta (yeast)provided by HGNC
    Primary source
    HGNC:1149
    See related
    Ensembl:ENSG00000156970; HPRD:04176; MIM:602860; Vega:OTTHUMG00000129877
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    SSK1; BUBR1; Bub1A; MAD3L; hBUBR1; BUB1beta
    Summary
    This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008]
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    Genomic context

    Location :
    15q15
    Sequence :
    Chromosome: 15; NC_000015.9 (40453210..40513337)
    See BUB1B in Epigenomics, MapViewer

    Chromosome 15 - NC_000015.9Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100131089 Neighboring gene Bcl2 modifying factor Neighboring gene p21 protein (Cdc42/Rac)-activated kinase 6 Neighboring gene chromosome 15 open reading frame 56 Neighboring gene ankyrin repeat domain 63

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner. Lara-Gonzalez P, et al. J Cell Sci, 2011 Dec 15. PMID 22193957.
    2. BubR1 is modified by sumoylation during mitotic progression. Yang F, et al. J Biol Chem, 2012 Feb 10. PMID 22167194.
    3. Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes. Altun M, et al. Chem Biol, 2011 Nov 23. PMID 22118674.
    4. Combined expression of BUB1B, DLGAP5, and PINK1 as predictors of poor outcome in adrenocortical tumors: validation in a Brazilian cohort of adult and pediatric patients. Fragoso MC, et al. Eur J Endocrinol, 2012 Jan. PMID 22048964.
    5. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Bolanos-Garcia VM, et al. Structure, 2011 Nov 9. PMID 22000412.

    See all (107) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. a new type of post-translational modification that is essential for BubR1 function during mitosis.
      Title: BubR1 is modified by sumoylation during mitotic progression.
    2. we identify the Blinkin motif critical for interaction with BUBR1, define the stoichiometry and affinity of the interaction, and present a 2.2 Angstrom resolution crystal structure of the complex
      Title: Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site.
    3. DLGAP5-PINK1 and BUB1B-PINK1 were strong predictors of disease-free survival and overall survival, respectively, among adult patients with ACT.
      Title: Combined expression of BUB1B, DLGAP5, and PINK1 as predictors of poor outcome in adrenocortical tumors: validation in a Brazilian cohort of adult and pediatric patients.
    4. Aging-related loss of BubR1 and subsequent impairment of reactivity to reactive oxygen species may explain reduced proliferative capacity of aged smooth muscle cells.
      Title: Reduced proliferation of aged human vascular smooth muscle cells--role of oxygen-derived free radicals and BubR1 expression.
    5. Our data imply the possibility that BUBR1 may be involved in the progression of oral squamous cell carcinoma, and suggest that BUBR1 may be a promising prognostic marker in patients with OSCC
      Title: BUBR1 expression in oral squamous cell carcinoma and its relationship to tumor stage and survival.
    6. BUBR1 and closed MAD2 (C-MAD2) interact directly to assemble a functional mitotic checkpoint complex
      Title: BUBR1 and closed MAD2 (C-MAD2) interact directly to assemble a functional mitotic checkpoint complex.
    7. Targeting of CENP-E and BubR1 to the kinetochores and the interaction between CENP-E and BubR1 are significantly reduced in EpoB-resistant A549 cell line, compared to A549 cells.
      Title: The interaction between mitotic checkpoint proteins, CENP-E and BubR1, is diminished in epothilone B-resistant A549 cells.
    8. BUBR1 is required for ubiquitin-mediated proteasomal degradation of cell division cycle protein 20 in the G0 phase and maintains anaphase-promoting complex/cyclosome-CDC20 homolog 1 activity that regulates the optimal level of dishevelled for ciliogenesis
      Title: Insufficiency of BUBR1, a mitotic spindle checkpoint regulator, causes impaired ciliogenesis in vertebrates.
    9. this study suggests that evaluation of BUBR1, MAD2 and Aurora A expression levels is likely to improve accuracy of prognostic predictions in invasive ductal breast carcinoma
      Title: Expression of cell-cycle regulatory proteins BUBR1, MAD2, Aurora A, cyclin A and cyclin E in invasive ductal breast carcinomas.
    10. h-KNL1 functions to connect Bub1 and BubR1 with the hMis12, Ndc80, and Zwint-1 complexes.
      Title: Protein interaction domain mapping of human kinetochore protein Blinkin reveals a consensus motif for binding of spindle assembly checkpoint proteins Bub1 and BubR1.
    Submit: New GeneRIF Correction See all (56)
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    Phenotypes

