FOXO3 forkhead box O3 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: FOXO3provided by VGNC
Official Full Name: forkhead box O3provided by VGNC
Primary source: VGNC:VGNC:72704
See related: Ensembl:ENSMMUG00000020369
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 4

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	4	NC_041757.1 (12240576..12366665)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	4	NC_027896.1 (159244149..159371395, complement)

Chromosome 4 - NC_041757.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

FOXO1, 3, and 4 as well as their upstream regulator, AKT/p-AKT, was examined in rhesus macaque ovaries of three developmental stages: fetal, prepubertal, and adult
Title: Characterization of FOXO1, 3 and 4 transcription factors in ovaries of fetal, prepubertal and adult rhesus macaques.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

A008N03 (e-PCR)
- UniSTS:42785

RH75343 (e-PCR)
- UniSTS:85845

SHGC-36190 (e-PCR)
- UniSTS:59989

MARC_14315-14316:1007670343:1 (e-PCR)
- UniSTS:267641

RH78823 (e-PCR)
- UniSTS:89240

Foxo3 (e-PCR), detects polymorphism
- UniSTS:547229

D17S1454E (e-PCR)
- UniSTS:150494

RH65484 (e-PCR)
- UniSTS:54240

RH69580 (e-PCR)
- UniSTS:83688

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrial matrix	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: forkhead box protein O3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041757.1 Reference Mmul_10 Primary Assembly

Range

12240576..12366665

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001093593.4 → XP_001093593.1 forkhead box protein O3

See identical proteins and their annotated locations for XP_001093593.1

UniProtKB/TrEMBL

F6UMX8, I2CWQ1

Related

ENSMMUP00000071442.1, ENSMMUT00000096939.1

Conserved Domains (3) summary

pfam16675
Location:432 → 506

FOXO_KIX_bdg; KIX-binding domain of forkhead box O, CR2

pfam16676
Location:605 → 643

FOXO-TAD; Transactivation domain of FOXO protein family

cd20061
Location:156 → 238

FH_FOXO3; Forkhead (FH) domain found in Forkhead box protein O3 (FOXO3)