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Tnfsf13 tumor necrosis factor (ligand) superfamily, member 13 [ Mus musculus (house mouse) ]

Gene ID: 69583, updated on 28-May-2016
Official Symbol
Tnfsf13provided by MGI
Official Full Name
tumor necrosis factor (ligand) superfamily, member 13provided by MGI
Primary source
MGI:MGI:1916833
See related
Ensembl:ENSMUSG00000089669 Vega:OTTMUSG00000006001
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
April; Tall2; Trdl1; Tnlg7b; 2310026N09Rik
Orthologs
Location:
11; 11 B4
Exon count:
6
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 11 NC_000077.6 (69682577..69685554, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (69496079..69499056, complement)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 4A1 Neighboring gene SUMO/sentrin specific peptidase 3 Neighboring gene tumor necrosis factor (ligand) superfamily, member 13, opposite strand Neighboring gene tumor necrosis factor (ligand) superfamily, membrane-bound member 13 Neighboring gene tumor necrosis factor (ligand) superfamily, member 12 Neighboring gene polymerase (RNA) II (DNA directed) polypeptide A

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Readthrough Tnfsfm13

Readthrough gene: Tnfsfm13, Included gene: Tnfsf12

Homology

Clone Names

  • MGC106105

Gene Ontology Provided by MGI

Function Evidence Code Pubs
cytokine activity IEA
Inferred from Electronic Annotation
more info
 
tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
immune response IEA
Inferred from Electronic Annotation
more info
 
immune system process IEA
Inferred from Electronic Annotation
more info
 
immunoglobulin mediated immune response IMP
Inferred from Mutant Phenotype
more info
PubMed 
immunoglobulin production in mucosal tissue IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of germinal center formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of isotype switching to IgA isotypes IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of isotype switching to IgA isotypes ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of immune response IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
tumor necrosis factor ligand superfamily member 13
Names
a proliferation-inducing ligand
tumor necrosis factor ligand 7b

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159505.1NP_001152977.1  tumor necrosis factor ligand superfamily member 13 isoform 2

    See identical proteins and their annotated locations for NP_001152977.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1. The resulting isoform (2) lacks one internal aa, compared to isoform 1.
    Source sequence(s)
    AK009514, AK134028, AL603707
    Consensus CDS
    CCDS48827.1
    UniProtKB/Swiss-Prot
    Q9D777
    UniProtKB/TrEMBL
    Q5F2A4
    Related
    ENSMUSP00000018896, OTTMUSP00000006221, ENSMUST00000018896, OTTMUST00000013436
    Conserved Domains (1) summary
    cd00184
    Location:108238
    TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...
  2. NM_023517.2NP_076006.2  tumor necrosis factor ligand superfamily member 13 isoform 1

    See identical proteins and their annotated locations for NP_076006.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK009514, AK134028, BY463961
    UniProtKB/Swiss-Prot
    Q9D777
    UniProtKB/TrEMBL
    Q5F2A4
    Conserved Domains (1) summary
    cd00184
    Location:108239
    TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p3 C57BL/6J

    Range
    69682577..69685554 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)