    Review eQTL and phenotype association data in this region using PheGenI

    Colorectal cancer

    Mosaic variegated aneuploidy syndrome

    Premature chromatid separation trait

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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    NP_001202.3 NP_001246.1 CDC20    BIND  PubMed BubR1 interacts with Cdc20. 
    O60566 Q9UJX3 ANAPC7    HPRD  PubMed  
    O60566 Q10567 AP1B1    HPRD  PubMed  
    O60566 P63010 AP2B1    HPRD  PubMed  
    O60566 O00203 AP3B1    HPRD  PubMed  
    O60566 Q9Y6B7 AP4B1    HPRD  PubMed  
    O60566 P51587 BRCA2    HPRD  PubMed  
    O60566 O43684 BUB3    HPRD  PubMed  
    O60566 Q13042 CDC16    HPRD  PubMed  
    O60566 Q12834 CDC20    HPRD  PubMed  
    O60566 P30260 CDC27    HPRD  PubMed  
    O60566 Q02224 CENPE    HPRD  PubMed  
    O60566 Q13547 HDAC1    HPRD  PubMed  
    O60566 Q9Y6R4 MAP3K4    HPRD  PubMed  
    O60566 O76070 SNCG    HPRD  PubMed  
    BioGRID:107166 BioGRID:118937 ANAPC2    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:107166 BioGRID:118982 ANAPC4    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:107166 BioGRID:119538 ANAPC7    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:107166 BioGRID:106672 AP2B1    BioGRID  PubMed Reconstituted Complex; Two-hybrid 
    BioGRID:107166 BioGRID:106821 APC    BioGRID  PubMed Biochemical Activity 
    BioGRID:107166 BioGRID:201352 Anapc1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:107166 BioGRID:206755 Anapc16    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:107166 BioGRID:221196 Anapc2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:107166 BioGRID:208479 Anapc5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:107166 BioGRID:107142 BRCA2    BioGRID  PubMed Reconstituted Complex; Two-hybrid 
    BioGRID:107166 BioGRID:107164 BUB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:107166 BioGRID:107166 BUB1B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:107166 BioGRID:114621 BUB3    BioGRID  PubMed Affinity Capture-Western; Co-purification; Two-hybrid 
    BioGRID:107166 BioGRID:198404 Bub1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:107166 BioGRID:198405 Bub1b    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:107166 BioGRID:121354 CASC5    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:107166 BioGRID:114400 CDC16    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:107166 BioGRID:107427 CDC20    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Co-purification; Reconstituted Complex; Two-hybrid 
    BioGRID:107166 BioGRID:107431 CDC27    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:107166 BioGRID:107491 CENPE    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:107166 BioGRID:213776 Cdc16    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:107166 BioGRID:223749 Cdc20    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:107166 BioGRID:206665 Cdc23    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:107166 BioGRID:580243 Gm9174    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:107166 BioGRID:109315 HDAC1    BioGRID  PubMed Affinity Capture-Western; Co-purification 
    BioGRID:107166 BioGRID:114375 KAT2B    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:107166 BioGRID:110260 MAD2L1    BioGRID  PubMed Affinity Capture-Western; Co-purification 
    BioGRID:107166 BioGRID:122474 MIS12    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:107166 BioGRID:207818 Mad2l1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:107166 BioGRID:211970 Mis12    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:107166 BioGRID:117433 NSL1    BioGRID  PubMed Co-localization 
    BioGRID:107166 BioGRID:211904 Ndc80    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:107166 BioGRID:106652 PARP1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:107166 BioGRID:112507 SNCG    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex; Two-hybrid 
    BioGRID:107166 BioGRID:113164 UBC    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:107166 BioGRID:116249 UBE2C    BioGRID  PubMed Co-fractionation 
    BioGRID:107166 BioGRID:116303 ZWINT    BioGRID  PubMed Affinity Capture-MS 
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    General gene information

