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    Smyd3 SET and MYND domain containing 3 [ Mus musculus (house mouse) ]

    Gene ID: 69726, updated on 5-May-2013
    Official Symbol
    Smyd3provided by MGI
    Official Full Name
    SET and MYND domain containing 3provided by MGI
    Primary source
    MGI:1916976
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zmynd1; 2410008A19Rik
    Location :
    1 H3; 1 83.48 cM
    Sequence :
    Chromosome: 1; NC_000067.6 (178955031..179518003, complement)
    See Smyd3 in Epigenomics, MapViewer

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene EF-hand calcium binding domain 2 Neighboring gene kinesin family member 26B Neighboring gene ribosomal protein L29 pseudogene Neighboring gene transcription factor B2, mitochondrial

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750.
    2. Cardiac deletion of Smyd2 is dispensable for mouse heart development. Diehl F, et al. PLoS One, 2010 Mar 17. PMID 20305823.
    3. Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex. Brown MA, et al. Mol Cancer, 2006 Jun 28. PMID 16805913.
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073.
    5. The transcriptional landscape of the mammalian genome. Carninci P, et al. Science, 2005 Sep 2. PMID 16141072.

    See all (18) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.
      Title: SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.
    Submit: New GeneRIF Correction
    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:213640 BioGRID:202996 Polr2a    BioGRID  PubMed Affinity Capture-Western 

    Markers

    Genotypes

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    histone-lysine N-methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    chromatin modification IEA
    Inferred from Electronic Annotation
    more info
    		  
    histone lysine methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
    		  
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Preferred Names
    histone-lysine N-methyltransferase SMYD3
    Names
    histone-lysine N-methyltransferase SMYD3
    zinc finger, MYND domain containing 1
    SET and MYND domain-containing protein 3
    zinc finger MYND domain-containing protein 1
    NP_081464.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027188.3 → NP_081464.1  histone-lysine N-methyltransferase SMYD3

      Status: PROVISIONAL

      Source sequence(s)
      AC117756, AC120870, AC130279, AC138225
      Consensus CDS
      CCDS15560.1
      UniProtKB/Swiss-Prot
      Q9CWR2
      Conserved Domains (2) summary
      pfam00856
      Location:194 – 239
      Blast Score: 159
      SET; SET domain
      pfam01753
      Location:49 – 87
      Blast Score: 152
      zf-MYND; MYND finger

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 103

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p1 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p1 C57BL/6J

      Range
      178955031..179518003, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000023.1 Alternate Mm_Celera

      Range
      186017554..186588962, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    genomic AAHY01002209.1 (2464..26868) None
    genomic AAHY01002210.1 None
    genomic AAHY01002211.1 None
    genomic AAHY01002212.1 None
    genomic AAHY01002213.1 None
    genomic AAHY01002214.1 None
    genomic AAHY01002215.1 None
    genomic AAHY01002216.1 None
    genomic AAHY01002217.1 None
    genomic AAHY01002218.1 None
    genomic AAHY01002219.1 None
    genomic AAHY01002220.1 None
    genomic AAHY01002221.1 None
    genomic AAHY01002222.1 None
    genomic AAHY01002223.1 None
    genomic AAHY01002224.1 None
    genomic AAHY01002225.1 None
    genomic AAHY01002226.1 None
    genomic AAHY01002227.1 None
    genomic AAHY01002228.1 None
    genomic AAHY01002229.1 None
    genomic AAHY01002230.1 None
    genomic AAHY01002231.1 None
    genomic AAHY01002232.1 None
    genomic AAHY01002233.1 None
    genomic AAHY01002234.1 None
    genomic AAHY01002235.1 None
    genomic AAHY01002236.1 None
    genomic AAHY01002237.1 None
    genomic AAHY01002238.1 None
    genomic AAHY01002239.1 None
    genomic AAHY01002240.1 None
    genomic AAHY01002241.1 None
    genomic AAHY01002242.1 None
    genomic AAHY01002243.1 None
    genomic AAHY01002244.1 None
    genomic AAHY01002245.1 None
    genomic AAHY01002246.1 None
    genomic AAHY01002247.1 None
    genomic AAHY01002248.1 None
    genomic AAHY01002249.1 (12375..23072) None
    genomic AC117756.8 (77737..174783) None
    genomic AC120870.8 None
    genomic AC130279.5 (21790..130479) None
    genomic AC138225.11 (130706..239758) None
    genomic AC164397.6 None
    genomic CH466555.2 EDL13170.1 mixed
      EDL13171.1 mixed
    mRNA AK010447.1 BAB26947.1 C57BL/6J
    mRNA AK043988.1 None C57BL/6J
    mRNA AK044168.1 BAC31804.1 C57BL/6J
    mRNA AK046829.1 BAC32887.1 C57BL/6J
    mRNA AK087728.1 BAC39984.1 C57BL/6J
    mRNA AK163057.1 BAE37175.1 C57BL/6J
    mRNA AK167875.1 BAE39889.1 DBA/2
    mRNA BC019663.1 None FVB/N
    mRNA BC038482.1 None CZECHII
    mRNA BC052431.1 AAH52431.1 C57BL/6
    mRNA BC061485.1 AAH61485.1 FVB/N-3
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CWR2.1 GenPept UniProtKB/Swiss-Prot:Q9CWR2

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

      Table of contents

      Related information

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        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed (GeneRIF)
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        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
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        Gene Genotype Report
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        Link to related taxonomy entry
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