    Markers

    Genotypes

    Homology

    Pathways from BioSystems

    • APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem (from REACTOME)
      APC/C-mediated degradation of cell cycle proteins, organism-specific biosystemThe Anaphase Promoting Complex or Cyclosome (APC/C) functions during mitosis to promote sister chromatid separation and mitotic exit through the degradation of mitotic cyclins and securin. This compl...
    • APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem (from REACTOME)
      APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystemFollowing phosphorylation of the APC/C core subunits by mitotic kinases, the activating protein, Cdc20 is recruited to the APC and promotes the multiubiquitination and subsequent degradation of the ...
    • Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem (from REACTOME)
      Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystemAPC/C:Cdc20 is first activated at the prometaphase/metaphase transition through phosphorylation of core subunits of the APC/C by mitotic kinases as well as recruitment of the APC/C activator protein ...
    • Cell Cycle, organism-specific biosystem (from REACTOME)
      Cell Cycle, organism-specific biosystem
      Cell Cycle
    • Cell Cycle Checkpoints, organism-specific biosystem (from REACTOME)
      Cell Cycle Checkpoints, organism-specific biosystemA hallmark of the human cell cycle in normal somatic cells is its precision. This remarkable fidelity is achieved by a number of signal transduction pathways, known as checkpoints, which monitor cell...
    • Cell Cycle, Mitotic, organism-specific biosystem (from REACTOME)
      Cell Cycle, Mitotic, organism-specific biosystemThe replication of the genome and the subsequent segregation of chromosomes into daughter cells are controlled by a series of events collectively known as the cell cycle. DNA replication is carried o...
    • Cell cycle, organism-specific biosystem (from WikiPathways)
      Cell cycle, organism-specific biosystem(From http://en.wikipedia.org/wiki/Cell_cycle) The cell cycle is the series of events that takes place in a cell leading to its division and duplication (replication). Regulation of the cell cycle in...
    • Cell cycle, organism-specific biosystem (from KEGG)
      Cell cycle, organism-specific biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps known as G1 and G2 phases. Cycli...
    • Cell cycle, conserved biosystem (from KEGG)
      Cell cycle, conserved biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps known as G1 and G2 phases. Cycli...
    • DNA Replication, organism-specific biosystem (from REACTOME)
      DNA Replication, organism-specific biosystemStudies in the past decade have suggested that the basic mechanism of DNA replication initiation is conserved in all kingdoms of life. Initiation in unicellular eukaryotes, in particular Saccharomyce...
    • HTLV-I infection, organism-specific biosystem (from KEGG)
      HTLV-I infection, organism-specific biosystemHuman T-lymphotropic virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammato...
    • HTLV-I infection, conserved biosystem (from KEGG)
      HTLV-I infection, conserved biosystemHuman T-lymphotropic virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammato...
    • Inactivation of APC/C via direct inhibition of the APC/C complex, organism-specific biosystem (from REACTOME)
      Inactivation of APC/C via direct inhibition of the APC/C complex, organism-specific biosystemIn the direct inhibition model, the cytosolic Mitotic Checkpoint Complex, consisting of hBUBR1, hBUB3, Cdc20 and Mad2, directly inhibits APC/C by binding to it.
    • Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components, organism-specific biosystem (from REACTOME)
      Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components, organism-specific biosystemThe target of the mitotic checkpoint is the Anaphase Promoting Complex/Cyclosome (APC/C) an E3 ubiquitin ligase that targets proteins whose destruction is essential for mitotic exit. Currently, there...
    • M Phase, organism-specific biosystem (from REACTOME)
      M Phase, organism-specific biosystemMitosis, or the M phase, involves nuclear division and cytokinesis, where two identical daughter cells are produced. Mitosis involves prophase, prometaphase, metaphase, anaphase, and telophase. Fin...
    • Mitotic M-M/G1 phases, organism-specific biosystem (from REACTOME)
      Mitotic M-M/G1 phases, organism-specific biosystem
      Mitotic M-M/G1 phases
    • Mitotic Prometaphase, organism-specific biosystem (from REACTOME)
      Mitotic Prometaphase, organism-specific biosystemThe dissolution of the nuclear membrane marks the beginning of the prometaphase. Kinetochores are created when proteins attach to the centromeres. Microtubules then attach at the kinetochores, and ...
    • Mitotic Spindle Checkpoint, organism-specific biosystem (from REACTOME)
      Mitotic Spindle Checkpoint, organism-specific biosystemThe mitotic checkpoint or spindle assembly checkpoint is an evolutionarily conserved mechanism that ensures that cells with misaligned chromosomes do not exit mitosis and divide to form aneuploid cel...
    • PLK1 signaling events, organism-specific biosystem (from Pathway Interaction Database)
      PLK1 signaling events, organism-specific biosystem
      PLK1 signaling events
    • Regulation of APC/C activators between G1/S and early anaphase, organism-specific biosystem (from REACTOME)
      Regulation of APC/C activators between G1/S and early anaphase, organism-specific biosystemThe APC/C is activated by either Cdc20 or Cdh1. While both activators associate with the APC/C, they do so at different points in the cell cycle and their binding is regulated differently (see Zacha...
    • Regulation of mitotic cell cycle, organism-specific biosystem (from REACTOME)
      Regulation of mitotic cell cycle, organism-specific biosystem
      Regulation of mitotic cell cycle

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    protein kinase activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    M phase of mitotic cell cycle TAS
    Traceable Author Statement
    more info
    		  
    anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process TAS
    Traceable Author Statement
    more info
    		  
    apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    cell cycle NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    cell cycle checkpoint TAS
    Traceable Author Statement
    more info
    		  
    cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    cell proliferation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    mitosis NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    mitotic cell cycle TAS
    Traceable Author Statement
    more info
    		  
    mitotic cell cycle checkpoint TAS
    Traceable Author Statement
    more info
    		 PubMed 
    mitotic cell cycle spindle assembly checkpoint TAS
    Traceable Author Statement
    more info
    		  
    mitotic metaphase/anaphase transition IEA
    Inferred from Electronic Annotation
    more info
    		  
    mitotic prometaphase TAS
    Traceable Author Statement
    more info
    		  
    negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS
    Traceable Author Statement
    more info
    		  
    phosphatidylinositol-mediated signaling NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    protein localization to kinetochore IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    protein phosphorylation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    protein phosphorylation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS
    Traceable Author Statement
    more info
    		  
    spindle organization NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    anaphase-promoting complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    condensed chromosome kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    condensed chromosome outer kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    cytosol TAS
    Traceable Author Statement
    more info
    		  
    kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    colocalizes_with kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    colocalizes_with kinetochore NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    colocalizes_with kinetochore TAS
    Traceable Author Statement
    more info
    		 PubMed 
    microtubule organizing center IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    spindle midzone NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    mitotic checkpoint serine/threonine-protein kinase BUB1 beta
    Names
    mitotic checkpoint serine/threonine-protein kinase BUB1 beta
    mitotic checkpoint kinase MAD3L
    MAD3/BUB1-related protein kinase
    NP_001202.4
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    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_016338.1 RefSeqGene

      Range
      5001..65128
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001211.5 → NP_001202.4  mitotic checkpoint serine/threonine-protein kinase BUB1 beta

      Status: REVIEWED

      Source sequence(s)
      AC025429, AF053306, AI742619
      Consensus CDS
      CCDS10053.1
      UniProtKB/Swiss-Prot
      O60566
      Related
      ENSP00000287598, OTTHUMP00000160319, ENST00000287598, OTTHUMT00000252122
      Conserved Domains (3) summary
      COG0515
      Location:825 – 1015
      Blast Score: 88
      SPS1; Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]
      cl07066
      Location:57 – 179
      Blast Score: 487
      Mad3_BUB1_I; Mad3/BUB1 homology region 1
      cl09925
      Location:837 – 920
      Blast Score: 111
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000015.9 Reference GRCh37.p5 Primary Assembly

      Range
      40453210..40513337
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000147.1 Alternate HuRef

      Range
      17296260..17356314
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Help top of page

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AC025429.6 (79548..139674) None
    genomic AF310214.1 AAL10712.1
    genomic AF441125.1 None
    genomic CH471125.1 EAW92394.1
    mRNA AB208782.1 BAD92019.1
    mRNA AF035933.1 AAC23736.1
    mRNA AF046079.2 AAC12730.2
    mRNA AF046918.1 AAC33435.1
    mRNA AF053306.1 AAC06260.1
    mRNA AF068760.1 AAC19118.1
    mRNA AF107297.1 AAD11941.1
    mRNA AI742619.1 None
    mRNA AK296795.1 BAG59371.1
    mRNA AK296984.1 BAG59525.1
    mRNA AK312709.1 BAG35587.1
    mRNA AL597325.1 None
    mRNA BC018739.1 AAH18739.1
    other-genetic JF432304.1 ADZ15521.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    O60566.3 GenPept UniProtKB/Swiss-Prot:O60566
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Medical
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

      Table of contents

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